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NR 507 - EDAPT - Week 6: Alterations in the Endocrine System

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NR 507 - EDAPT - Week 6: Alterations in the Endocrine System What two primary mechanisms cause significantly elevated or significantly depressed hormone levels? - ANSWER-(1) inappropriate amounts of hormones delivered to the target cell, or (2) inappropriate responses by the target cell. What causes Inappropriate amounts of hormones? 4 - ANSWER-result from disorders of endocrine glands, causing them to synthesize too little or too much hormone, failure of feedback systems designed to control hormone release, dysfunctional or ectopically produced hormones (hormones produced from nonendocrine sources), defects in the delivery of the hormone in the bloodstream. Hormone associated with posterior pituitary? - ANSWER- ADH or antidiuretic hormone What does ADH do in the body? - ANSWER-ADH is released when not enough fluid in the body. Body perceives volume depletion!! Holds onto water. Diabetes insipidus is a result of what? - ANSWER-insufficient ADH

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April 9, 2025
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NR 507 - EDAPT - Week 6: Alterations
in the Endocrine System

, What two primary mechanisms cause significantly elevated or significantly depressed
hormone levels? - ANSWER-(1) inappropriate amounts of hormones delivered to the
target cell, or
(2) inappropriate responses by the target cell.

What causes Inappropriate amounts of hormones? 4 - ANSWER-result from disorders
of endocrine glands, causing them to synthesize too little or too much hormone,
failure of feedback systems designed to control hormone release,
dysfunctional or ectopically produced hormones (hormones produced from
nonendocrine sources),
defects in the delivery of the hormone in the bloodstream.

Hormone associated with posterior pituitary? - ANSWER- ADH or antidiuretic hormone

What does ADH do in the body? - ANSWER-ADH is released when not enough fluid in
the body. Body perceives volume depletion!! Holds onto water.

Diabetes insipidus is a result of what? - ANSWER-insufficient ADH

What happens if there is insufficient ADH? - ANSWER-body can't hold onto water and
excretes: Polyuria (massive amounts).
Volume depletion (hypovolemia) - thirst mechanism is activated: polydipsia

What is neurogenic diabetes insipidus associated with - ANSWER-Traumatic brain
injuries

What is Syndrome of Inappropriate Antidiuretic Hormone (SIADH)? - ANSWER-(SIADH)
high levels of ADH secretion in the absence of normal physiological stimuli for its
release.

What is SIADH caused by? - ANSWER-ectopic secretion of ADH by several types of
tumor cells. Pulmonary disorders.
Central nervous system disorders.

What are the symptoms of SIADH? 4 - ANSWER-The symptoms result from (dilutional)
hyponatremia associated with hypervolemia (too much fluid),
high urinary sodium concentration, and weight gain.

What is the thyroid gland responsible for? - ANSWER-metabolism, growth and
development

What hormone does the hypothalamus release when T3 and T4 levels decrease? -
ANSWER-Thyroid regulating hormone (TRH)
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