Chemo/Bio
____ is a form of most cancers where the tumor is made up of cancerous cells that seem like
immature muscle cells. - ANS-Rhabdomyosarcoma
A nurse can provide a biotherapy (ie. Rituxamab) with out taking APHON. - ANS-FALSE. ALL
biotherpies are required to take delivery of by way of nurses maintaining the chemo bio
competency.
Adjuvant remedy: - ANS-Chemotherapy is used in sufferers who have has surgical operation or
radiation remedy for malignancies with a excessive danger of residual disease or undetected
metastases.
After receiving chemotherapy, the nurse ought to deal with the patient's physical fluids with
unsafe drug precautions for a way long after final touch of remedy? - ANS-forty eight hours
Antimetabolities prevent this phase of the mobile cycle: - ANS-Synthesis
Apoptosis - ANS-programmed everyday cellular dying
Biotherapy can be classified by means of mechanism of action into three major divisions: -
ANS-1. Agents that augment, modulate, or repair the host's immune responses.
2. Agents which have direct anti tumor hobby.
Three. Agents that have other organic consequences (e.G.. Differentiation retailers, sellers that
have an effect on the tumor's ability to metastasize, or sellers affecting cellular transformation).
Can you administer chemotherapy/biotherapy if the VAD has no blood go back? - ANS-NO.
Cell cycle non precise sellers have cytotoxic consequences at some point of which levels of the
cell cycle? - ANS-All
Cell cycle particular retailers are handiest if administered in: - ANS-divided doses or continous
infusion
Cell cycle unique agents have the maximum cytotoxic impact all through the energetic ____
and____ phases of the mobile cycle. - ANS-S and M
Cell non particular marketers are best if adminstered by way of ___ dosing. - ANS-Bolus
Cell non particular agents consist of these forms of chemotherapy: - ANS--Alkylating sellers,
antitumor antibodies, hormonal marketers, topoisomerase I inhibitors
, Chemotherapy agents utilized in mixture are chosen based upon the subsequent: - ANS-1.
Individual pastime towards a selected sickness.
2. Ability to exert outcomes at distinct stages of the cellular cycle.
Three. Different Side effect profiles to prevent overlapping treatment toxicities.
4. Synergy (superior activity while used collectively)
Chemotherapy drug elegance that arrests cells inside the metaphase and save you spindle
formation with the aid of binding to the microtubules. Example: Vincristine - ANS-Plant Alkaloids
Chemotherapy drug class that binds to DNA and intervene with in addition replication of DNA
and transpiration of RNA. Active in all phases. Example: Doxorubicin - ANS-Antitumor
antibodies
Chemotherapy drug elegance that has important metabolic elements needed for mobile
increase and are altered so that synthesis of RNA and DNA are inhibited. Example:
Methotrexate - ANS-Antimetabolites
Chemotherapy drug elegance that Inhibits replication inflicting cellular loss of life, maximum
active within the resting phase- G) Example: Cytoxan - ANS-Alkylating dealers
Combination chemotherapy is superior to unmarried dose marketers because it produces: -
ANS-a higher tumor reaction charge; an improved length of remission, and a discount within the
development of new, resistant cell groups.
Combination chemotherapy: - ANS-The use of or greater drugs given simultaneously or in
series if you want to gain the great healing reaction inside various toxicity tolerated by using the
host. Drugs are given at normal periods (cycles) to optimize the dosage and schedule.
Common aspect effect of Hydroxyurea: - ANS-Myelosuppression with speedy drop in WBC
Cytoxan is a cell cycle particular or cell cycle non unique agent? - ANS-Cell cycle non particular
agent. It has cytotoxic consequences in the course of ALL levels of the mobile cycle.
Describe how to perform a bedside independently double take a look at before administering an
IV chemotherapy. - ANS-One chemo/ bio comptent nurses reads the sufferers bracelet; MRN
variety, call date of beginning and the other chemo/ bio equipped nurse suits it in opposition to
the drug label. The bedside chemo/ bio nurse programs the pump and the 2d chemo/ bio nurse
independently exams the pump.
