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Mitosis in neural epithelial progenitors occurs at the ventricular surface. A __________ allows
one cell to differentiate while the other cell maintains as a NEP. asymmetric division
Radial glia give rise to neurons and glia. Radial glia also direct cell migration because they
____________. anchor to the ventricular and pial surface to provide structural support
Neurons in the central nervous system are nourished by ________, and myelinated by
________. astrocytes, oligodendrocytes
The _____________ cells line the ventricles of the brain. Fill in the blank. Ependymal
BrdU is a compound that incorporates into dividing cells. Following injection of BrdU into an
embryonic rat, you analyze the cerebral cortex at birth and note a number of labeled neurons in
upper cortical layers, Layer 2/3. What embryonic stage did you likely administer the BrdU?
Near the end of the period of neurogenesis
A dominant modality to expand the stem cell pool is to allow stem cells to divide symmetrically.
True
, Which of the following is the primary reason for the stereotyped, segmental pattern of
peripheral nerve outgrowth as shown in the image of a whole-mount neurofilament stained
mouse embryo on the right? Neural crest are repelled from the caudal/posterior somite by
Eph/Ephrin signaling
Eph/Ephrin signaling is an example of _____________ signaling and is ______________ . Fill in
the blanks with the best answer. juxtacrine, bidirectional
In the peripheral nervous system, which of the following are neural crest derived? dorsal
root ganglia sensory neurons
You create an EphrinB2 knockout mouse. Where would you expect to see neural crest cells
migrate? In all regions of somites
Axonal growth cones are highly dynamic structures with finger like extensions known as ______
and wave like extensions called lamellipodia. _______ family members play important roles in
modulating cytoskeletal changes during growth cone turning. Fill in the blanks. Filopodia,
Rho GTPase
In the experiment shown below, a compound is administered near the growing neuron at 2
min., resulting in an effect by 10 min. Based on these data, you would conclude that this
compound ________________ the __________________. Fill in the blanks with the best
answer. attracts, axonal growth cone