PHY3181 (Male) Exam Study Guide 100% Pass
FSH stimulates the Sertoli cell to produce inhibin. - ANSWER True
Gonadotrophins are produced by the pars intermedius of the pituitary - ANSWER False
GnRH (LHRH) is produced by the - ANSWER Hypothalamus
Gonadotrophs are modified neurones. - ANSWER False
Pituitary synthesises FSH and LH and releases them directly into the blood stream. -
ANSWER True
Testosterone feeds back negatively on the pituitary and hypothalamus to reduce GnRH,
and LH secretion. - ANSWER True
Primary testicular failure increases or decreases circulating LH and FSH levels? -
ANSWER Increase
Spermiogenesis involves mitosis and meiosis? - ANSWER False
Duration of the spermatogenic wave is the same in rodents and humans. - ANSWER
False
Spermatids undergo a final meiotic division before sperm shaping. - ANSWER false
Tight junctions develop between Sertoli cells and germ cells. - ANSWER false
The sperm tail develops from the distal centriole - ANSWER true
Spermatogonia are the first germ cells to be affected by heat stress. - ANSWER false
Which part of the male reproductive tract provides the largest volume of fluid for the
ejaculate? - ANSWER seminal vesicles
Leydig cells produce - ANSWER testosterone
Sertoli cells synthesize testosterone - ANSWER false
Leydig cells synthesize ABP - ANSWER false
The enzyme aromatase converts androstenedione to oestradiol - ANSWER false
The enzyme 5alpha-reductase converts 5alphaDHT to oestradiol. - ANSWER false
_______ is the most influential androgen in the male tract. - ANSWER 5alphaDHT
Pulsetile release of LH causes pulsetile release of testosterone from Leydig cells -
ANSWER true
, The prostate has the same embryological origin as the vas deferens. - ANSWER false
Pregnenolone is the usual starting product in synthesis of testosterone. - ANSWER false
Aromatase converts androgen to oestrogen. - ANSWER true
Sertoli cells in the testicular interstitial compartment produce testosterone. - ANSWER
False
Spermiogenesis is the first stage of spermatogenesis, where the spermatogonia divide
via mitosis to produce spermatocytes - ANSWER False
______ is a steroidogenic enzyme responsible for the conversion of androgens to
estrogens - ANSWER armoatase
In the ________ of the testis, LH stimulates ______ cells which produce testosterone. -
ANSWER interstitium
leydig
_____ cells, located in the _______, respond to FSH and produce ____ as well as androgen
binding protein. - ANSWER sertoli
seminiferous tubules
inhibin
Leydig and Sertoli cells both express _____ and produce estrogen, although ____ cells
are the primary source of estrogen in the human testis. - ANSWER aromatase
Leydig
The _____ are also where sperm are produced, via the process of _____ . - ANSWER
seminiferous tubules
spermatogenesis
5α-reductase converts testosterone to the more potent androgen, __________, which
signals via the ______ - ANSWER DHT
androgen receptor (AR)
In contrast, aromatase converts testosterone into _________, which signals via the
_________ - ANSWER estradiol
estrogen receptor (ER)
Steroid abuse in males can lead to many adverse side-effects. Which of the below is
NOT a typical side-effect of steroid abuse in men?
Select one:
FSH stimulates the Sertoli cell to produce inhibin. - ANSWER True
Gonadotrophins are produced by the pars intermedius of the pituitary - ANSWER False
GnRH (LHRH) is produced by the - ANSWER Hypothalamus
Gonadotrophs are modified neurones. - ANSWER False
Pituitary synthesises FSH and LH and releases them directly into the blood stream. -
ANSWER True
Testosterone feeds back negatively on the pituitary and hypothalamus to reduce GnRH,
and LH secretion. - ANSWER True
Primary testicular failure increases or decreases circulating LH and FSH levels? -
ANSWER Increase
Spermiogenesis involves mitosis and meiosis? - ANSWER False
Duration of the spermatogenic wave is the same in rodents and humans. - ANSWER
False
Spermatids undergo a final meiotic division before sperm shaping. - ANSWER false
Tight junctions develop between Sertoli cells and germ cells. - ANSWER false
The sperm tail develops from the distal centriole - ANSWER true
Spermatogonia are the first germ cells to be affected by heat stress. - ANSWER false
Which part of the male reproductive tract provides the largest volume of fluid for the
ejaculate? - ANSWER seminal vesicles
Leydig cells produce - ANSWER testosterone
Sertoli cells synthesize testosterone - ANSWER false
Leydig cells synthesize ABP - ANSWER false
The enzyme aromatase converts androstenedione to oestradiol - ANSWER false
The enzyme 5alpha-reductase converts 5alphaDHT to oestradiol. - ANSWER false
_______ is the most influential androgen in the male tract. - ANSWER 5alphaDHT
Pulsetile release of LH causes pulsetile release of testosterone from Leydig cells -
ANSWER true
, The prostate has the same embryological origin as the vas deferens. - ANSWER false
Pregnenolone is the usual starting product in synthesis of testosterone. - ANSWER false
Aromatase converts androgen to oestrogen. - ANSWER true
Sertoli cells in the testicular interstitial compartment produce testosterone. - ANSWER
False
Spermiogenesis is the first stage of spermatogenesis, where the spermatogonia divide
via mitosis to produce spermatocytes - ANSWER False
______ is a steroidogenic enzyme responsible for the conversion of androgens to
estrogens - ANSWER armoatase
In the ________ of the testis, LH stimulates ______ cells which produce testosterone. -
ANSWER interstitium
leydig
_____ cells, located in the _______, respond to FSH and produce ____ as well as androgen
binding protein. - ANSWER sertoli
seminiferous tubules
inhibin
Leydig and Sertoli cells both express _____ and produce estrogen, although ____ cells
are the primary source of estrogen in the human testis. - ANSWER aromatase
Leydig
The _____ are also where sperm are produced, via the process of _____ . - ANSWER
seminiferous tubules
spermatogenesis
5α-reductase converts testosterone to the more potent androgen, __________, which
signals via the ______ - ANSWER DHT
androgen receptor (AR)
In contrast, aromatase converts testosterone into _________, which signals via the
_________ - ANSWER estradiol
estrogen receptor (ER)
Steroid abuse in males can lead to many adverse side-effects. Which of the below is
NOT a typical side-effect of steroid abuse in men?
Select one:
