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ANCC Practice Questions – Adult-Gerontology Primary Care NP Exam Review (USA, 2025) – In-Depth Q&A with Rationales

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This study document provides 70+ high-yield practice questions and answer rationales for the Adult-Gerontology Primary Care Nurse Practitioner (AGPCNP) ANCC exam. It covers core areas such as hematology, dermatology, neurology, geriatrics, gynecology, public health, ethics, health promotion, infectious diseases, and pharmacology. Each question includes clinical reasoning explanations, guideline-based answers, and exam-relevant case scenarios, ideal for refining critical thinking and test readiness.

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ANCC Practice Questions
Adult-Gerontology Primary Care Nurse
Practitioner Review
I. Hematology
Iron Deficiency Anemia: Early Stages

 In the early stages of iron deficiency anemia, blood studies typically reveal a normochromic
normocytic presentation.
o (a) macrocytic normochromic: Characterizes other types of anemia.
o (b) microcytic hypochromic: A later finding in iron deficiency anemia.
o (c) normochromic normocytic: Correct. Indicates normal-sized and normal-colored red
blood cells, which can be present in early deficiency before changes in size and color
occur.
o (d) pancytopenic hypocytic: Indicates a deficiency in all blood cell types.


II. Dermatology
Eczema Risk Factors in Adolescents

 A 14-year-old male with a family history of eczema and a personal history of allergic rhinitis is
at increased risk for developing eczema. The third significant risk factor in this patient's history
is:
o (a) asthma: Correct. Asthma is a key component of the atopic triad,

which includes eczema, allergic rhinitis, and asthma.
o (b) bee allergy: While an allergy, it's not a primary risk factor for
eczema development.
o (c) otitis media: A common childhood infection, but not directly
linked as a major risk factor for eczema.
o (d) psoriasis: A distinct inflammatory skin condition.




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,III. Neurology
Assessing Ankle Clonus

 To assess for ankle clonus in a patient with hyperactive reflexes of the lower extremities, the
adult-gerontology primary care nurse practitioner performs the following action:
o (a) firmly applying a low-pitched tuning fork to the lateral malleolus: This assesses
vibratory sensation.
o (b) flexing the leg at the knee, rotating it externally, and striking the Achilles tendon
with the percussion hammer: This elicits the Achilles reflex.
o (c) sharply dorsiflexing the foot and maintaining this position while supporting the
knee: Correct. This maneuver stretches the gastrocnemius muscle and can elicit clonus
(rhythmic involuntary dorsiflexion and plantarflexion of the foot).
o (d) stroking the lateral aspect of the sole from the heel to the ball of the foot with the
sharp end of the percussion hammer: This elicits the Babinski reflex.

IV. Geriatrics & Gynecology
Prioritizing Physical Examination Findings in Older Women

 During a yearly evaluation of a 70-year-old female patient, the physical examination finding that
warrants the highest priority for immediate treatment is:
o (a) Atrophy of vaginal rugae: A normal age-related change due to decreased estrogen.
o (b) Cystocele present: A common finding in older women, but not typically requiring
immediate treatment unless symptomatic or severe.
o (c) Palpable ovary: Correct. A palpable ovary in a postmenopausal woman is abnormal
and requires immediate investigation to rule out malignancy.
o (d) Pessary in place: Indicates management of pelvic organ prolapse and is not an acute
concern.

V. Health Promotion & Patient Education
Health Belief Model: Perceived Severity

 A 16-year-old male patient who just received his driver's license states he doesn't need to wear a
seat belt because nothing will happen to him in a car collision. According to the Health Belief
Model, this patient lacks the chief component of:


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, o (a) Enabling factors: Resources or skills needed to adopt a behavior.
o (b) Motivation: The general desire to take action.
o (c) Perceived role conflict: Stress arising from competing social roles.
o (d) Perceived severity: Correct. The individual's belief about the seriousness of a
condition and its potential consequences.

VI. Epidemiology & Public Health
Documenting Epidemiological Factors for Biological Exposure

 When treating patients for biological exposure, the adult-gerontology primary care nurse
practitioner documents the following epidemiological factors for each exposure:
o (a) Comorbidities and length of exposure: Important for individual patient management
but not primary epidemiological factors.
o (b) Location and event intensity: Relevant to the context of the exposure but not the
core epidemiological determinants of disease spread.
o (c) Mode of transmission and incubation: Correct. These are fundamental
epidemiological factors that describe how the infectious agent spreads and the time
between exposure and symptom onset.
o (d) Premorbid conditions and surveillance rates: Surveillance rates are population-
level data, and premorbid conditions relate to individual susceptibility.

VII. Research & Evidence-Based Practice
Disseminating Research Findings

 When disseminating research findings in a peer-reviewed journal, the adult-gerontology primary
care nurse practitioner:
o (a) concludes that the study proves the hypothesis: Research studies support or fail to
support hypotheses; they rarely "prove" them definitively.
o (b) excludes the discussion section, because the conclusion contains this information:
The discussion section is crucial for interpreting results, limitations, and implications.
o (c) recommends incorporating the results directly into clinical practice:
Recommendations for practice change require careful consideration of the study's strength
and context.
o (d) uses the methodology section to support the validity of the study: Correct. A well-
described and rigorous methodology enhances the credibility and validity of the research
findings.



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, VIII. Ethics & Legal Considerations
Patient Confidentiality

 A patient's adult child telephones to inquire about the patient's illness, stating the parent relies on
the child for explanations. The nurse practitioner:
o (a) asks the child to provide a copy of the patient's advance directive document:
While relevant for decision-making capacity, it doesn't override current confidentiality.
o (b) assures the child that the nurse practitioner can disclose requested information:
This would be a breach of patient confidentiality.
o (c) informs the child that he or she must come to the clinic to discuss the parent's
case: While an option, it doesn't address the core issue of confidentiality.
o (d) tells the child that the nurse practitioner can discuss the information only with
the patient: Correct. Maintaining patient confidentiality is paramount unless the patient
has provided explicit consent for disclosure.

Role in Medical Ethics Review Committee

 The adult-gerontology primary care nurse practitioner appointed to a hospital's multidisciplinary
medical ethics review committee's role is to:
o (a) evaluate standards, risks, benefits, and outcomes: Correct. This committee
assesses the ethical implications of clinical decisions and policies.
o (b) identify how to anticipate and resolve similar future situations: While a potential
outcome, the primary role is evaluation.
o (c) investigate the need for disciplinary action: This is typically the role of other
committees.
o (d) obtain agreement of all parties with a chosen solution: The committee provides
recommendations, not necessarily mandates agreement.

Improving Quality of Clinical Practice

 To improve the quality of clinical practice, the adult-gerontology primary care nurse
practitioner:
o (a) charges a fee for patients who arrive late to clinic appointments: This addresses
efficiency, not necessarily the quality of clinical care itself.
o (b) disseminates research study results to colleagues: Correct. Sharing evidence-based
findings promotes informed practice and quality improvement.
o (c) expresses opinions about alternative therapies with patients who consider such
treatments: While important for patient education, it doesn't directly improve overall
clinical practice.

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