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MCAT metabolism Questions with Detailed Verified
Answers (100% Correct Answers) /Already Graded
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Glycolysis
Ans: Breakdown of 6-carbon glucose molecule into two 3-carbon molecules
of pyruvate
Occurs in cytosol
Can occur with or without oxygen
10 steps
First half of glycolysis
Ans: Two phosphate groups from two different ATP molecules are added to
glucose (energy input phase)
AKA 6 carbon phase
Phosphate groups are bulky and charged: trap glucose inside the cell
They also prime the glucose, allowing the 6-carbon glucose to be split
Second half of glycolysis
Ans: Energy output phase
AKA 3 carbon phase
Two ATP produced per 3-C molecule (4 total)
One NADH produced from NAD per molecule (2 total)
Net yield from glycolysis
Ans: 2 ATP and 2 NADPH
Sunday, 02 March 2025
, Substrate-level phosphorylation
Ans: Production of ATP by the transfer of a phosphate molecule from a
molecule to an ADP
Fructose and galactose in glycolysis
Ans: Fructose and galactose are also able to feed into glycolysis
Usually converted to glucose by liver first
Fermentation
Ans: Metabolism in the absence of oxygen
Glucose undergoing anaerobic respiration
Reduction of pyruvate to ethanol (yeast and some microorganisms) or lactic
acid (human muscles and other microorganisms) in order to restore NADH
back to NAD
Ethanol/lactic acid and CO2 expelled as waste products
Yield: 2 ATP per glucose molecule
Pentose phosphate pathway
Ans: Diverges and merges back with glycolysis
Purpose: to create NADPH and some 5 carbon sugars
First half generates NADPH (various synthetic functions)
Second half (non-oxidative branch): Creates 5 C sugars
Active at all times
Occurs to some extent in all tissues, most common in tissues involved with
lipid synthesis (liver and adipocytes)
Regulated by NADPH (inhibits the first step)
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