AAB MT Hematology Exam 2025 With
100% Correct Answers
What is hemoglobin composed of?
A. 4 heme, 4 iron, 4 globins
B. 4 heme, 4 iron, 1 globin
C. 2 heme, 2 iron, 2 globins
D. 1 heme, 1 iron, 1 globin - correct answers ✔✔A. 4 heme, 4 iron, 4 globins
What disorder does a defect in heme synthesis lead to?
A. hemoglobinopathy
B. coagulopathy
C. thalassemia
D. porphyria - correct answers ✔✔D. porphyria
What is the function of the enzyme methemoglobin-cytochrome C reductase in red blood cell?
A. to keep iron in the ferric state
B. to keep iron in the ferrous state
C. to maintain an anaerobic pathway for glycolysis
D. to maintain an aerobic pathway for the Krebs cycle - correct answers ✔✔B. to keep iron in
the ferrous state
,Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than
oxygen?
A. carboxyhemoglobin
B. oxyhemoglobin
C. sulfhemoglobin
D. methemoglobin - correct answers ✔✔A. carboxyhemoglobin
What product is formed when ferrous iron of hemoglobin is oxidized to the ferric state?
A. sulfhemoglobin
B. methemoglobin
C. carboxyhemoglobin
D. cyanmethemoglobin - correct answers ✔✔B. methemoglobin
Which hemoglobin derivative causes irreversible changes in the red blood cells?
A. sulfhemoglobin
B. methemoglobin
C. carboxyhemoglobin
D. cyanmethemoglobin - correct answers ✔✔A. sulfhemoglobin
Which of the following hemoglobin is NOT normally present in a normal adult?
A. Hb-A1
B. Hb-A
,C. Hb-S
D. Hb-F - correct answers ✔✔C. Hb-S
Which embryonic hemoglobin is normally found in newborns?
A. Hb-F
B. Hb-Gower1
C. Hb-Gower2
D. Hb-Portland - correct answers ✔✔A. Hb-F
What is the most abundant hemoglobin in a newborn?
A. Hb-Gower
B. Hb-A1
C. Hb-A2
D. Hb-F - correct answers ✔✔D. Hb-F
What is the molecular structure of hemoglobin S?
A. valine replaces glutamic acid in the 6th position of the beta chain
B. lysine replaces glutamic acid in the 6th position of the beta chain
C. lysine replaces glutamine in the 26th position of the beta chain
D. valine replaces glutamine in the 26th position of the beta chain - correct answers ✔✔A.
valine replaces glutamic acid in the 6th position of the beta chain
Which of the following hemoglobin is insoluble under lowered oxygen tension?
, A. Hb-A
B. Hb-S
C. Hb-C
D. Hb-F - correct answers ✔✔B. Hb-S
What laboratory test is used to confirm the specific diagnosis of sickle cell anemia?
A. solubility test
B. sodium metabisulfite test
C. hemoglobin electrophoresis
D. presence of sickle cells in the peripheral smear - correct answers ✔✔C. hemoglobin
electrophoresis
In the solubility test for hemoglobin S, what is the reagent responsible for the reduction of the
hemoglobin molecule??
A. saponin
B. sodium dithionite
C. sodium hydroxide
D. ammonium sulfate - correct answers ✔✔B. sodium dithionite
In hemoglobin C, what replace glutamic acid?
A. lysine
B. valine
C. cystine
100% Correct Answers
What is hemoglobin composed of?
A. 4 heme, 4 iron, 4 globins
B. 4 heme, 4 iron, 1 globin
C. 2 heme, 2 iron, 2 globins
D. 1 heme, 1 iron, 1 globin - correct answers ✔✔A. 4 heme, 4 iron, 4 globins
What disorder does a defect in heme synthesis lead to?
A. hemoglobinopathy
B. coagulopathy
C. thalassemia
D. porphyria - correct answers ✔✔D. porphyria
What is the function of the enzyme methemoglobin-cytochrome C reductase in red blood cell?
A. to keep iron in the ferric state
B. to keep iron in the ferrous state
C. to maintain an anaerobic pathway for glycolysis
D. to maintain an aerobic pathway for the Krebs cycle - correct answers ✔✔B. to keep iron in
the ferrous state
,Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than
oxygen?
A. carboxyhemoglobin
B. oxyhemoglobin
C. sulfhemoglobin
D. methemoglobin - correct answers ✔✔A. carboxyhemoglobin
What product is formed when ferrous iron of hemoglobin is oxidized to the ferric state?
A. sulfhemoglobin
B. methemoglobin
C. carboxyhemoglobin
D. cyanmethemoglobin - correct answers ✔✔B. methemoglobin
Which hemoglobin derivative causes irreversible changes in the red blood cells?
A. sulfhemoglobin
B. methemoglobin
C. carboxyhemoglobin
D. cyanmethemoglobin - correct answers ✔✔A. sulfhemoglobin
Which of the following hemoglobin is NOT normally present in a normal adult?
A. Hb-A1
B. Hb-A
,C. Hb-S
D. Hb-F - correct answers ✔✔C. Hb-S
Which embryonic hemoglobin is normally found in newborns?
A. Hb-F
B. Hb-Gower1
C. Hb-Gower2
D. Hb-Portland - correct answers ✔✔A. Hb-F
What is the most abundant hemoglobin in a newborn?
A. Hb-Gower
B. Hb-A1
C. Hb-A2
D. Hb-F - correct answers ✔✔D. Hb-F
What is the molecular structure of hemoglobin S?
A. valine replaces glutamic acid in the 6th position of the beta chain
B. lysine replaces glutamic acid in the 6th position of the beta chain
C. lysine replaces glutamine in the 26th position of the beta chain
D. valine replaces glutamine in the 26th position of the beta chain - correct answers ✔✔A.
valine replaces glutamic acid in the 6th position of the beta chain
Which of the following hemoglobin is insoluble under lowered oxygen tension?
, A. Hb-A
B. Hb-S
C. Hb-C
D. Hb-F - correct answers ✔✔B. Hb-S
What laboratory test is used to confirm the specific diagnosis of sickle cell anemia?
A. solubility test
B. sodium metabisulfite test
C. hemoglobin electrophoresis
D. presence of sickle cells in the peripheral smear - correct answers ✔✔C. hemoglobin
electrophoresis
In the solubility test for hemoglobin S, what is the reagent responsible for the reduction of the
hemoglobin molecule??
A. saponin
B. sodium dithionite
C. sodium hydroxide
D. ammonium sulfate - correct answers ✔✔B. sodium dithionite
In hemoglobin C, what replace glutamic acid?
A. lysine
B. valine
C. cystine
