MH701 Frontier Prep Guide 2025/26 | Latest
Verified Quizzes and Answers | A+ Guarantee
What is pharmacodynamics? - What the drug does to the body
What is pharmacokinetics - What the body does to the drug (absorption, distribution,
metabolism, excretion)
Psychotropic medications - medications used to treat psychiatric disorders
What is pharmacogenetics - Explains how genetic variation leads to altered drug
responses in different individuals and ethnic groups
What is drug toxicity? - The degree to which a drug can be poisonous or harmful. it
occurs when too much of the drug is accumulated in the bloodstream. (CYP450 system
determines this)
What is steady state? - Condition in which the rate of absorption equals the rate of
elimination. It is acheived in 4-5 half-lives.
What is drug half-life? - The time required for the amount of drug in the body to
decrease by 50%
Classes of psychotropic drugs - Antidepressants
Antipsychotics
Mood stabilizers
Anxiolytics
Hypnotics
Cognitive enhancers, and Stimulants
Agonist - A chemical that mimics the action of a neurotransmitter. A drug or medication
that binds to a specific receptor producing an effect identical to that usually produced by the
neurotransmitter affecting that receptor.
Antagonist - A compound that binds to a receptor that blocks or reduces the action of
another substance (agonist) at the receptor site involved.
Antagonists that compete with an agonist for a receptor are competitive antagonists. Those that
antagonize by other means are noncompetitive antagonists
,Partial Agonist - Medication that produces a weaker, or less efficacious, response than an
agonist.
A compound that (even when fully occupying a receptor) possesses affinity for a receptor, but
elicits a partial pharmacological response at the receptor involved.
Inverse Agonist - Chemical substance that produces effects opposite those of a particular
neurotransmitter
What is the significance of understanding about CYP 450 when prescribing various medications
that may affect this? - Inducers-speed up other drugs' metabolism
Which equals leaving the body quicker
Which equal little to no effect intended effect.
Inhibitors- block the enzyme so decreases the body's ability to use drug
Which leaves too much circulating drug
What medications will most be affected by CYP 450? - Inducers
Mnemonic- CRAPGPS
Cabamazepine
Rifampin
Alcholol
Phenytion
Griseofulvin
Phenobarbital
Sulfonylureas
Inhibitors
Mnemonic- SICKFACES.COM@GQ
Sodium Valproate
Isoniazid
, Cimetidine
Ketoconazole
Fluconazole
Amiodarone/alcohol
Chloramphenicol
Erythromycin
Sulfonamides
Cipro
Omeprazole
Along with Grapefruit juice and Quinidine
What are the 4 tracts of the basal ganglia that can affect psychiatric or neurological disorders? -
Striatum (composed of the putamen and caudate nucleus)-(collectively, corpus striatum-
caudate and putamen components of motor and
association) is involved in the modulation of motor acts, and plays a role in OCD, Tourette's,
Parkinson's,
Huntington's, associative or cognitive processes. When the gateway is functioning normally, it
allows motor
system to perform only acts that are goal directed. When gateway fails - OCD.
Globus Pallidus-receives input from corpus striatum, damaged in Wilson's and carbon monoxide
poisoning and causes dystonic and flapping movements of extremities
Substantia Nigra-degenerates in Parkinson's, characterized by rigidity and tremor and is
associated with
depression in more than 30% of cases
Subthalamic nucleus-ballistic movements, sudden limb jerks like projectile movement
Verified Quizzes and Answers | A+ Guarantee
What is pharmacodynamics? - What the drug does to the body
What is pharmacokinetics - What the body does to the drug (absorption, distribution,
metabolism, excretion)
Psychotropic medications - medications used to treat psychiatric disorders
What is pharmacogenetics - Explains how genetic variation leads to altered drug
responses in different individuals and ethnic groups
What is drug toxicity? - The degree to which a drug can be poisonous or harmful. it
occurs when too much of the drug is accumulated in the bloodstream. (CYP450 system
determines this)
What is steady state? - Condition in which the rate of absorption equals the rate of
elimination. It is acheived in 4-5 half-lives.
What is drug half-life? - The time required for the amount of drug in the body to
decrease by 50%
Classes of psychotropic drugs - Antidepressants
Antipsychotics
Mood stabilizers
Anxiolytics
Hypnotics
Cognitive enhancers, and Stimulants
Agonist - A chemical that mimics the action of a neurotransmitter. A drug or medication
that binds to a specific receptor producing an effect identical to that usually produced by the
neurotransmitter affecting that receptor.
Antagonist - A compound that binds to a receptor that blocks or reduces the action of
another substance (agonist) at the receptor site involved.
Antagonists that compete with an agonist for a receptor are competitive antagonists. Those that
antagonize by other means are noncompetitive antagonists
,Partial Agonist - Medication that produces a weaker, or less efficacious, response than an
agonist.
A compound that (even when fully occupying a receptor) possesses affinity for a receptor, but
elicits a partial pharmacological response at the receptor involved.
Inverse Agonist - Chemical substance that produces effects opposite those of a particular
neurotransmitter
What is the significance of understanding about CYP 450 when prescribing various medications
that may affect this? - Inducers-speed up other drugs' metabolism
Which equals leaving the body quicker
Which equal little to no effect intended effect.
Inhibitors- block the enzyme so decreases the body's ability to use drug
Which leaves too much circulating drug
What medications will most be affected by CYP 450? - Inducers
Mnemonic- CRAPGPS
Cabamazepine
Rifampin
Alcholol
Phenytion
Griseofulvin
Phenobarbital
Sulfonylureas
Inhibitors
Mnemonic- SICKFACES.COM@GQ
Sodium Valproate
Isoniazid
, Cimetidine
Ketoconazole
Fluconazole
Amiodarone/alcohol
Chloramphenicol
Erythromycin
Sulfonamides
Cipro
Omeprazole
Along with Grapefruit juice and Quinidine
What are the 4 tracts of the basal ganglia that can affect psychiatric or neurological disorders? -
Striatum (composed of the putamen and caudate nucleus)-(collectively, corpus striatum-
caudate and putamen components of motor and
association) is involved in the modulation of motor acts, and plays a role in OCD, Tourette's,
Parkinson's,
Huntington's, associative or cognitive processes. When the gateway is functioning normally, it
allows motor
system to perform only acts that are goal directed. When gateway fails - OCD.
Globus Pallidus-receives input from corpus striatum, damaged in Wilson's and carbon monoxide
poisoning and causes dystonic and flapping movements of extremities
Substantia Nigra-degenerates in Parkinson's, characterized by rigidity and tremor and is
associated with
depression in more than 30% of cases
Subthalamic nucleus-ballistic movements, sudden limb jerks like projectile movement
