QUESTIONS AND ANSWERS 100% CORRECT!
, Naloxone (Narcan) Class - ANSWER Narcotic Antagonist
Naloxone (Narcan) MOA - ANSWER Competitive inhibition for opiate receptors
Naloxone (Narcan) Onset, Duration, Half-Life - ANSWER Onset= 1-2 mins
Duration= 30-120 mins
Half-Life= 60-90 mins
Naloxone (Narcan) Indications - ANSWER Opioid Overdose
Naloxone (Narcan) Contraindications - ANSWER Sensitivity to naloxone, nalmefene, or
naltrexone
Naloxone (Narcan) Precautions - ANSWER Pts with supraventricular arrhythmias or
other cardiac disease, head trauma/tumor
Naloxone (Narcan) Side Effects - ANSWER N/V, restlessness, diaphoresis, tachycardia,
HTN, trmors, seizures, cardiac arrest, narcotic withdrawal, combativeness
Naloxone (Narcan) Interactions - ANSWER Acute withdrawal for narcotic-dependent
patients, titrate for respiratory depression reversal
Naloxone (Narcan) Dose & Route - ANSWER Adult: 2mg (1mg per nostril) IN
0.4-2mg IV every 2-3 mins (max 10mg)
Pediatric 0.1mg/kg IN/IV every 2-3 mins (max 10mg)
Naloxone (Narcan) Pregnancy Class - ANSWER Pregnancy Class C
Ondansetron (Zofran) Class - ANSWER Antiemetic
Ondansetron (Zofran) MOA - ANSWER Serotonin receptor antagonist, blocks serotonin
receptors in chemoreceptor trigger zone (CTZ) and afferent vagal neurons in GI tract,
preventing emesis from occurring. Won't cause extrapyramidal syndrom (EPS) as it
does not interfere with dopamine receptors
Ondansetron (Zofran) Onset, Duration, Half-Life - ANSWER Onset= <30 mins
Duration= 3 hrs