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f TABLE OF CONTENT
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Chapter f 1: f Pharmacokinetics
Chapter f2: fDrug–Receptor fInteractions fand fPharmacodynamics
f Chapter f3: f The f Autonomic fNervous fSystem
Chapter f4: fCholinergic fAgonists
fChapter f5: fCholinergic fAntagonists
fChapter f6: fAdrenergic fAgonists
fChapter f7: fAdrenergic fAntagonists
Chapter f8: fDrugs ffor fNeurodegenerative fDiseases
fChapter f9: fAnxiolytic fand fHypnotic fDrugs
Chapter f10: fAntidepressants
fChapter f11: fAntipsychotic fDrugs
fChapter f12: fDrugs ffor fEpilepsy
fChapter f13: fAnesthetics
Chapter f 14: f Opioids
Chapter f15: fDrugs fof fAbuse
fChapter f16: fCNS fStimulants
fChapter f17: fAntihypertensives
fChapter f18: fDiuretics
Chapter f 19: f Heart f Failure
Chapter f20: fAntiarrhythmics
fChapter f21: fAntianginal fDrugs
Chapter f22: fAnticoagulants fand fAntiplatelet fAgents
f Chapter f23: fDrugs ffor fHyperlipidemia
Chapter f24: fPituitary fand fThyroid
fChapter f25: fDrugs ffor fDiabetes
Chapter f26: fEstrogens fand fAndrogens
fChapter f27: fAdrenal fHormones
Chapter f 28: f Drugs f for f Obesity
Chapter f29: fDrugs ffor fDisorders fof fthe fRespiratory fSystem
f Chapter f30: fAntihistamines
Chapter f31: fGastrointestinal fand fAntiemetic fDrugs
fChapter f32: fDrugs ffor fUrologic f Disorders
Chapter f 33: f Drugs f for f Anemia
Chapter f34: fDrugs ffor fDermatologic fDisorders
fChapter f35: fDrugs ffor fBone fDisorders
Chapter f36: fAnti-inflammatory, fAntipyretic, fand f Analgesic fAgents
f Chapter f37: f Principles fof f Antimicrobial f Therapy
Chapter f 38: f Cell f Wall f Inhibitors
Chapter f 39: f Protein f Synthesis f Inhibitors
Chapter f40: fQuinolones, fFolic fAcid f Antagonists, f and f Urinary f Tract fAntiseptics
fChapter f41: fAntimycobacterial fDrugs
Chapter f42: fAntifungal fDrugs
fChapter f43: fAntiprotozoal fDrugs
fChapter f44: fAnthelmintic fDrugs
fChapter f45: fAntiviral fDrugs
Chapter f 46: f Anticancer f Drugs
Chapter f47: fImmunosuppressants
fChapter f48: fClinical fToxicology
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, 3. The nurse is teaching a patient who will be discharged home with a prescription for an enteric-
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coated tablet. Which statement by the patient indicates understanding of the teaching?
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a. I may crush the tablet and put it in applesauce to improve absorption.
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b. I should consume acidic foods to enhance absorption of this medication.
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c. I should expect a delay in onset of the drugs effects after taking the tablet.
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d. I should take this medication with high-fat foods to improve its action.
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ANS: C
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Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
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disintegrate when they reach the small intestine. There is usually some delay in onset of actions
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after taking these medications. Enteric-coated tablets should not be crushed or chewed, which
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would alter the time and location of absorption. Acidic foods will not enhance the absorption of the
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medication. The patient should not to eat high-fat food before ingesting an enteric-coated tablet,
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because high-fat foods decrease the absorption rate.
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DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
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TOP: NURSING PROCESS: Nursing Intervention
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MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
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4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be
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f given by subcutaneous injection instead of by mouth. The nurse willexplain that this is because
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a. absorption is diminished by the first-pass effects in the liver. f f f f f f f f f
b. absorption is faster when insulin is given subcutaneously. f f f f f f f
c. digestive enzymes in the gastrointestinal tract prevent absorption.
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d. the oral formis less predictable with more adverse effects.
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ANS: C
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Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by
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digestive enzymes and must be given parenterally. Because insulin is destroyed by digestive
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enzymes, it would not make it to the liver for metabolism with a first-pass effect. Subcutaneous
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tissue has fewer blood vessels, so absorption is slower in such tissue. Insulin is given
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subcutaneously because it is desirable to have it absorb slowly.
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DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
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TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
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MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
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