NAPSRX EXAM QUESTIONS WITH
COMPLETE ANSWERS
Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - Answer-false
Legally, bioequivalence of different versions of a drug can vary by up to ________. -
Answer-20%
which of the following statements about biologics is incorrect - Answer-they do not
cause immune response
"large molecules" products are developed and manufactured by a chemical process -
Answer-false
what are drugs that attract or bind to cell receptors in order to mimic or enhance
activities by endogenous chemical messengers - Answer-agonists
Which term denotes how an API works in the body? - Answer-mechanism of action
What cements the active and inert components together to maintain cohesive
portions? - Answer-binders
what does the medical abbreviation "BID" denote - Answer-twice a day
what is the medical abbreviation for "as needed" - Answer-PRN
what components might cause patients' different reactions to brand name and
generic drugs - Answer-differences in inactive ingredients
all cells have a nucleus - Answer-false
which of the following does not affect drug response - Answer-the patients' genetic
makeup, age, body size, and use of other drugs and dietary supplements, the
patient's other conditions or diseases, whether or not the patient takes the drug
properly
drug reactions are predictable because they do not occur after a person has been
previously exposed to the drug one or more times without any allergic reactions -
Answer-false
what is the typical relationship between a drug's site of administration and site of
action - Answer-they are usually somewhat removed from each other
what is CMAX - Answer-Peak plasma concentration on a measuring curve
which of the following is not a main concept in clinical pharmacology - Answer-
pharmacoprocesses
,which of the following is not a route of drug administration - Answer-transfugal
How are intradermal drugs delivered? - Answer-by injection under the skin
what is an example of intravenous drug delivery - Answer-an injection of anesthetic
directly into the bloodstream
what are the major organs of the gastrointestinal system - Answer-the mouth,
esophagus, stomach, liver, pancreas, gallbladder, small intestine, large intestine
who is normally responsible for selling to distributors - Answer-NAMs
How often do secondary drug wholesale distributors buy their drugs directly from
manufactures? - Answer-sometimes
By FDA law, large chain pharmacies are not allowed to buy directly from drug
manufactures. - Answer-false
Only 3 companies account for nearly 90% of all drug wholesale sales. - Answer-true
what type of sale bypasses the need for intermediary distributors - Answer-
manufacturer- direct sales
what is a group purchasing organization (GPO) - Answer-an entity consisting of two
or more hospitals or other health care entities that negotiates contracts on behalf of
its members
what will you find the legend "Caution: federal law prohibits dispensing without a
prescription - Answer-on the label of all prescription drugs
what happens to slow acetylators - Answer-Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain in the body longer.
About ___ of the people in the U.S. are "slow acetylators" - Answer-50%
which of the following statements about drug-drug interactions is incorrect - Answer-
drug-drug interactions are always harmful
Smoking decreases the effectiveness of some drugs - Answer-true
which of the following statements about dietary supplements is incorrect - Answer-
because dietary supplements are not drugs, interactions with drugs are not a
concern
which statement/s is/are incorrect about an ideal drug, or "magic bullet" as Ehrlich
phrased it - Answer-it does not exist, it would be aimed precisely at a disease site, it
would not harm healthy tissues
, which statement accurately differentiates resistance from tolerance - Answer-
tolerance refers to a person's diminished response to a drug after repeated use,
while resistance applies to microorganisms' or "cancel" cells' abilities to withstand
drug effects
between 3% and 7% of hospital admissions in the United States are estimated to be
for treatment of adverse drug reactions - Answer-true
which statement is true about the universal scale for quantifying the severity of an
adverse drug reaction - Answer-there is no scale
why is noncompliance a serios public healthy concern - Answer-it increases the cost
of medical care
which of the following is NOT eligible for patent protection under U.S. regulations -
Answer-companies can be granted patents for all these things
drugs' trade names are often unrelated to their intended use - Answer-true
Prescriptions dispensed by mail-order pharmacies are, on average, around
____________ than those dispensed by retail pharmacies. - Answer-3 times larger
which of the following is not a type of non-stock sale - Answer-brokerage sales,
dock-to-dock sales, drop shipments
what is another term for rebates - Answer-after-market arrangements
the PDMA is the prescription drug manufacturers association - Answer-false
a company that owns and operates three or fewer pharmacies is an - Answer-
independent drug store
which section of a drug's package insert information covers the usual dosage range -
Answer-indications and usage
Drug labels must include indications and usage information, as well as
contraindications. - Answer-true
what should be included in the "description" section off a drug's package insert
information - Answer-the drug's proprietary name and the established name
Exclusivity gives exclusive _____, is granted by the FDA, and can run concurrently
with a patent or not. - Answer-marketing rights
what differentiates exclusivity from a patent - Answer-Exclusivity is only granted
upon the drug's FDA approval.
