Cancer Registry Operations Exam
2025 Questions and Answers
Casefinding - ANSWER✔✔-Systematic method of identifying all eligible cases that are
to be included in the cancer registry database
Case - ANSWER✔✔-The occurrence of a separate, independent diagnosis of cancer
Pathologically diagnosed - ANSWER✔✔-Means it was determined to be cancer through
a pathology specimen review (histology or cytology)
Clinically diagnosed - ANSWER✔✔-Means it was determined to be cancer by a
physician based on clinical findings, which can include physical findings, symptoms,
radiology, laboratory findings, or a combination.
Once a case becomes eligible for inclusion into the database, the COC requires the case
be: - ANSWER✔✔-Accessioned
Abstracted
Followed
,Histology - ANSWER✔✔-Type of cancer; includes carcinomas, melanoma, sarcoma,
lymphoma, and leukemia
Behavior code of 2 means: - ANSWER✔✔-in situ
Behavior code of 3 means: - ANSWER✔✔-Malignant
Behavior code of 0 means: - ANSWER✔✔-Benign
Behavior code of 1 means: - ANSWER✔✔-Borderline
Malignancies for all sites of the body with which behavior codes are required to be
included in registry database? - ANSWER✔✔-2 and 3
What are the 3 exceptions for reportability rules? - ANSWER✔✔-1. Juvenile
astrocytoma w/ behavior code of 1 MUST be included due to its devastating effect
2. Malignant primary skin cancers (C44.) with histology codes of 8000- 8110 are NOT
required (regardless of behavior code)
3. Carcinoma in situ of cervix; intraepithelial neoplasia grade III of the: cervix, prostate,
vulva, vagina, and anus are NOT required
Reference date - ANSWER✔✔-- Effective date in which cancer registration began for the
facility
, - All reportable cases diagnosed on or after this date must be included
- Usually January 1, (year)
Non- analytic cases - ANSWER✔✔-- Not required to be collected, abstracted, or
followed
- Do not meet CoC criteria for analytic case
- Cases in which reporting facility did not participate in either initially diagnosing
cancer, or delivering any of the first course of treatment
What are the three most common casefinding sources? - ANSWER✔✔-1. HIM disease
index
2. Pathology reports
3. Medical and radiation oncology reports
2025 Questions and Answers
Casefinding - ANSWER✔✔-Systematic method of identifying all eligible cases that are
to be included in the cancer registry database
Case - ANSWER✔✔-The occurrence of a separate, independent diagnosis of cancer
Pathologically diagnosed - ANSWER✔✔-Means it was determined to be cancer through
a pathology specimen review (histology or cytology)
Clinically diagnosed - ANSWER✔✔-Means it was determined to be cancer by a
physician based on clinical findings, which can include physical findings, symptoms,
radiology, laboratory findings, or a combination.
Once a case becomes eligible for inclusion into the database, the COC requires the case
be: - ANSWER✔✔-Accessioned
Abstracted
Followed
,Histology - ANSWER✔✔-Type of cancer; includes carcinomas, melanoma, sarcoma,
lymphoma, and leukemia
Behavior code of 2 means: - ANSWER✔✔-in situ
Behavior code of 3 means: - ANSWER✔✔-Malignant
Behavior code of 0 means: - ANSWER✔✔-Benign
Behavior code of 1 means: - ANSWER✔✔-Borderline
Malignancies for all sites of the body with which behavior codes are required to be
included in registry database? - ANSWER✔✔-2 and 3
What are the 3 exceptions for reportability rules? - ANSWER✔✔-1. Juvenile
astrocytoma w/ behavior code of 1 MUST be included due to its devastating effect
2. Malignant primary skin cancers (C44.) with histology codes of 8000- 8110 are NOT
required (regardless of behavior code)
3. Carcinoma in situ of cervix; intraepithelial neoplasia grade III of the: cervix, prostate,
vulva, vagina, and anus are NOT required
Reference date - ANSWER✔✔-- Effective date in which cancer registration began for the
facility
, - All reportable cases diagnosed on or after this date must be included
- Usually January 1, (year)
Non- analytic cases - ANSWER✔✔-- Not required to be collected, abstracted, or
followed
- Do not meet CoC criteria for analytic case
- Cases in which reporting facility did not participate in either initially diagnosing
cancer, or delivering any of the first course of treatment
What are the three most common casefinding sources? - ANSWER✔✔-1. HIM disease
index
2. Pathology reports
3. Medical and radiation oncology reports