Drugs which have the suffix "-momab, -ximab, -zumab, -umab": - ANS-Monoclonal Antibodies
Drugs that Inhibi tumor proliferation by blockading obviously occurring substances that stimulate
tumor boom. Examples: prednisone and dexamethasone - ANS-Steroids
____ is a form of most cancers where the tumor is made up of cancerous cells that seem like
immature muscle cells. - ANS-Rhabdomyosarcoma
A nurse can provide a biotherapy (ie. Rituxamab) with out taking APHON. - ANS-FALSE. ALL
biotherpies are required to take delivery of by way of nurses maintaining the chemo bio
competency.
Adjuvant remedy: - ANS-Chemotherapy is used in sufferers who have has surgical operation or
radiation remedy for malignancies with a excessive danger of residual disease or undetected
metastases.
After receiving chemotherapy, the nurse ought to deal with the patient's physical fluids with
unsafe drug precautions for a way long after final touch of remedy? - ANS-forty eight hours
Antimetabolities prevent this phase of the mobile cycle: - ANS-Synthesis
Apoptosis - ANS-programmed everyday cellular dying
Biotherapy can be classified by means of mechanism of action into three major divisions: -
ANS-1. Agents that augment, modulate, or repair the host's immune responses.
2. Agents which have direct anti tumor hobby.
Three. Agents that have other organic consequences (e.G.. Differentiation retailers, sellers that
have an effect on the tumor's ability to metastasize, or sellers affecting cellular transformation).
Can you administer chemotherapy/biotherapy if the VAD has no blood go back? - ANS-NO.
Cell cycle non precise sellers have cytotoxic consequences at some point of which levels of the
cell cycle? - ANS-All
Cell cycle particular retailers are handiest if administered in: - ANS-divided doses or continous
infusion
Cell cycle unique agents have the maximum cytotoxic impact all through the energetic ____
and____ phases of the mobile cycle. - ANS-S and M
Cell non particular marketers are best if adminstered by way of ___ dosing. - ANS-Bolus
Cell non particular agents consist of these forms of chemotherapy: - ANS--Alkylating sellers,
antitumor antibodies, hormonal marketers, topoisomerase I inhibitors
, Chemotherapy agents utilized in mixture are chosen based upon the subsequent: - ANS-1.
Individual pastime towards a selected sickness.
2. Ability to exert outcomes at distinct stages of the cellular cycle.
Three. Different Side effect profiles to prevent overlapping treatment toxicities.
4. Synergy (superior activity while used collectively)
Chemotherapy drug elegance that arrests cells inside the metaphase and save you spindle
formation with the aid of binding to the microtubules. Example: Vincristine - ANS-Plant Alkaloids
Chemotherapy drug class that binds to DNA and intervene with in addition replication of DNA
and transpiration of RNA. Active in all phases. Example: Doxorubicin - ANS-Antitumor
antibodies
Chemotherapy drug elegance that has important metabolic elements needed for mobile
increase and are altered so that synthesis of RNA and DNA are inhibited. Example:
Methotrexate - ANS-Antimetabolites
Chemotherapy drug elegance that Inhibits replication inflicting cellular loss of life, maximum
active within the resting phase- G) Example: Cytoxan - ANS-Alkylating dealers
Combination chemotherapy is superior to unmarried dose marketers because it produces: -
ANS-a higher tumor reaction charge; an improved length of remission, and a discount within the
development of new, resistant cell groups.
Combination chemotherapy: - ANS-The use of or greater drugs given simultaneously or in
series if you want to gain the great healing reaction inside various toxicity tolerated by using the
host. Drugs are given at normal periods (cycles) to optimize the dosage and schedule.
Common aspect effect of Hydroxyurea: - ANS-Myelosuppression with speedy drop in WBC
Cytoxan is a cell cycle particular or cell cycle non unique agent? - ANS-Cell cycle non particular
agent. It has cytotoxic consequences in the course of ALL levels of the mobile cycle.
Describe how to perform a bedside independently double take a look at before administering an
IV chemotherapy. - ANS-One chemo/ bio comptent nurses reads the sufferers bracelet; MRN
variety, call date of beginning and the other chemo/ bio equipped nurse suits it in opposition to
the drug label. The bedside chemo/ bio nurse programs the pump and the 2d chemo/ bio nurse
independently exams the pump.
Drugs which have the suffix "-momab, -ximab, -zumab, -umab": - ANS-Monoclonal Antibodies
Drugs that Inhibi tumor proliferation by blockading obviously occurring substances that stimulate
tumor boom. Examples: prednisone and dexamethasone - ANS-Steroids
