NURS 210 Exam 2: Coagulation Modifiers
Questions and Answers 100% Correct
Vascular purpura a vascular disorder: Non-blanching lesions are present - an abnormality
of the vessel or supporting tissues
Examples of disorders include:
-drug-induced
-allergic reaction
-scurvy
-senile purpura
-steroid use
Treatment is to remove the causative agent
Hereditary hemorrhagic telangiectasia: An abnormality in vascular development due to a
genetic disorder
Usually seen in children
Clinical manifestations include:
-bright red and purple lesions
,-recurrent nose bleeds
Thrombocytopenia: A condition where you have a low platelet count (<50,000)
Can occur at any age and usually caused by an INFECTION
Will see low platelet count on CBC
Drugs that induce thrombocytopenia: Drugs can cause antigen-antibody reactions that
result in the destruction to platelets
Ex: Sulfa, heparin, quinidine
Thrombocytosis: A condition where you have high platelet counts (>750,000)
Can occur due to:
-hemorrhage
-inflammation
-malignancy
-infection
-hemolysis
, -SPLENECTOMY (because the spleen sequesters and lyses dead platelets)
Two types of thrombocytosis: Primary/essential thrombocytosis occurs from the bone
marrow and cause is unknown
Secondary thrombocytosis is caused by another primary condition such as anemia, cancer,
inflammation
Coagulation disorders - Hemophilia: Most common and severe inherited coagulation
disorder
Two types
Both types are X-linked, recessive disorders that primarily affect males
Bleeding is the common clinical manifestation
Treatment: Cryoprecipitate which is prepared from plasma and contains fibrinogen, von
Willebrand factor, factor VIII, factor XIII and fibronectin
Hemophilia A: Caused by a deficiency in factor VIII
Most common form (80%) of cases
Questions and Answers 100% Correct
Vascular purpura a vascular disorder: Non-blanching lesions are present - an abnormality
of the vessel or supporting tissues
Examples of disorders include:
-drug-induced
-allergic reaction
-scurvy
-senile purpura
-steroid use
Treatment is to remove the causative agent
Hereditary hemorrhagic telangiectasia: An abnormality in vascular development due to a
genetic disorder
Usually seen in children
Clinical manifestations include:
-bright red and purple lesions
,-recurrent nose bleeds
Thrombocytopenia: A condition where you have a low platelet count (<50,000)
Can occur at any age and usually caused by an INFECTION
Will see low platelet count on CBC
Drugs that induce thrombocytopenia: Drugs can cause antigen-antibody reactions that
result in the destruction to platelets
Ex: Sulfa, heparin, quinidine
Thrombocytosis: A condition where you have high platelet counts (>750,000)
Can occur due to:
-hemorrhage
-inflammation
-malignancy
-infection
-hemolysis
, -SPLENECTOMY (because the spleen sequesters and lyses dead platelets)
Two types of thrombocytosis: Primary/essential thrombocytosis occurs from the bone
marrow and cause is unknown
Secondary thrombocytosis is caused by another primary condition such as anemia, cancer,
inflammation
Coagulation disorders - Hemophilia: Most common and severe inherited coagulation
disorder
Two types
Both types are X-linked, recessive disorders that primarily affect males
Bleeding is the common clinical manifestation
Treatment: Cryoprecipitate which is prepared from plasma and contains fibrinogen, von
Willebrand factor, factor VIII, factor XIII and fibronectin
Hemophilia A: Caused by a deficiency in factor VIII
Most common form (80%) of cases
