BIO105 UMass Amherst Final
Exam with 100% correct
answers (graded A+)
external factors impact maternal microbiome,
maternal microbiome shapes the repertoire of commensal targeting
antibodies, which cross the placenta,
SCFA's produced by mom's microbiome are transferred to the fetus,
SCFAs produced by mom's microbiome impact the development of the fetal
organs - answer Mouse studies have informed us about the impact of the
maternal microbiome on the fetus. Choose all correct statements related to
these mouse studies.
-external factors impact maternal microbiome,
-maternal microbiome shapes the repertoire of commensal targeting
antibodies, which cross the placenta,
-SCFA's produced by mom's microbiome are transferred to the fetus,
-SCFAs produced by mom's microbiome impact the development of the fetal
organs
Producing lactic acid, Producing antimicrobials, Attaching to epithelial cells to
prevent pathogen access - answer One of the primary functions of the
vaginal microbiome for the host is protective. Identify ALL of the major ways
in which this microbiome accomplishes the protection.
-Attaching to epithelial cells to prevent pathogen access
-Producing lactose to inhibit viruses
-Producing antimicrobials
-Producing hydrogen peroxide to damage host epithelial cells
,-Producing lactic acid
False - answer True or False Fecal microbiome transplant therapy has been
approved to treat C. diff infections, major depression disorder and autism
spectrum
False - answer TRUE OR FALSE Lactobacillus levels are regulated principally
by the hosts diet.
True - answer TRUE OR FALSE C-section newborns have gut microbiomes that
resemble momʼs skin microbiome and have elevated levels of hospital
microbes, while vaginal birth babies have microbiomes that resemble
primarily the mothers gut.
placenta, mode of birth, breastfeeding, furry pets - answer Which of the
following are factors known to impact a baby's microbiome development?
-placenta
-breastfeeding
-siblings diet
-furry pets
-mode of birth
True - answer True or False. The innate immune system is the bodyʼs first line
of defense. It is present at birth and lasts a lifetime.
Adaptive immune system → Develops over time as it learns to respond to
specific pathogens. Composed of B cells and T cells - the special forces of the
immune
system.,
Innate immune system → The bodyʼs first line of defense. Present at birth
and lasts a lifetime.,
, Helper T-cells → stimulate B-cells to make antibodies and help killer cells
develop.,
B-cells → A type of white blood cell that makes antibodies - answer Match
each term with the most appropriate definition.
Adaptive immune system
Innate immune system
Helper T-cells
B-cells
True - answer TRUE or FALSE Breastmilk has over 200 oligosaccharides that
cannot be digested by humans and require microbes to ferment.
Breastmilk is the only food a newborn can digest - answer Which of the
following statements about the importance of breastmilk to the developing
microbiome is incorrect.
Breastmilk contains valuable short chain fatty accids
Breastmilk is the only food a newborn can digest
Breastmilk is composed of primarily lipids, lactose, and oligosaccharides
Breastmilk is a prebiotic, as it is undigested by the human host
The correct answer is: Employ breastfeeding to help colonize the newborn's
gut microbiome - answer One way to remediate a newborn's microbiome
following c-section delivery is
Employ breastfeeding to help colonize the newborn's gut microbiome
Employ antibiotics to keep dangerous pathogens away
Limit breastfeeding to ensure the newborn is not overwhelmed with skin
microbes
Employ high fiber foods to ensure SCFAs are produced
Exam with 100% correct
answers (graded A+)
external factors impact maternal microbiome,
maternal microbiome shapes the repertoire of commensal targeting
antibodies, which cross the placenta,
SCFA's produced by mom's microbiome are transferred to the fetus,
SCFAs produced by mom's microbiome impact the development of the fetal
organs - answer Mouse studies have informed us about the impact of the
maternal microbiome on the fetus. Choose all correct statements related to
these mouse studies.
-external factors impact maternal microbiome,
-maternal microbiome shapes the repertoire of commensal targeting
antibodies, which cross the placenta,
-SCFA's produced by mom's microbiome are transferred to the fetus,
-SCFAs produced by mom's microbiome impact the development of the fetal
organs
Producing lactic acid, Producing antimicrobials, Attaching to epithelial cells to
prevent pathogen access - answer One of the primary functions of the
vaginal microbiome for the host is protective. Identify ALL of the major ways
in which this microbiome accomplishes the protection.
-Attaching to epithelial cells to prevent pathogen access
-Producing lactose to inhibit viruses
-Producing antimicrobials
-Producing hydrogen peroxide to damage host epithelial cells
,-Producing lactic acid
False - answer True or False Fecal microbiome transplant therapy has been
approved to treat C. diff infections, major depression disorder and autism
spectrum
False - answer TRUE OR FALSE Lactobacillus levels are regulated principally
by the hosts diet.
True - answer TRUE OR FALSE C-section newborns have gut microbiomes that
resemble momʼs skin microbiome and have elevated levels of hospital
microbes, while vaginal birth babies have microbiomes that resemble
primarily the mothers gut.
placenta, mode of birth, breastfeeding, furry pets - answer Which of the
following are factors known to impact a baby's microbiome development?
-placenta
-breastfeeding
-siblings diet
-furry pets
-mode of birth
True - answer True or False. The innate immune system is the bodyʼs first line
of defense. It is present at birth and lasts a lifetime.
Adaptive immune system → Develops over time as it learns to respond to
specific pathogens. Composed of B cells and T cells - the special forces of the
immune
system.,
Innate immune system → The bodyʼs first line of defense. Present at birth
and lasts a lifetime.,
, Helper T-cells → stimulate B-cells to make antibodies and help killer cells
develop.,
B-cells → A type of white blood cell that makes antibodies - answer Match
each term with the most appropriate definition.
Adaptive immune system
Innate immune system
Helper T-cells
B-cells
True - answer TRUE or FALSE Breastmilk has over 200 oligosaccharides that
cannot be digested by humans and require microbes to ferment.
Breastmilk is the only food a newborn can digest - answer Which of the
following statements about the importance of breastmilk to the developing
microbiome is incorrect.
Breastmilk contains valuable short chain fatty accids
Breastmilk is the only food a newborn can digest
Breastmilk is composed of primarily lipids, lactose, and oligosaccharides
Breastmilk is a prebiotic, as it is undigested by the human host
The correct answer is: Employ breastfeeding to help colonize the newborn's
gut microbiome - answer One way to remediate a newborn's microbiome
following c-section delivery is
Employ breastfeeding to help colonize the newborn's gut microbiome
Employ antibiotics to keep dangerous pathogens away
Limit breastfeeding to ensure the newborn is not overwhelmed with skin
microbes
Employ high fiber foods to ensure SCFAs are produced
