1|Page
EVOLVE HESI PHARMACOLOGY EXAM
2024/2025 QS AND AS
WITH RATIONALES
A child is being treated with mebendazole for pinworms. Which type of diet
should the mother be instructed to feed the child while the child is receiving this
medication?
A. Lactose-free foods
B. High-fat diet
C. Vitamin C-enriched foods
D. High-fiber diet
B. High-fat diet
A high-fat diet increases the absorption of mebendazole, which boosts the
effectiveness of the medication in eliminating the pinworms. Options A, C, and D
are not related to the administration of this medication.
During therapy with isoniazid, it is most important for the nurse to monitor which
laboratory value closely?
A. Liver enzyme levels
B. Blood urea nitrogen (BUN) level
C. Serum electrolyte levels
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D. Complete blood count (CBC)
A. Liver enzyme levels
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The client receiving isoniazid is at risk for the development of hepatitis; therefore,
liver function test results should be monitored carefully during drug therapy.
Options B, C, and D are not specific indicators of liver function, so they are not
monitored closely during isoniazid therapy.
A client with mild parkinsonism is started on oral amantadine. Which statement
accurately describes the action of this medication?
A. Viral organisms that provide the underlyling pathophysiology for parkinsonism
are eliminated.
B. Acetylcholine in the myoneural junction is enhanced.
C. Dopamine in the central nervous system is increased.
D. Norepinephrine release is reduced within the peripheral system as the final
step in dopamine uptake.
C. Dopamine in the central nervous system is increased.
Amantadine is a dopamine-releasing agent; therefore, this medication increases
the amount of dopamine present in the central nervous system. Although this
medication is also an antiviral agent, the antiviral effect is not significant in the
treatment of parkinsonism. Options B and D are not affected by amantadine.
A client is taking famotidine. Which client statement should the nurse further
assess because it may indicate that the client is experiencing a side effect of this
drug?
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A. "I have heartburn whenever I lie down."
B. "I am never hungry. I've lost weight in the past 2 weeks."
C. "I have a funny metallic taste in my mouth."
D. "I seem to be having difficulty thinking clearly."
D. "I seem to be having difficulty thinking clearly."
A common side effect of of famotidine is confusion. Options A, B, and C are not
side effects of this medication.
A client with HIV who was recently diagnosed with tuberculosis (TB) asks the
nurse, "Why do I need to take all of these medications for TB?" What information
should the nurse provide?
A. Antiretroviral medications decrease the efficacy of the TB drugs.
B. Multiple drugs prevent the development of resistant organisms.
C. Duration of the medication regimen is shortened.
D. Potential adverse drug reactions are minimized.
B. Multiple drugs prevent the development of resistant organisms.
A multidrug regimen is prescribed for a client with HIV and TB to prevent the
development of resistance of the tubercle bacilli. Although antitubercular
medications can inhibit some antiretrovirals, a multidrug regimen is needed to
inhibit the proliferation of the virulent tubercle bacilli. The duration of
antitubercular therapy is typically 6 to 9 months and is not shortened by the use
of
EVOLVE HESI PHARMACOLOGY EXAM
2024/2025 QS AND AS
WITH RATIONALES
A child is being treated with mebendazole for pinworms. Which type of diet
should the mother be instructed to feed the child while the child is receiving this
medication?
A. Lactose-free foods
B. High-fat diet
C. Vitamin C-enriched foods
D. High-fiber diet
B. High-fat diet
A high-fat diet increases the absorption of mebendazole, which boosts the
effectiveness of the medication in eliminating the pinworms. Options A, C, and D
are not related to the administration of this medication.
During therapy with isoniazid, it is most important for the nurse to monitor which
laboratory value closely?
A. Liver enzyme levels
B. Blood urea nitrogen (BUN) level
C. Serum electrolyte levels
,2|Page
D. Complete blood count (CBC)
A. Liver enzyme levels
,3|Page
The client receiving isoniazid is at risk for the development of hepatitis; therefore,
liver function test results should be monitored carefully during drug therapy.
Options B, C, and D are not specific indicators of liver function, so they are not
monitored closely during isoniazid therapy.
A client with mild parkinsonism is started on oral amantadine. Which statement
accurately describes the action of this medication?
A. Viral organisms that provide the underlyling pathophysiology for parkinsonism
are eliminated.
B. Acetylcholine in the myoneural junction is enhanced.
C. Dopamine in the central nervous system is increased.
D. Norepinephrine release is reduced within the peripheral system as the final
step in dopamine uptake.
C. Dopamine in the central nervous system is increased.
Amantadine is a dopamine-releasing agent; therefore, this medication increases
the amount of dopamine present in the central nervous system. Although this
medication is also an antiviral agent, the antiviral effect is not significant in the
treatment of parkinsonism. Options B and D are not affected by amantadine.
A client is taking famotidine. Which client statement should the nurse further
assess because it may indicate that the client is experiencing a side effect of this
drug?
, 4|Page
A. "I have heartburn whenever I lie down."
B. "I am never hungry. I've lost weight in the past 2 weeks."
C. "I have a funny metallic taste in my mouth."
D. "I seem to be having difficulty thinking clearly."
D. "I seem to be having difficulty thinking clearly."
A common side effect of of famotidine is confusion. Options A, B, and C are not
side effects of this medication.
A client with HIV who was recently diagnosed with tuberculosis (TB) asks the
nurse, "Why do I need to take all of these medications for TB?" What information
should the nurse provide?
A. Antiretroviral medications decrease the efficacy of the TB drugs.
B. Multiple drugs prevent the development of resistant organisms.
C. Duration of the medication regimen is shortened.
D. Potential adverse drug reactions are minimized.
B. Multiple drugs prevent the development of resistant organisms.
A multidrug regimen is prescribed for a client with HIV and TB to prevent the
development of resistance of the tubercle bacilli. Although antitubercular
medications can inhibit some antiretrovirals, a multidrug regimen is needed to
inhibit the proliferation of the virulent tubercle bacilli. The duration of
antitubercular therapy is typically 6 to 9 months and is not shortened by the use
of
