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One of the most common adverse effects seen in patients with ______ alcoholism is
alcoholic neuropathy. - ANSWER-chronic
Sensory symptoms often present _____ in alcoholic neuropathy. The first clue may be
_____ on the soles followed by dysesthesia on the feet. - ANSWER-early
numbness
Activation of the sympathetic system by LSD causes:
- _______ blood pressure
- piloerection
- _____cardia
- __________ body temperature
- pupillary _______ - ANSWER-elevated
tachy
elevated
dilation
________- is known to cause vivid hallucinations with bright colors and geometric
objects. - ANSWER-LSD
Flashbacks are associated with ______ use - ANSWER-LSD
A 25-year-old female is being admitted to a residential treatment facility for alcohol use
disorder. Her last drink was 12 hours ago. On admission, medication reconciliation is
performed and it is discovered she is taking bupropion for smoking cessation, sertraline
for depression, and ibuprofen as needed for headaches. Which of the following is the
most appropriate recommendation regarding the patient's medications at this time? -
ANSWER-Discontinue bupropion only.
Bupropion can only be administered _____
Injection of dissolved bupropion can result in ____ and death - ANSWER-orally.
seizure
Bupropion should be used with caution in patients with: - ANSWER-- CVD
- HTN
- CAD
,Cognitive-behavioral groups are useful for changing what? - ANSWER-beliefs and
perceptions
This questionnaire is an introspective self-report questionnaire claiming to indicate
psychological preferences in how people make decisions and perceive the world around
them. - ANSWER-The Myers-Briggs Type Indicator (MBTI) assessment
Routine urine screens do not detect
- ______ cannabinoids
- _______
- _______
- chemical variants of ______
- _____ - ANSWER-synthetic
MDMA
ecstasy
opioids
PCP
Positive drug screens in patients without clinical symptoms may reflect the detection of
________ and previous use - ANSWER-metabolites
What is the name of an acute neurological condition characterized by a clinical triad of:
1. ophthalmoparesis with nystagmus
2. gait ataxia
3. confusion - ANSWER-Wernicke encephalopathy (WE)
What 3 drug substances are approved by the FDA for MAT? - ANSWER-Alcohol,
Opioid, Nicotine
A 57-year-old man with a longstanding history of alcohol use presents with confusion,
disorientation, and gait imbalance. Other than disorientation, bilateral paresis of
conjugate gaze is noted. CT head is negative. Which vitamin deficiency is most likely? -
ANSWER-Thiamine (B1)
What medication used in AUD inhibits ALDH? - ANSWER-Disulfiram
Disulfiram action causes an excess of what enzyme?
This enzyme has a vasodilatory effect that causes: - ANSWER-Acetaldehyde
tachycardia and hypotension.
4 NTs associated with drinking are - ANSWER-Glutamate
GABA
Dopamine
Endogenous opioids
When alcohol is consumed there is a release of
, ___________ ________, then _______ ,which makes the drinker feel good.
AT THE SAME TIME
alcohol has an effect on ______ receptors; they are are increased (sedation effect)
The areas of the brain most often affected by Wernicke Korsakoff syndrome are where?
- ANSWER-1. thalamus
2. mammillary bodies
3. corpus callosum
The individual with Wernicke Korsakoff syndrome will usually present with ocular
disturbances which may include: - ANSWER-- diplopia
- painless vision loss
- strabismus
What causes Wernicke-Korsakoff syndrome? - ANSWER-thiamine deficiency
Korsakoff's syndrome is the reversible stage of Wernicke-Korsakoff syndrome
T or F - ANSWER-False; irreversible
Korsokoff's Syndrome- an alcohol related disorder marked by extreme ________ and
_______ impairment
________ is a fundamental neuropsychiatric symptom of the disorder - ANSWER-
confusion
memory
apathy
To start methadone treatment, the patient must be on opioids for at least ___ months,
unless what? - ANSWER-12
Pregnancy is an exception to this criteria, even if the use of opioids is less than a year.
What is the maximum dose of methadone for the worst withdrawal symptoms?
What is the initial dosage for everyone else (i.e. used by most clinics) - ANSWER-40 mg
30 mg
In the liver, an enzyme called ________ __________ converts alcohol to
what__________ - ANSWER-alcohol dehydrogenase (ADH)
acetaldehyde.
ALDH converts acetaldehyde to - ANSWER-Acetate