what is required of an invention for it to be worthy of patent protection - Answer-it
must be novel, useful, and not obvious
COMPLETE ANSWERS
Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - Answer-false
Legally, bioequivalence of different versions of a drug can vary by up to ________. -
Answer-20%
which of the following statements about biologics is incorrect - Answer-they do not
cause immune response
"large molecules" products are developed and manufactured by a chemical process -
Answer-false
what are drugs that attract or bind to cell receptors in order to mimic or enhance
activities by endogenous chemical messengers - Answer-agonists
Which term denotes how an API works in the body? - Answer-mechanism of action
What cements the active and inert components together to maintain cohesive
portions? - Answer-binders
what does the medical abbreviation "BID" denote - Answer-twice a day
what is the medical abbreviation for "as needed" - Answer-PRN
what components might cause patients' different reactions to brand name and
generic drugs - Answer-differences in inactive ingredients
all cells have a nucleus - Answer-false
which of the following does not affect drug response - Answer-the patients' genetic
makeup, age, body size, and use of other drugs and dietary supplements, the
patient's other conditions or diseases, whether or not the patient takes the drug
properly
drug reactions are predictable because they do not occur after a person has been
previously exposed to the drug one or more times without any allergic reactions -
Answer-false
what is the typical relationship between a drug's site of administration and site of
action - Answer-they are usually somewhat removed from each other
what is CMAX - Answer-Peak plasma concentration on a measuring curve
which of the following is not a main concept in clinical pharmacology - Answer-
pharmacoprocesses
,which of the following is not a route of drug administration - Answer-transfugal
How are intradermal drugs delivered? - Answer-by injection under the skin
what is an example of intravenous drug delivery - Answer-an injection of anesthetic
directly into the bloodstream
what are the major organs of the gastrointestinal system - Answer-the mouth,
esophagus, stomach, liver, pancreas, gallbladder, small intestine, large intestine
who is normally responsible for selling to distributors - Answer-NAMs
How often do secondary drug wholesale distributors buy their drugs directly from
manufactures? - Answer-sometimes
By FDA law, large chain pharmacies are not allowed to buy directly from drug
manufactures. - Answer-false
Only 3 companies account for nearly 90% of all drug wholesale sales. - Answer-true
what type of sale bypasses the need for intermediary distributors - Answer-
manufacturer- direct sales
what is a group purchasing organization (GPO) - Answer-an entity consisting of two
or more hospitals or other health care entities that negotiates contracts on behalf of
its members
what will you find the legend "Caution: federal law prohibits dispensing without a
prescription - Answer-on the label of all prescription drugs
what happens to slow acetylators - Answer-Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain in the body longer.
About ___ of the people in the U.S. are "slow acetylators" - Answer-50%
which of the following statements about drug-drug interactions is incorrect - Answer-
drug-drug interactions are always harmful
Smoking decreases the effectiveness of some drugs - Answer-true
which of the following statements about dietary supplements is incorrect - Answer-
because dietary supplements are not drugs, interactions with drugs are not a
concern
which statement/s is/are incorrect about an ideal drug, or "magic bullet" as Ehrlich
phrased it - Answer-it does not exist, it would be aimed precisely at a disease site, it
would not harm healthy tissues
, which statement accurately differentiates resistance from tolerance - Answer-
tolerance refers to a person's diminished response to a drug after repeated use,
while resistance applies to microorganisms' or "cancel" cells' abilities to withstand
drug effects
between 3% and 7% of hospital admissions in the United States are estimated to be
for treatment of adverse drug reactions - Answer-true
which statement is true about the universal scale for quantifying the severity of an
adverse drug reaction - Answer-there is no scale
why is noncompliance a serios public healthy concern - Answer-it increases the cost
of medical care
which of the following is NOT eligible for patent protection under U.S. regulations -
Answer-companies can be granted patents for all these things
drugs' trade names are often unrelated to their intended use - Answer-true
Prescriptions dispensed by mail-order pharmacies are, on average, around
____________ than those dispensed by retail pharmacies. - Answer-3 times larger
which of the following is not a type of non-stock sale - Answer-brokerage sales,
dock-to-dock sales, drop shipments
what is another term for rebates - Answer-after-market arrangements
the PDMA is the prescription drug manufacturers association - Answer-false
a company that owns and operates three or fewer pharmacies is an - Answer-
independent drug store
which section of a drug's package insert information covers the usual dosage range -
Answer-indications and usage
Drug labels must include indications and usage information, as well as
contraindications. - Answer-true
what should be included in the "description" section off a drug's package insert
information - Answer-the drug's proprietary name and the established name
Exclusivity gives exclusive _____, is granted by the FDA, and can run concurrently
with a patent or not. - Answer-marketing rights
what differentiates exclusivity from a patent - Answer-Exclusivity is only granted
upon the drug's FDA approval.
what is required of an invention for it to be worthy of patent protection - Answer-it
must be novel, useful, and not obvious
