1 Exampromax - Stuvia US 2025/2026
Usmle Step 1 First Aid Questions with Detailed Verified
Answers (100% Correct Answers) /Already Graded A+
polyostotic fibrous dysplasia, precocious puberty, cafe-au-lait spots, short
stature, young girls - diagnosis?
Ans: Albright's syndrome
blue-domed cysts - diagnosis?
Ans: fibrocystic change of the breast
Wermer's syndrome - also known as?
Ans: MEN type I
Exampromax - Stuvia US
"wire loop" appearance on Light microscopy- diagnosis?
Approved By:
Ans: lupus nephropathy
what is the defect in Job's syndrome?
Ans: neutrophil chemotaxis abnormality - due to failure of IFN-gamma
production by helper T cells
xanthochromia of CSF - diagnosis?
Ans: subarachnoid hemorrhage
4 most common brain tumors in adults
Ans: mets > astrocytoma (including glioblastoma multiforme) >
meningioma > schwannoma
most common supratentorial brain tumor in kids
Ans: craniopharyngioma
most common bug in debilitated, hospitalized pneumonia patient
, 2 Exampromax - Stuvia US 2025/2026
Ans: Klebsiella
pseudopalisade tumor cell arrangement - diagnosis?
Ans: glioblastoma multiforme
pseudorosettes - diagnosis?
Ans: Tumour(Ewing's sarcoma)
nutmeg liver - diagnosis?
Ans: CHF
"Orphan Annie" nuclei - diagnosis?
Exampromax - Stuvia US
Ans: papillary carcinoma of the thyroid
Approved By:
painless jaundice - diagnosis?
Ans: pancreatic cancer (of head)
most common liver disease
Ans: alcoholic liver disease
"brown tumor" of bone - possible diagnoses?
- what causes the brown color?
Ans: hyperparathyroidism or osteitis fibrosa cystica (von Recklinghausen's
disease)
- color is due to hemorrhage in cysts
renal epithelial casts in urine - diagnosis?
Ans: acute toxic/viral nephrosis
most common location of brain tumors in kids
Ans: infratentorial
, 3 Exampromax - Stuvia US 2025/2026
cardiomegaly with apical atrophy - diagnosis?
Ans: Chagas' disease
most common mets to bone
Ans: breast, lung, thyroid, testes, prostate, kidney
most common mets to brain
Ans: lung, breast, skin (melanoma), kidney (renal cell carcinoma), GI
most common mets to liver
Ans: colon, gastric, pancreatic, breast, lung carcinomas
Exampromax - Stuvia US
most common motor neuron disease
Approved By:
Ans: ALS
Charcot's triad of cholangitis
Ans: jaundice, RUQ pain, fever
Charcot-Leyden crystals - diagnosis?
- what are they?
Ans: bronchial asthma - eosinophil membranes
what is the defect in Chediak-Higashi disease?
Ans: phagocyte deficiency
S3 - possible diagnoses?
Ans: left-to-right shunt (VSD, PDA, ASD), mitral regurgitation, CHF (LV
failure)
what are Cheyne-Stokes respirations, and in what circumstance do they
occur?
, 4 Exampromax - Stuvia US 2025/2026
Ans: central apnea in CHF and increased intracranial pressure
Schiller-Duval bodies - diagnosis?
Ans: yolk sac tumor
what does chronic atrophic gastritis predispose to?
Ans: gastric carcinoma
what is Sezary syndrome?
Ans: cutaneous T-cell lymphoma
DES (diethylstilbesterol- prescribed to pregnant women in 60s) exposure in
utero predisposes to what?
Exampromax - Stuvia US
Ans: clear cell adenocarcinoma of the vagina
Approved By:
cold agglutinins - possible diagnoses?
Ans: Mycoplasma pneumonia or infectious mononucleosis
Schwartzman reaction - associated with?
Ans: Neisseria meningitidis
signet-ring cells - diagnosis?
Ans: gastric carcinoma
Councilman bodies - diagnosis?
Ans: toxic or viral hepatitis
Cowdry type A bodies - caused by what?
Ans: herpesvirus
hypochromic microcytosis - possible diagnoses?
