Test Bank
Modern Blood Banking & Transfusion Practices 7th Edition.
By Denise M. Harmening
100% Verified Answers| Latest Edition
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All Answers Provided at the End of Each Chapter
Chapter 1: RBCs and Platelet Preservation: Historical Perspectives and Current Trends
1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
a. Pentose phosphate shunt c. Glycolysis
b. Luebering- Rapoport shunt d. Methemoglobin reductase
2. A unit of blood was returned to the blood bank before it was spiked. Apparently, the
patient’s IV failed. The unit of blood was outside the blood bank for 35 minutes. Which of the
statements below is most accurate?
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a. The unit of blood should be discarded immediately.
b.
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The unit of blood can be returned to inventory.
c. The unit of blood must be transfused within 4 hours or be discarded at the end of that
time.
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d. The unit of blood must be transfused with 24 hours.
3. What is the average diameter of a platelet?
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a. 5 to 10 µm c. 1 to 2 µm
b. 2 to 4 µm d. 4 to 6 µm
4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is
released to the tissues when PO2 averages 40 mm Hg?
a. 75% c. 100%
b. 25% d. 50%
5. What factors are known to influence platelet metabolism and function?
a. Storage temperature c. Platelet count
b. Initial pH d. All of the above
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6. Which of the following red blood cell morphologies may be present on the peripheral
blood smear as a result of loss of RBC membrane?
a. Spherocytes c. Burr cells
b. Target cells d. Schistocytes
7. What does the term autologous transfusion refer to?
a. A parent donating blood for his or her child
b. An individual donating blood for a friend
c. An individual donating blood for a relative
d. An individual donating blood for his or her own transfusion
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8. What is the primary function of hemoglobin?
a. Iron metabolism c.
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Oxygen transport
b. Porphyrin synthesis d. Signal transduction
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9. All of the following areas of red blood cell biology are crucial for normal erythrocyte
survival except:
a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. d. Hemoglobin structure.
10. What is the correct biochemical composition of the RBC membrane?
a. 52% protein, 40% lipid, 8% carbohydrate
b. 40% protein, 8% lipid, 52% carbohydrate
c. 8% protein, 52% lipid, 40% carbohydrate
d. 8% lipid, 40% carbohydrate, 52% protein
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11. All of the following biochemical changes are associated with loss of red blood cell
viability upon storage
except:
a. Decreased pH. c. Increased ATP level.
b. Loss of red blood cell function. d. Decreased glucose consumption.
12. Which red blood cell preservative has a storage time of 35 days?
a. ACD c. AS-1
b. CPDA-1 d. CPD
13. The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water.
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14. What percentage of platelets is sequestered in the spleen as functional reserve after
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being released from the bone marrow?
a. 30% c. 10%
b. 50% d. 25%
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15. What is the major biochemical consideration in platelet storage?
a. Glucose metabolism c. Production of carbon dioxide
b. Oxygen supply d. Regulation of pH
16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting
clinical signs of alkalosis?
a. Normal c. Shift to the right
b. Shift to the left d. None of the above
17. Name the main lipid components of a red blood cell membrane.
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