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Davis Edge Week 7
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Q
Question 1. Lorie, age 29, appears with the following signs: pale conjunctivae and
nailbeds, tachycardia, heart murmur, cheilosis, stomatitis, splenomegaly, koilonychia, a
glossitis. What do you suspect?
1. Vitamin B12 deficiency
2. Folate deficiency
3. Iron-deficiency anemia
4. Chronic fatigue syndrome
Rationales
Option 1: Signs of vitamin B12 deficiency include weakness of the extremities, ataxia, pallor, loss of vibrato
loss, changes in mood, and hallucinations.
Option 2: Signs of a folate deficiency include weakness, pallor, and glossitis, with congestive heart failure
severe.
Option 3: Lorie has the classic signs of iron-deficiency anemia: pale conjunctivae and nailbeds, tachycard
(reddened lips with fissures at the angles), stomatitis, splenomegaly, koilonychia (thin and concave fingerna
glossitis. Signs may also include esophageal webs (Plummer-Vinson syndrome), melena, and menorrhagia.
Option 4: A person with chronic fatigue syndrome might have a fever, a sore throat, myalgia, and generaliz
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Course Topic: Hematologic and Immune Problems | Area of Practice: Adult-Gerontology Primary Care, F
APN Knowledge Area: Health Assessment | Testing Domain: Assess | Cognitive Level: Analysis [Ana
Question 2. Jimmy, age 6 months, is newly diagnosed with sickle cell disease. His
, 3/1/25, 9:03 PM Feedback
pneumococcal vaccine at age 2 years. There is no cure for sickle cell disease.
Option 4: Jimmy should receive all the standard immunizations, and he should receive the pneumococcal
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Course Topic: Hematologic and Immune Problems | Area of Practice: Family Practice, Pediatrics | AP
Promotion and Patient Education, Population Health and Epidemiology, Disease Management | Testing D
Cognitive Level: Application [Applying]
Question 3. Your patient Shirley has an elevated mean corpuscular volume (MCV). W
should you be considering in terms of diagnosis?
1. Iron-deficiency anemias
2. Hemolytic anemias
3. Lead poisoning
4. Liver disease
Rationales
Option 1: The MCV is decreased (microcytic) in iron-deficiency anemias.
Option 2: The MCV is decreased (microcytic) in hemolytic anemias.
Option 3: The MCV is decreased (microcytic) in defects involving porphyrin synthesis, such as those cause
Option 4: The MCV indicates the average size of individual red blood cells. The normal (normocytic) range
increased (macrocytic) in megaloblastic anemias (i.e., vitamin B12 deficiency and folate deficiency) and liver
from alcohol abuse), as well as with the use of some drugs (e.g., zidovudine).
[Page Reference: 1080]
Course Topic: Hematologic and Immune Problems | Area of Practice: Pediatrics, Adult-Gerontology Prim
APN Knowledge Area: Differential Diagnosis Clinical Decision-Making, Diagnostic Tests and Therapeutic Pr
Diagnose | Cognitive Level: Analysis [Analyzing]
Question 4. Which is the best serum test for spotting an iron deficiency early, before
progresses to full-blown anemia?