NURS 5315 INFLAMMATION EXAM QUESTIONS WITH
CORRECT DETAILED ANSWERS GRADED A+
Mast cell degranulation leads to: (5) - ✅✅Histamine
cytokines
leukotrienes
prostaglandins
platelet activating factor
histamine does what? - ✅✅vasodilation/increased permeability
increased blood flow to site
local swelling/erythema
cytokines do what (in mast cell degranulation) - ✅✅TNF--leukocyte emigration,
inc permeability
IL 13--chemotaxis, B cell proliferation and antibody productuon
IL4--Bcel proliferation and antibody production
,Which interlukin is elevated early in inflammation? - ✅✅IL4
Which interlukin is elevated later in inflammation? - ✅✅IL 13
TNF released when in inflammation process? - ✅✅early and late
function of leukotrines in mast cell degranulation - ✅✅Increase vascular
permeability
chemotaxis of neutrophils, eosinophils and macrophages
also known as slow
leukotrines also known as ____________________________________________
and do what to the inflammatory response - ✅✅slow reaction substances of
anaphyllaxis
prolong inflammatory response
function of prostoglandins in mast cell degranulation - ✅✅vasodilation and
platelet aggregation at site of injury
,pain and fever
Which action is a purpose of the inflammatory process?
a. To provide specific responses toward antigens
b. To lyse cell membranes of microorganisms
c. To prevent infection of the injured tissue
d. To create immunity against subsequent tissue injury - ✅✅ANS: C
If the epithelial barrier is damaged, then a highly efficient local and systemic
response (inflammation) is mobilized to limit the extent of damage, to protect
against infection, and to initiate the repair of damaged tissue. The other options do
not accurately identify a purpose of the inflammatory process.
How do surfactant proteins A through D provide innate resistance?
a. Initiate the complement cascade.
b. Promote phagocytosis
c. Secrete mucous
d. Synthesize lysosomes - ✅✅ANS: B
, The lung produces and secretes a family of glycoproteins, collectins, which
includes surfactant proteins A through D and mannose-binding lectin. Collectin
binding facilitates macrophages to recognize the microorganism, enhancing
macrophage attachment, phagocytosis, and killing.
What causes the edema that occurs during the inflammatory process?
a. Vasodilation of blood vessels
b. Increased capillary permeability
c. Endothelial cell contraction
d. Emigration of neutrophils - ✅✅ANS B
cellular injury leads to: (5) - ✅✅1. coagulation cascade activation
2. Kinin system activation
3. Mast cell degranulation
4. Complement cascade activation
5. chemotactic factors released
Coagulation cascade activation leads to (4) - ✅✅fibrin mesh containing the
injury
CORRECT DETAILED ANSWERS GRADED A+
Mast cell degranulation leads to: (5) - ✅✅Histamine
cytokines
leukotrienes
prostaglandins
platelet activating factor
histamine does what? - ✅✅vasodilation/increased permeability
increased blood flow to site
local swelling/erythema
cytokines do what (in mast cell degranulation) - ✅✅TNF--leukocyte emigration,
inc permeability
IL 13--chemotaxis, B cell proliferation and antibody productuon
IL4--Bcel proliferation and antibody production
,Which interlukin is elevated early in inflammation? - ✅✅IL4
Which interlukin is elevated later in inflammation? - ✅✅IL 13
TNF released when in inflammation process? - ✅✅early and late
function of leukotrines in mast cell degranulation - ✅✅Increase vascular
permeability
chemotaxis of neutrophils, eosinophils and macrophages
also known as slow
leukotrines also known as ____________________________________________
and do what to the inflammatory response - ✅✅slow reaction substances of
anaphyllaxis
prolong inflammatory response
function of prostoglandins in mast cell degranulation - ✅✅vasodilation and
platelet aggregation at site of injury
,pain and fever
Which action is a purpose of the inflammatory process?
a. To provide specific responses toward antigens
b. To lyse cell membranes of microorganisms
c. To prevent infection of the injured tissue
d. To create immunity against subsequent tissue injury - ✅✅ANS: C
If the epithelial barrier is damaged, then a highly efficient local and systemic
response (inflammation) is mobilized to limit the extent of damage, to protect
against infection, and to initiate the repair of damaged tissue. The other options do
not accurately identify a purpose of the inflammatory process.
How do surfactant proteins A through D provide innate resistance?
a. Initiate the complement cascade.
b. Promote phagocytosis
c. Secrete mucous
d. Synthesize lysosomes - ✅✅ANS: B
, The lung produces and secretes a family of glycoproteins, collectins, which
includes surfactant proteins A through D and mannose-binding lectin. Collectin
binding facilitates macrophages to recognize the microorganism, enhancing
macrophage attachment, phagocytosis, and killing.
What causes the edema that occurs during the inflammatory process?
a. Vasodilation of blood vessels
b. Increased capillary permeability
c. Endothelial cell contraction
d. Emigration of neutrophils - ✅✅ANS B
cellular injury leads to: (5) - ✅✅1. coagulation cascade activation
2. Kinin system activation
3. Mast cell degranulation
4. Complement cascade activation
5. chemotactic factors released
Coagulation cascade activation leads to (4) - ✅✅fibrin mesh containing the
injury
