Correct Answers
Which one of the following definitions best describes an enzyme? - correct answers
✔✔biological catalyst
What is the true of an isoenzyme? - correct answers ✔✔The electrophoretic property is
different for each isoenzyme.
Why is a metal ion sometimes necessary in an enzymatic reaction? - correct answers ✔✔acts as
an activator of the enzyme
The Michaelis-Menten constant in the rate of conversion of substrate to products is determined
by what factor? - correct answers ✔✔substrate concentration and the rate of dissociation of the
complex
In a zero-order reaction, there will be no further increase in velocity due to which one of the
following? - correct answers ✔✔all enzyme is bound to substrate
What is the reporting unit of measure for enzymes? - correct answers ✔✔IU/L
Which enzyme catalyxes this reaction? lactate + NAD>pyruvate + NADH - correct answers
✔✔lactate dehydrogenase
Which of the following is true of the isoenzyme LD1? - correct answers ✔✔It is present in the
highest concentration in the heart tissue
, Which enzyme is most greatly affected by hemolysis? - correct answers ✔✔lactate
dehydrogenase
An LD isoenzyme electrophoretic pattern that shows an increase in LD1, LD2 and LD3 is seen in
which disease state? - correct answers ✔✔pernicious anemia
Creatine kinase is clinically significant in diseases of which organ? - correct answers ✔✔muscle
Creatine kinase in frequently elevated in acute myocardial infarction and which other disorder?
- correct answers ✔✔Duchenne's muscular dystrophy
Which serum enzyme begins to rise 2 to 4 hours, has a peak activity occurring 12 to 36, and
returns to normal 2 to 4 days after an acute myocardial infarction? - correct answers
✔✔creatine kinase
Aspartate transaminase is elevated in all of the following except
myocardial infarction
muscular dystrophy
acute pancreatitis
liver disease - correct answers ✔✔acute pancreatitis
Which enzyme is liver specific - correct answers ✔✔ALT- alanine transaminase
Which enzyme is the most sensitive indicator of obstructive jaudice? - correct answers ✔✔Alk
Phos- alkaline phosphatase
A high alkaline phos level in the presence of other negative liver function tests is indicative of
which disorder? - correct answers ✔✔bone disorder