Breast pathology ARDMS questions with verified
answers
___ have an increased incidence of this focal fibrosis Ans✓✓✓ Disbetics
___ more common than cysts in women in 30 Ans✓✓✓ Fibroadenoma
___ used to confirm diagnosis of diabetic fibrosis Ans✓✓✓ Biopsy
___ women have the highest mortality rate Ans✓✓✓ African American
______ responsible for nearly 50% of all surgical procedures performed on the
breast Ans✓✓✓ Fibrocystic disease
_% of breast cancer patients have a family history of the disease Ans✓✓✓ <25%
(IDC) normal ductal cells undergo hyperplasia then Ans✓✓✓ DCIS forms
DCIS progresses to invasive ductal Carcinoma and then metastasis occurs
Desmoplasia - host response of reactive fibrosis of surrounding tissues; body
trying to put up a "wall" of fibrous tissues around the tumor, a hall of thickened
tissue forms around the mass
#1 risk fact for breast cancer Ans✓✓✓ Gender
,100 times more common in women
#2 risk factor for breast cancer Ans✓✓✓ Age
75-80% breast cancer seen in women over 50
#3 risk factor for breast cancer Ans✓✓✓ Family history
Having a single first degree relative with breast cancer doubles the risk of patient
developing breast cancer
Having two first degree relatives with breast cancer increases the risk of patient
developing breast cancer by a factor of 5
<25% have a first or second degree relative with history of breast ca
Personal history of CA increases risk by a factor of 4
10% of patients with breast cancer have Ans✓✓✓ BRCA gene 1 and 2 mutation
2nd most common breast cancer overall Ans✓✓✓ DCIS or intraductal Carcinoma
,80% of breast cancer occurs in women Ans✓✓✓ Over 50
Rarely occurs before age 30
Abscess Ans✓✓✓ Contains pus, WBC
Color doppler will display an increase in flow along the periphery of the cyst
Abscess most commonly found Ans✓✓✓ In the subareolar region of the breast
Acorn cyst Ans✓✓✓ Mural nodule or eccentrically thickened wall caused by
PAM, cyst appears to have a cap like and acorn
Acute mastitis is treated by Ans✓✓✓ Antibiotic therapy
Acute mastitis may result from Ans✓✓✓ Infection
Trauma
Post surgery
Mechanical duct obstruction
, May also occur diffusely due to infection carried via blood or lymphatics
Acute mastitis usually occurs during Ans✓✓✓ Lactation (puerperal)
Additional risks Ans✓✓✓ Postmenopausal obesity
Nulliparity or pregnancy after age 30
Prolonged use of HRT (estrogen) or oral contraceptives
Radiation therapy to chest
Li-fraumeni syndrome- rare autosomal dominant disorder that greatly increases
the risk of developing several types of cancer
Cowden syndrome- rare autosomal dominant disorder characterized by multiple
hamartoma and an increased risk of developing certain cancers
Atypical ductal hyperplasia (ADH) 4-5 times risk than that of general population
Adenosis is considered Ans✓✓✓ A part of fibrocystic breast disease
Benign breast changes that mimic invasive carcinoma Ans✓✓✓ Scar tissue
answers
___ have an increased incidence of this focal fibrosis Ans✓✓✓ Disbetics
___ more common than cysts in women in 30 Ans✓✓✓ Fibroadenoma
___ used to confirm diagnosis of diabetic fibrosis Ans✓✓✓ Biopsy
___ women have the highest mortality rate Ans✓✓✓ African American
______ responsible for nearly 50% of all surgical procedures performed on the
breast Ans✓✓✓ Fibrocystic disease
_% of breast cancer patients have a family history of the disease Ans✓✓✓ <25%
(IDC) normal ductal cells undergo hyperplasia then Ans✓✓✓ DCIS forms
DCIS progresses to invasive ductal Carcinoma and then metastasis occurs
Desmoplasia - host response of reactive fibrosis of surrounding tissues; body
trying to put up a "wall" of fibrous tissues around the tumor, a hall of thickened
tissue forms around the mass
#1 risk fact for breast cancer Ans✓✓✓ Gender
,100 times more common in women
#2 risk factor for breast cancer Ans✓✓✓ Age
75-80% breast cancer seen in women over 50
#3 risk factor for breast cancer Ans✓✓✓ Family history
Having a single first degree relative with breast cancer doubles the risk of patient
developing breast cancer
Having two first degree relatives with breast cancer increases the risk of patient
developing breast cancer by a factor of 5
<25% have a first or second degree relative with history of breast ca
Personal history of CA increases risk by a factor of 4
10% of patients with breast cancer have Ans✓✓✓ BRCA gene 1 and 2 mutation
2nd most common breast cancer overall Ans✓✓✓ DCIS or intraductal Carcinoma
,80% of breast cancer occurs in women Ans✓✓✓ Over 50
Rarely occurs before age 30
Abscess Ans✓✓✓ Contains pus, WBC
Color doppler will display an increase in flow along the periphery of the cyst
Abscess most commonly found Ans✓✓✓ In the subareolar region of the breast
Acorn cyst Ans✓✓✓ Mural nodule or eccentrically thickened wall caused by
PAM, cyst appears to have a cap like and acorn
Acute mastitis is treated by Ans✓✓✓ Antibiotic therapy
Acute mastitis may result from Ans✓✓✓ Infection
Trauma
Post surgery
Mechanical duct obstruction
, May also occur diffusely due to infection carried via blood or lymphatics
Acute mastitis usually occurs during Ans✓✓✓ Lactation (puerperal)
Additional risks Ans✓✓✓ Postmenopausal obesity
Nulliparity or pregnancy after age 30
Prolonged use of HRT (estrogen) or oral contraceptives
Radiation therapy to chest
Li-fraumeni syndrome- rare autosomal dominant disorder that greatly increases
the risk of developing several types of cancer
Cowden syndrome- rare autosomal dominant disorder characterized by multiple
hamartoma and an increased risk of developing certain cancers
Atypical ductal hyperplasia (ADH) 4-5 times risk than that of general population
Adenosis is considered Ans✓✓✓ A part of fibrocystic breast disease
Benign breast changes that mimic invasive carcinoma Ans✓✓✓ Scar tissue
