Kuby Immunology Chapter 1-4 (2025) comprehensive questions and verified detailed solutions (
MULTIPLE CHOICES) |100% CORRECT!!
Which of the following generally does not apply to bone marrow (a primary lymphoid organ)
and secondary lymphoid organs?
A) cellular proliferation
B) differentiation of lymphocytes
C) cellular interaction
D) antigen-dependent response
E) None of the above. - correct answer D
Which of the following apply uniquely to secondary lymphoid organs?
A) presence of precursor B and T cells
B) circulation of lymphocytes
C) terminal differentiation
D) cellular proliferation
E) All of the above. - correct answer C
Which of the following does not apply to "innate" immune mechanisms?
A) absence of specificity
B) activation by a stimulus
C) involvement of multiple cell types
D) a memory component - correct answer D
Which of the following is the major function of the lymphoid system?
A) innate immunity
B) inflammation
C) phagocytosis
D) acquired immunity
,Kuby Immunology Chapter 1-4 (2025) comprehensive questions and verified detailed solutions (
MULTIPLE CHOICES) |100% CORRECT!!
E) None of the above. - correct answer D
Removal of the bursa of Fabricius from a chicken results in
A) a markedly decreased number of circulating T lymphocytes.
B) anemia.
C) delayed rejection of skin graft.
D) low serum levels of antibodies in serum.
E) all of the above.
F) none of the above. - correct answer D
The germinal centers found in the cortical region of lymph nodes and the peripheral region of
splenic periarteriolar lymphatic tissue
A) support the development of immature B and T cells.
B) function in the removal of damaged erythrocytes from the circulation.
C) act as the major source of stem cells and thus help to maintain hematopoiesis.
D) provide an infrastructure that on antigenic stimulation contains large populations of B
lymphocytes and plasma cells.
E) are the sites of NK-cell differentiation. - correct answer D
Which of the following is correct?
A) NK cells proliferate in response to antigen.
B) NK cells kill their target cells by phagocytosis and intracellular digestion.
C) NK cells are a subset of polymorphonuclear cells.
D) NK-cell killing is extracellular.
E) NK cells are particularly effective against certain bacteria. - correct answer D
A large glycoprotein has been enzymatically digested in the laboratory to yield a mixture of
glycopeptides ranging in size from 4 to 6 amino acids in length. Which of the following would be
expected if the peptide mixture were administered to an exerimental animal together with an
adjuvant such as complete Freund's adjuvant?
, Kuby Immunology Chapter 1-4 (2025) comprehensive questions and verified detailed solutions (
MULTIPLE CHOICES) |100% CORRECT!!
A) peptide-specific antibodies would be generated using the peptide mixture alone
B) carbohydrate-specific antibodies would be generated only if an adjuvant were administered
with the peptide mixture
C) peptide-specific antibodies would be generated only if they were injected with a separate
uncoupled protein carrier
D) peptide-specific and carbohydrate-specific antibody and T-cell responses would be
generated using the peptide mixture alone
E) there would be neither a humoral nor cell-mediated immune response to the peptides in the
mixture - correct answer E
The protection against smallpox virus infection afforded by prior infection with cowpox virus
represents
A) antigenic specificity
B) antigenic cross-reactivity
C) enhanced viral uptake by macrophages
D) innate immunity
E) passive protection - correct answer B
Converting a toxin to a toxoid
A) makes the toxin more immunogenic
B) reduces the pharmacological activity of the toxin
C) enhances binding with the antitoxin
D) induces only innate immunity
E) increases phagocytosis - correct answer B
Haptens
A) require carrier molecules to be immunogenic
B) react with specific antibodies when homologous carriers are not employed
C) interact with specific antibody even if the hapten is monovalent
MULTIPLE CHOICES) |100% CORRECT!!
Which of the following generally does not apply to bone marrow (a primary lymphoid organ)
and secondary lymphoid organs?
A) cellular proliferation
B) differentiation of lymphocytes
C) cellular interaction
D) antigen-dependent response
E) None of the above. - correct answer D
Which of the following apply uniquely to secondary lymphoid organs?
A) presence of precursor B and T cells
B) circulation of lymphocytes
C) terminal differentiation
D) cellular proliferation
E) All of the above. - correct answer C
Which of the following does not apply to "innate" immune mechanisms?
A) absence of specificity
B) activation by a stimulus
C) involvement of multiple cell types
D) a memory component - correct answer D
Which of the following is the major function of the lymphoid system?
A) innate immunity
B) inflammation
C) phagocytosis
D) acquired immunity
,Kuby Immunology Chapter 1-4 (2025) comprehensive questions and verified detailed solutions (
MULTIPLE CHOICES) |100% CORRECT!!
E) None of the above. - correct answer D
Removal of the bursa of Fabricius from a chicken results in
A) a markedly decreased number of circulating T lymphocytes.
B) anemia.
C) delayed rejection of skin graft.
D) low serum levels of antibodies in serum.
E) all of the above.
F) none of the above. - correct answer D
The germinal centers found in the cortical region of lymph nodes and the peripheral region of
splenic periarteriolar lymphatic tissue
A) support the development of immature B and T cells.
B) function in the removal of damaged erythrocytes from the circulation.
C) act as the major source of stem cells and thus help to maintain hematopoiesis.
D) provide an infrastructure that on antigenic stimulation contains large populations of B
lymphocytes and plasma cells.
E) are the sites of NK-cell differentiation. - correct answer D
Which of the following is correct?
A) NK cells proliferate in response to antigen.
B) NK cells kill their target cells by phagocytosis and intracellular digestion.
C) NK cells are a subset of polymorphonuclear cells.
D) NK-cell killing is extracellular.
E) NK cells are particularly effective against certain bacteria. - correct answer D
A large glycoprotein has been enzymatically digested in the laboratory to yield a mixture of
glycopeptides ranging in size from 4 to 6 amino acids in length. Which of the following would be
expected if the peptide mixture were administered to an exerimental animal together with an
adjuvant such as complete Freund's adjuvant?
, Kuby Immunology Chapter 1-4 (2025) comprehensive questions and verified detailed solutions (
MULTIPLE CHOICES) |100% CORRECT!!
A) peptide-specific antibodies would be generated using the peptide mixture alone
B) carbohydrate-specific antibodies would be generated only if an adjuvant were administered
with the peptide mixture
C) peptide-specific antibodies would be generated only if they were injected with a separate
uncoupled protein carrier
D) peptide-specific and carbohydrate-specific antibody and T-cell responses would be
generated using the peptide mixture alone
E) there would be neither a humoral nor cell-mediated immune response to the peptides in the
mixture - correct answer E
The protection against smallpox virus infection afforded by prior infection with cowpox virus
represents
A) antigenic specificity
B) antigenic cross-reactivity
C) enhanced viral uptake by macrophages
D) innate immunity
E) passive protection - correct answer B
Converting a toxin to a toxoid
A) makes the toxin more immunogenic
B) reduces the pharmacological activity of the toxin
C) enhances binding with the antitoxin
D) induces only innate immunity
E) increases phagocytosis - correct answer B
Haptens
A) require carrier molecules to be immunogenic
B) react with specific antibodies when homologous carriers are not employed
C) interact with specific antibody even if the hapten is monovalent
