NAPSR/CNPR EXAM QUESTIONS WITH
VERIFIED ANSWERS
Representatives are required to store samples in a secure area where people cannot
access them without permission and where they will not be subjected to extremes of
temperature, moisture, and contamination - Answer-True
A sample closet or cabinet is essentially similar to a grocery store shelf. The more
visibility you can give your drug, the more likely it will be used. - Answer-True
In some situations, a physician may sign the paperwork before the number of
samples has been recorded - Answer-True
Section 503 - Answer-Prohibits sale, purchase, or trade of drug samples
E-sampling - Answer-Pg 72
Many pharmaceutical manufacturers set expiration dates every six months (June,
December) - Answer-True
DEA regulates the distribution and use of narcotics and other controlled substances -
Answer-True
FTC - Answer-Regulates general business practices to protect consumers against
misleading claims and anticompetitive behavior
AMA - Answer-provides ethical guidelines to physicians about appropriate
interactions with pharmaceutical companies
Benefits of Government-Industry Partnerhsips - Answer-Pg 79
Preclinical studies - Answer-pg 81
Pinocytosis - Answer-Involves the engulfing of fluids by a cell.
Transport Mechanisms - Answer-Passive diffusion, facilitated diffusion, active
transport, pinocytosis
Absorption methods - Answer-Oral, Buccal, sublingual, rectal, subcutaneous,
intramuscular, transdermal, topical, inhalation, intravenous
The liver is the major organ for metabolizing drugs. Secondary is kidney - Answer-
True
CL= rate of drug elimination/drug concentration in blood - Answer-True
In vitro assays are increasingly being see because they are usually less expensive,
offer more rapid results, and are not as prone to negative publicity. - Answer-True
, Clinical Trials - Answer-pg 89
Subjects should be informed about the aims, methods, risks, and benefits of the trial
- Answer-True
Four phases of clinical trials - Answer-Pg 90
Regulatory Requirement terms - Answer-Pg 92
Investigator - Answer-The person who conducts the trial. This person is normally an
expert in the field. They should not be employed by the sponsor
Sponsor - Answer-The organization or individual that initiates the trial and finances
the study,
Protocol - Answer-This document sets out how a trial is to be conducted
Epidemiology - Answer-The study of how factors influence disease and health in
human populations.
Therapeutic - Answer-Antibodies
Vaccines - Answer-Pg 108
Toxoids - Answer-Derived from toxins secreted by a pathogen.Examples are
diphtheria and tetnus vaccines.
Vector-based vaccines - Answer-Viruses and bacteria are detoxified and used as
vehicles to carry vaccines. Example is the use of canary pox (a virus that infects
birds but not humans) to carry envelope proteins for HIV treatment.
Peptide Vaccines - Answer-Chemically synthesized and normally consist of 8-24
amino acids
Adjuvants - Answer-pg 110
Cytokines are produced mainly by the leukocytes (white blood cells) - Answer-True
Hormones are intercellular messengers. - Answer-True
Retrovirus - Answer-Integrates genes to hose chromosomes, change of long term
stability.
Adendovirus - Answer-This vector has a large capacity for foreign genes.
Liposomes - Answer-Vector does not have viral genes so they do not cause disease.
Naked DNA - Answer-they do not have viral genes and do not cause disease
VERIFIED ANSWERS
Representatives are required to store samples in a secure area where people cannot
access them without permission and where they will not be subjected to extremes of
temperature, moisture, and contamination - Answer-True
A sample closet or cabinet is essentially similar to a grocery store shelf. The more
visibility you can give your drug, the more likely it will be used. - Answer-True
In some situations, a physician may sign the paperwork before the number of
samples has been recorded - Answer-True
Section 503 - Answer-Prohibits sale, purchase, or trade of drug samples
E-sampling - Answer-Pg 72
Many pharmaceutical manufacturers set expiration dates every six months (June,
December) - Answer-True
DEA regulates the distribution and use of narcotics and other controlled substances -
Answer-True
FTC - Answer-Regulates general business practices to protect consumers against
misleading claims and anticompetitive behavior
AMA - Answer-provides ethical guidelines to physicians about appropriate
interactions with pharmaceutical companies
Benefits of Government-Industry Partnerhsips - Answer-Pg 79
Preclinical studies - Answer-pg 81
Pinocytosis - Answer-Involves the engulfing of fluids by a cell.
Transport Mechanisms - Answer-Passive diffusion, facilitated diffusion, active
transport, pinocytosis
Absorption methods - Answer-Oral, Buccal, sublingual, rectal, subcutaneous,
intramuscular, transdermal, topical, inhalation, intravenous
The liver is the major organ for metabolizing drugs. Secondary is kidney - Answer-
True
CL= rate of drug elimination/drug concentration in blood - Answer-True
In vitro assays are increasingly being see because they are usually less expensive,
offer more rapid results, and are not as prone to negative publicity. - Answer-True
, Clinical Trials - Answer-pg 89
Subjects should be informed about the aims, methods, risks, and benefits of the trial
- Answer-True
Four phases of clinical trials - Answer-Pg 90
Regulatory Requirement terms - Answer-Pg 92
Investigator - Answer-The person who conducts the trial. This person is normally an
expert in the field. They should not be employed by the sponsor
Sponsor - Answer-The organization or individual that initiates the trial and finances
the study,
Protocol - Answer-This document sets out how a trial is to be conducted
Epidemiology - Answer-The study of how factors influence disease and health in
human populations.
Therapeutic - Answer-Antibodies
Vaccines - Answer-Pg 108
Toxoids - Answer-Derived from toxins secreted by a pathogen.Examples are
diphtheria and tetnus vaccines.
Vector-based vaccines - Answer-Viruses and bacteria are detoxified and used as
vehicles to carry vaccines. Example is the use of canary pox (a virus that infects
birds but not humans) to carry envelope proteins for HIV treatment.
Peptide Vaccines - Answer-Chemically synthesized and normally consist of 8-24
amino acids
Adjuvants - Answer-pg 110
Cytokines are produced mainly by the leukocytes (white blood cells) - Answer-True
Hormones are intercellular messengers. - Answer-True
Retrovirus - Answer-Integrates genes to hose chromosomes, change of long term
stability.
Adendovirus - Answer-This vector has a large capacity for foreign genes.
Liposomes - Answer-Vector does not have viral genes so they do not cause disease.
Naked DNA - Answer-they do not have viral genes and do not cause disease
