Histology ASCP Exam ACTUAL EXAM
QUESTIONS WITH COMPLETE SOLUTION GUIDE)
(MULTIPLE CHOICES) (A+ GRADED 100%
VERIFIED) LATEST VERSION 2025
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An example of an additive Picric Acid
is one that contains:
A. Picric acid
B. Acetic acid
C. Ethyl alcohol
D. Acetone
When compared with Superior nuclear detail
tissue fixed in formalin,
tissue fixed in zinc-
formalin will show:
A. Better ultrastructural
preservation
B. Decreased
immunoreactivity
C. Increased enzyme
activity
D. Superior nuclear detail
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,5/7/25, 1:53 PM Histology ASCP Exam ACTUAL EXAM QUESTIONS WITH COMPLETE SOLUTION GUIDE) (MULTIPLE CHOICES) (A+ GRADED …
Microscopic examination Incomplete fixation
of an H&E stained section
fixed in formalin shows
marked nuclear bubbling.
One most often sees this
artifact if the specimen is
processed following:
A. Incomplete fixation
B. Prolonged fixation
C. Microwave fixation
D. Frozen sectioning
Microscopic evaluation of Delayed fixation
H&E stained sections from
a surgically removed small
bowel specimen shows an
absence of much of the
epithelium in otherwise
normal tissue. This most
likely resulted from:
A. Mechanical trauma
B. Delayed fixation
C. Ulceration
D. Poor choice of fixative
A specimen of kidney Michel solution
must be shipped to
another city for
immunofluorescence
studies. The specimen
should be placed in:
A. Saline
B. Michel solution
C. Buffered formalin
D. Orth solution
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A certain project requires Hollande solution
a fixative that contains
acetic acid yet stabilizes
erythrocyte membranes.
One fixative that could be
used is:
A. Zenker solution
B. Bouin solution
C. Gendre solution
D. Hollande solution
When the microwave oven Control of the temperature
is used for fixation, the
most critical factor is the:
A. Preparation of the
formalin solution
B. Use of glass containers
C. Control of the
temperature
D. Osmolality of the
fixative solution
To adequately remove the Hollande solution
calcium in a specimen
containing areas of
microcalcification, the
tissue could be fixed in:
A. Hollande solution
B. NBF
C. B-5 solution
D. Zamboni solution
What fixative contains Hollande
copper acetate?
A. Hollande
B. Bouin
C. Gendre
D. Zamboni
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A specimen is submitted Acidified with acetic acid
with the statement that it
was fixed in formalin.
Microscopic sections
show marked lysis of
erythrocytes. This
indicates that the fixative
most likely was:
A. Prepared with too
much formalin
B. Buffered above
neutrality
C. Acidified with acetic
acid
D. Not formalin
Fixatives are classified as Addition, or binding of the fixative to tissue proteins
additive because of the:
A. Addition of several
chemicals to the solution
B. Addition, or binding of
the fixative to tissue
proteins
C. Additional reactions
occurring with longer
fixation
D. Additional reactive
tissue sites available for
dye binding
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