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Exam (elaborations)

NSG 532 EXAM 1 COMPREHENSIVE QUESTIONS WITH COMPLETE ANSWERS

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NSG 532 EXAM 1 COMPREHENSIVE QUESTIONS WITH COMPLETE ANSWERS

Institution
Rush University
Course
NSG 532











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Uploaded on
April 21, 2025
Number of pages
265
Written in
2024/2025
Type
Exam (elaborations)
Contains
Questions & answers

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1 of 321

Term



Why is a unipotent stem cell still considered a stem cell?



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They are packed into protein transport vesicles and complete their modifications in
the golgi

, Have the property of self renewal - which distinguishes from non-stem cells.
Examples are egg and sperm unipotent stem cells.




Essential for the cell cycle phase transitions


Each phase of the cell cycle must be successfully completed before the next phase
can be entered


Each phase is carefully regulated




Ion channel proteins and cell membrane receptors become fully fused with the cell
membrane


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2 of 321

Definition



Abnormal alterations in the composition/diversity of the microbiome



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Define dysbiosis Describe what caspases are




Define genotype Define senescence


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, 3 of 321

Term



Describe the structure and function of glycerophospholipids



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Phospholipids w/a glycerol backbone

Phosphate attached to amino acid alcohol

Most common serine, choline, inositol


Regulate of activity of membrane bound enzymes, ion channels, and
apoptosis




Ligand binding triggers receptor dimerization

Tyrosine receptor in the cytoplasmic portion becomes phosphorylated -- becomes
activated

Intracellular signal proteins bind to activated RTK and become activated
themselves.




Spliceosome is responsible for the process of splicing to remove introns and join
exons

Iron binding proteins inhibit the binding of spliceosome to primary mRNA

Sends a signal for degradation of unfinished pre mRNA

, Protects genes from innapropriate signals that arise from their surrounding
environment


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4 of 321

Term



Describe the function of Small Interfering RNA (snRNA)



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Phagocytosis - particles are useless and external
Taken up into endosomes to form phagosomes

Autophagy - particles are useless internal organelles and taken up into the ER
membrane to form autophagosomes




A barrier to water and water soluble substances

Organized in a bilayer

Contain 2 fatty acids, 1 glycerol and 1 phosphate


Fatty acids provide a hydrophobic barrier

Glycerol and phosphate are hydrophillic

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