NR565 EXAM PREP/ NR 565 FINAL EXAM (CHAMBERLAIN)
NEWEST 2025 TEST BANK| ADVANCED PHARMACOLOGY
FUNDAMENTALS EXAM| COMPLETE 450 ACTUAL EXAM
QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) ALREADY GRADED A+||BRAND NEW
Which drug class has no significant drug interactions: cold and cough -
ANSWER - expectorants
H2 receptor antagonists examples - ANSWER - Cimetidine (Tagamet),
famotidine (Pepcid), nizatidine (Axid), ranitidine (Zantac).
Which is most likely to interact due to CYP450 enzyme system? -
ANSWER - Cimetidine (Tagamet)
Proton Pump Inhibitors - ANSWER - First-line therapy. Omeprazole
(Prilosec), esomeprazole (nexium), pantoprazole (protonix)
Associated vitamin and/or mineral deficiencies with PPI - ANSWER -
Decreased absorption of calcium, magnesium, and vitamin B12.
Short term use increases risk of what with PPI - ANSWER -
Community-acquired pneumonia (CAP, first few days), rebound GERD-
use lowest does for shortest period of time and tapper. Can persist for
several months after PPI dc, diarrhea (dose related) Cdiff
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How to treat moderate to severe GERD - ANSWER - Long-term
maintenance therapy of PPI is recommended for severe. Moderate???
What medication for GERD to avoid in older adults and why? -
ANSWER - Renal (famotidine aka Pepcid), Ranitidine and cimetidine
due to risks for mental status changes, nizatidine (axid) heart and liver.
Treating GERD during pregnancy - ANSWER - Some PPIs
(esomeprazole) and H2 receptor antagonists (ranitidine) are safe for use
in pregnancy.
Which cytoprotective agents would be used: - ANSWER - Sucralfate -
NOT misoprostol
When to test for h. Pylori: - ANSWER - If on treatment and not getting
better. Consider testing before prescribing H2 receptor antagonists/PPIs.
How to treat h. Pylori - ANSWER - Continue PPIs for 8-12 weeks, low-
risk maybe no treatment, high-risk may require chronic acid suppression
therapy. GI referral if no relief.
Lifestyle modifications to support ulcer healing - ANSWER - Stop
smoking, change in eating pattern (smaller meals and avoiding caffeine),
avoid aspirin and NSAIDs, stop alcohol consumption, decrease stress
and anxiety.
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Which antidiarrheal contradicted in children during or after chickenpox -
ANSWER - Salicylate component of pepto
Patient teaching for ciprofloxacin for traveler's diarrhea: Neena is
planning missionary work in a region with poor drinking water. She is
given a prescription for ciprofloxacin to take with her. Which of the
following instructions are most important to discuss with Neena? -
ANSWER - · Use the drug if symptoms develop and are severe or do not
improve in a few days.
Which one associated with gray/black stools and black tongue -
ANSWER - Pepto - result from bismuth that make up pepto.
· Constipation
Lifestyle modifications to suggest prior to treatment - ANSWER -
Increasing fiber and fluid in the diet, mild exercise.
Risks of laxatives during pregnancy - ANSWER - Gastrointestinal
stimulation can induce labor.
Signs and symptoms of hypothyroidism - ANSWER - Face is pale,
puffy, and expressionless.
Skin is cold and dry.
hair is brittle, and hair loss occurs.
Heart rate and temperature are lowered. The patient lethargy, fatigue,
and intolerance to cold.
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Mentation may be impaired.
Signs and symptoms of hyperthyroidism - ANSWER - Heart Rate is
Rapid; Possible arrhythmia/angina
Nervousness, insomnia, rapid thought flow, and rapid speech
Skeletal muscles may weaken and atrophy
Metabolic rate is raised, resulting in increased heat production, increased
body temperature, intolerance to heat, and skin that is warm and moist
Weight loss occurs if caloric intake fails to match the increase in
metabolic rate
Severe hypothyroidism - ANSWER - Myxedema
Hypothyroid Treatment - ANSWER - Levothyroxine is the drug of
choice for most patients who require thyroid hormone replacement.
Levothyroxine (Synthroid) Therapeutic Goal - ANSWER - Resolution of
signs and symptoms of hypothyroidism and restoration of normal
laboratory values for serum thyroid-stimulating hormone (TSH) and free
thyroxine (T4).
Major forms of hyperthyroidism - ANSWER - Graves disease and toxic
nodular goiter (also known as Plummer disease).
Graves Disease - ANSWER - Most common cause of excessive thyroid
hormone secretion
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