BMSC 230: Final (2025) ACTUAL EXAM
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- amino acids that are catabolized to pyruvate or an
What is a glucogenic
intermediate of the TCA cycle
amino acid?
- can be used for glucose synthesis
- amino acids that are catabolized to acetyl CoA or
acetoacetate
What is a ketogenic
- cannot give rise to the net synthesis of glucose but
amino acid?
rather lead to the formation of fatty acids, ketone
bodies, or their precursors
Which amino acids are - leucine
exclusively ketogenic? - lysine
- isoleucine
Which amino acids are - phenylalanine
both ketogenic & - tryptophane
glucogenic? - tyrosine
- threonine
- alanine
- cysteine
What amino acids are - serine
converted to pyruvate? - glycine
- threonine
- tryptophan
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Enzyme for threonine > Threonine dehydrogenase
glycine
Enzyme for glycine > Serine hydroxymethyl transferase
serine
Enzyme for serine > Serine dehydratase
pyruvate
Enzyme for alanine > Alanine aminotransferase
pyruvate
Enzyme for glutamate + Alanine aminotransferase (ALT)
pyruvate ↔ alanine + a-
ketoglutarate
Enzyme for glutamate + Aspartate aminotransferase (AST)
oxaloacetate ↔
aspartate + a-
ketoglutarate
How can serine & Serine dehydratase & threonine dehydratase
threonine be directly
deaminated to pyruvate +
NH4 & a-ketobutyrate +
NH4?
What are the coenzymes - pyridoxal
for the direct - phosphate
deamination of serine & - PLP
threonine dehydratase?
What two amino acids are - asparagine
converted to - aspartate
oxaloacetate?
Enzyme for asparagine > Asparaginase
aspartate
Enzyme for aspartate > Aspartate aminotransferase
oxaloacetate
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- glutamate
What amino acids are - glutamine
converted to a- - arginine
ketoglutarate? - histidine
- proline
Enzyme for arginine > Arginase
ornithine
What are the byproducts - H2O
of asparagine > - NH4
aspartate?
What are the byproducts - a-ketoglutarate
of aspartate > - glutamate
oxaloacetate?
What are the byproducts - H2O
of arginine > ornithine? - urea
- methionine
What amino acids are
- isoleucine
converted to succinyl
- threonine
CoA?
- valine
What are the - propionyl CoA
intermediates of - methylmalonyl CoA
methionine, valine, &
isoleucine to succinyl
CoA?
- methionine
- S-adenosylmethionine (SAM)
- S-adenosylhomocysteine
What are the steps of
- homocysteine
degradation of
- cystathionine
methionine?
- a-ketobutyrate
- propionyl CoA
- succinyl CoA
Enzyme for methionine > Methionine adenosyl transferase
S-adenosylmethionine
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