Usmle Step 1 First Aid Questions with Detailed Verified
Answers (100% Correct Answers) /Already Graded A+
polyostotic fibrous dysplasia, precocious puberty, cafe-au-lait spots, short
stature, young girls - diagnosis?
Ans: Albright's syndrome
blue-domed cysts - diagnosis?
Ans: fibrocystic change of the breast
Wermer's syndrome - also known as?
Ans: MEN type I
Exampromax - Stuvia US
"wire loop" appearance on Light microscopy- diagnosis?
Approved By:
Ans: lupus nephropathy
what is the defect in Job's syndrome?
Ans: neutrophil chemotaxis abnormality - due to failure of IFN-gamma
production by helper T cells
xanthochromia of CSF - diagnosis?
Ans: subarachnoid hemorrhage
4 most common brain tumors in adults
Ans: mets > astrocytoma (including glioblastoma multiforme) >
meningioma > schwannoma
most common supratentorial brain tumor in kids
Ans: craniopharyngioma
most common bug in debilitated, hospitalized pneumonia patient
, 2 Exampromax - Stuvia US 2025/2026
Ans: Klebsiella
pseudopalisade tumor cell arrangement - diagnosis?
Ans: glioblastoma multiforme
pseudorosettes - diagnosis?
Ans: Tumour(Ewing's sarcoma)
nutmeg liver - diagnosis?
Ans: CHF
"Orphan Annie" nuclei - diagnosis?
Exampromax - Stuvia US
Ans: papillary carcinoma of the thyroid
Approved By:
painless jaundice - diagnosis?
Ans: pancreatic cancer (of head)
most common liver disease
Ans: alcoholic liver disease
"brown tumor" of bone - possible diagnoses?
- what causes the brown color?
Ans: hyperparathyroidism or osteitis fibrosa cystica (von Recklinghausen's
disease)
- color is due to hemorrhage in cysts
renal epithelial casts in urine - diagnosis?
Ans: acute toxic/viral nephrosis
most common location of brain tumors in kids
Ans: infratentorial
, 3 Exampromax - Stuvia US 2025/2026
cardiomegaly with apical atrophy - diagnosis?
Ans: Chagas' disease
most common mets to bone
Ans: breast, lung, thyroid, testes, prostate, kidney
most common mets to brain
Ans: lung, breast, skin (melanoma), kidney (renal cell carcinoma), GI
most common mets to liver
Ans: colon, gastric, pancreatic, breast, lung carcinomas
Exampromax - Stuvia US
most common motor neuron disease
Approved By:
Ans: ALS
Charcot's triad of cholangitis
Ans: jaundice, RUQ pain, fever
Charcot-Leyden crystals - diagnosis?
- what are they?
Ans: bronchial asthma - eosinophil membranes
what is the defect in Chediak-Higashi disease?
Ans: phagocyte deficiency
S3 - possible diagnoses?
Ans: left-to-right shunt (VSD, PDA, ASD), mitral regurgitation, CHF (LV
failure)
what are Cheyne-Stokes respirations, and in what circumstance do they
occur?
, 4 Exampromax - Stuvia US 2025/2026
Ans: central apnea in CHF and increased intracranial pressure
Schiller-Duval bodies - diagnosis?
Ans: yolk sac tumor
what does chronic atrophic gastritis predispose to?
Ans: gastric carcinoma
what is Sezary syndrome?
Ans: cutaneous T-cell lymphoma
DES (diethylstilbesterol- prescribed to pregnant women in 60s) exposure in
utero predisposes to what?
Exampromax - Stuvia US
Ans: clear cell adenocarcinoma of the vagina
Approved By:
cold agglutinins - possible diagnoses?
Ans: Mycoplasma pneumonia or infectious mononucleosis
Schwartzman reaction - associated with?
Ans: Neisseria meningitidis
signet-ring cells - diagnosis?
Ans: gastric carcinoma
Councilman bodies - diagnosis?
Ans: toxic or viral hepatitis
Cowdry type A bodies - caused by what?
Ans: herpesvirus
hypochromic microcytosis - possible diagnoses?
