Identify the various routes of medication administration (Topic 1) ✔✔ 1.) Sublingual & buccal
2.) Oral (tablets, capsules; liuqids, suspensions, elixirs)
3.) Transdermal & topical
4.) Instillation (drops & sprays)
5.) Inhalation
6.) Nasogastric & gastronomy tubes
7.) Suppositories (placed in: rectum, vagina, or urethra for males)
8.) Parenteral (injections: IM, IV, SQ)
Describe basic concepts of medication safety (Topic 1) ✔✔ -The condition of being safe from
undergoing or causing hurt, injury, or loss
Apply principles of dimensional analysis to calculate medication dosages (Topic 1) ✔✔ Body
weight calculations
-Drug dose * body weight = patient's dose
--> 2.2 lb = 1 kg
Discuss the measures followed by the nurse to ensure medications are administered safely
(Topic 1) ✔✔ -6 Rights of Medication Safety
-Verify & clarify orders
Differentiate among pharmacokinetics, pharmacodynamics, and pharmacogenetics (Topic 2)
✔✔ Pharmaco-:
-Kinetics: the movement of a drug throughout the body that is necessary to achieve drug action
-Dynamics: the effect of drugs on the body
-Genetics: the genetic factors that influence an individual's response to a specific drug
, What are the drug phases for pharmacokinetics? ✔✔ -Absorption
-Distribution
-Metabolism
-Elimination
Explain the absorption phase in pharmacokinetics. ✔✔ -Drug movement from the GI tract into
the bloodstream
-Methods: passive transport (diffusion/facilitated diffusion), active transport, pinocytosis (cell
engulfs drug particles)
What are the drug phases for pharmacodynamics? ✔✔ -Receptor binding
-Postreceptor effects
-Chemical reaction
Discuss diagnostic labs and values related to pharmacokinetics associated with the liver (Topic
2) ✔✔ -Aspartate transaminase (AST): 0-35 units/L
-Alanine aminotransferase (ALT): 4-36 units/L
-Alkaline phosphate (ALP): 30-120 units/L
Discuss diagnostic labs and values related to pharmacokinetics associated with the kidneys
(Topic 2) ✔✔ -Creatanine: 0.5-1.3 mg/dL
-Blood urea nitrogen (BUN): 10-20 mg/dL
Identify the genetic considerations that my affect pharmacotherapy (Topic 2) ✔✔ -Direct
correlations between genetic makeup to a drug response, drug-drug interactions, & adverse
drug events
-Knowing the individuals specific genetic makeup can help them receive a more therapeutic
benefit & decrease the amount of adverse reactions