MKSAP Boards Basics - Endocrinology and
Metabolism UPDATED ACTUAL Exam
Questions and CORRECT Answers
What DM drugs help with weight loss? - CORRECT ANSWER - GLP-1, pramlintide, and
SGLT2
What random plasma glucose level indicates diabetes? - CORRECT ANSWER - 200
What causes A1c to be falsely low? - CORRECT ANSWER - hemolytic anemia, pts taking
EPO, and AKI
How do you treat diabetic mononeuropathy (third nerve palsy)? - CORRECT ANSWER -
symptoms resolve spontaneously
How often do you screen for DM in a woman with history of gestational DM? - CORRECT
ANSWER - every year
What BP meds can be used in pregnancy? - CORRECT ANSWER - methyldopa, beta
blockers (except atenolol), CCBs, and hydralazine
What most commonly causes hypopituitarism? - CORRECT ANSWER - pituitary tumor
that applies pressure to the normal gland
How do you differentiate anterior hypopituitarism and pituitary mass? - CORRECT
ANSWER - anterior hypopituitarism will just have target organ hypofunction. HA and
vision loss suggests mass effect
What test do you need after documenting hypopituitarism or hyperprolactinemia? - CORRECT
ANSWER - MRI of the pituitary gland
, What do you measure instead of GH? - CORRECT ANSWER - IGF-1
How do you treat pituitary apoplexy? - CORRECT ANSWER - administration of
glucocorticoids until acute adrenal insufficiency has been ruled out
How do you dose thyroxine in central hypothyroidism? - CORRECT ANSWER - T4 levels
rather than TSH. Only give when hypoadrenalism has been ruled out or treated
When is the pituitary gland diffusely enlarged? - CORRECT ANSWER - untreated
hypothyroidism and during normal pregnancy
What tests do you get when a pt has hyperprolactinemia? - CORRECT ANSWER - TSH
and pregnancy test. If under 150, look at meds
What is thyrotoxicosis? - CORRECT ANSWER - occurs in destructive thyroiditis (de
Quervain), postpartum) b/c damaged thyroid releases preformed thyroid hormone . permanent
hypothyroidism may follow
How do you diagnose thyroid storm? - CORRECT ANSWER - clinical diagnosis
What do you measure if you suspect a pt is taking exogenous thyroid hormone/ - CORRECT
ANSWER - thyroglobulin levels (would be suppressed)
How do you treat Graves opthalmology? - CORRECT ANSWER - methimazole or
thyroidectomy. avoid radioactive iodine (unless pretreated with steroids)
How do you treat hyperthyroidism in pregnancy? - CORRECT ANSWER - avoid
radioactive iodine. propylthiouracil in 1st trimester, methimazole after
Metabolism UPDATED ACTUAL Exam
Questions and CORRECT Answers
What DM drugs help with weight loss? - CORRECT ANSWER - GLP-1, pramlintide, and
SGLT2
What random plasma glucose level indicates diabetes? - CORRECT ANSWER - 200
What causes A1c to be falsely low? - CORRECT ANSWER - hemolytic anemia, pts taking
EPO, and AKI
How do you treat diabetic mononeuropathy (third nerve palsy)? - CORRECT ANSWER -
symptoms resolve spontaneously
How often do you screen for DM in a woman with history of gestational DM? - CORRECT
ANSWER - every year
What BP meds can be used in pregnancy? - CORRECT ANSWER - methyldopa, beta
blockers (except atenolol), CCBs, and hydralazine
What most commonly causes hypopituitarism? - CORRECT ANSWER - pituitary tumor
that applies pressure to the normal gland
How do you differentiate anterior hypopituitarism and pituitary mass? - CORRECT
ANSWER - anterior hypopituitarism will just have target organ hypofunction. HA and
vision loss suggests mass effect
What test do you need after documenting hypopituitarism or hyperprolactinemia? - CORRECT
ANSWER - MRI of the pituitary gland
, What do you measure instead of GH? - CORRECT ANSWER - IGF-1
How do you treat pituitary apoplexy? - CORRECT ANSWER - administration of
glucocorticoids until acute adrenal insufficiency has been ruled out
How do you dose thyroxine in central hypothyroidism? - CORRECT ANSWER - T4 levels
rather than TSH. Only give when hypoadrenalism has been ruled out or treated
When is the pituitary gland diffusely enlarged? - CORRECT ANSWER - untreated
hypothyroidism and during normal pregnancy
What tests do you get when a pt has hyperprolactinemia? - CORRECT ANSWER - TSH
and pregnancy test. If under 150, look at meds
What is thyrotoxicosis? - CORRECT ANSWER - occurs in destructive thyroiditis (de
Quervain), postpartum) b/c damaged thyroid releases preformed thyroid hormone . permanent
hypothyroidism may follow
How do you diagnose thyroid storm? - CORRECT ANSWER - clinical diagnosis
What do you measure if you suspect a pt is taking exogenous thyroid hormone/ - CORRECT
ANSWER - thyroglobulin levels (would be suppressed)
How do you treat Graves opthalmology? - CORRECT ANSWER - methimazole or
thyroidectomy. avoid radioactive iodine (unless pretreated with steroids)
How do you treat hyperthyroidism in pregnancy? - CORRECT ANSWER - avoid
radioactive iodine. propylthiouracil in 1st trimester, methimazole after
