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Terms in this set (357)
Is the result of an autoimmune mediated
Explain the
specific loss of beta cells in the pancreatic
pathophysiology
islet. One of the basic patho of type 2 DM
associate with Type
is the development of insulin resistant
1 and Type 2 DM
tissue cells.
Explain what occurs Panhypopituitarism is the term correctly
in associated with the lack of all anterior
panhypopituitarism. pituitary hormones.
The individual develops a low basal
List the clinical
metabolic rate, cold intolerance, lethargy,
manifestations of
tiredness, and slightly lower basal body
hypothyroidism.
temperature.
, DM: is not a single disease but a group of
clinical heterogeneous disorders that have
glucose intolerance in common.
Differentiate DI: is an insufficiency of ADH, leading to
diabetes insipidus, polyuria and polydipsia.
diabetes mellitus
and SIADH. SIADH: is characterized by high levels of
ADH in the absence of normal
physiologic stimuli for its release.
The symptom common to all these
conditions is thirst.
What causes the Microvascular complications are a result
microvascular of capillary basement membranes
complications of thickening and endothelial cell
DM. hyperplasia.
Inability of the kidney to increase
permeability of water. This causes
What is the cause of
excretions of large volumes of dilute
diabetes insipidus.
urine, leading to increase in plasma
osmolality.
Describe the Addison disease is a result of
pathophysiological hyposecretion of adrenal cortex
changes associated hormones.
with Addison's
Disease.
, The most common cause of
Describe the
hyperparathyroidism is damage caused
pathophysiological
during thyroid surgery. In hypothyroidism
changes associated
a lack of circulating PTH causes a
with
depressed serum calcium level resulting in
hypoparathyroidism
the symptomatology mentioned in the
.
stem.
In a state of relative insulin deficiency
there is an increase in insulin counter
regulating hormones including
catecholamine's, cortisol, glucagon, and
GH. Catecholamine's, cortisol, glucagon
and GH antagonize insulin by increasing
What are the causes glucose production. In addition, these
and hormones decrease use of glucose.
pathophysiological Profound insulin deficiency results in
changes associate decrease glucose uptake, increase fat
with ketoacidosis? mobilization with release if fatty acids, and
accelerated gluconeogenesis and
ketogenesis. Ordinarily, ketones are used
by tissues as an energy source to
regenerate bicarbonate. Hyperkalemia is a
result of a compensatory mechanism
directed at eliminating metabolic acidosis.
Acromegaly is a term for adults who have
What is been exposed to continuously high levels
acromegaly? of GH, whereas the term gigantism is
reserved for children and adolescents.
, One of the cause's hypothyroidism is a
deficiency of endemic iodine.
Hypothyroidism are the lower levels of
thyroid hormone, without the negative
feedback of TH in the pituitary, there is an
increase secretion of TSH that may lead to
Differentiate goiter. As a result in decreased energy
hypothyroidism and metabolism resulting in constipation,
Graves' disease regulatory mechanisms are overridden by
abnormal immunologic mechanisms that
result in the stimulation of excessive TH.
The systemic symptoms of thyrotoxic
crisis include hyperthermia and
tachycardia; the remaining options are not
associated with this disorder.
A number of serious complications are
Describe the associated with any type of DM and
pathophysiology include microvascular (retinopathy,
related to chronic nephropathy, and neuropathy) and
DM macrovascular (CAD, CVA, PVD) disease
and infection.
A person with type 1 DM experiences
hunger, lightheadedness, tachycardia,
What happens pallor, HA and confusion. The most likely
during cause of these symptoms is
hypoglycemia? hypoglycemia, which is often caused by a
lack of systemic glucose resulting from
muscular activity.