PHARMACOLOGY PRACTICE QUESTIONS WITH CORRECT ANSWERS 2025

PHARMACOLOGY PRACTICE
QUESTIONS WITH CORRECT
ANSWERS 2025/2026
FollowingAtheAadministrationAofAsublingualAnitroglycerinAtoAaAclientAexperiencingAanAacuteAan
ginalAattack,AwhichAassessmentAfindingAindicatesAtoAtheAnurseAthatAtheAdesiredAeffectAhasAbee
nAachieved?



A)AClientAstatesAchestApainAisArelieved.

B)AClient'sApulseAdecreasesAfromA120AtoA90.A

C)AClient'sAsystolicAbloodApressureAdecreasesAfromA180AtoA90.

D)AClient'sASaO2AlevelAincreasesAfromA92%AtoA96%.A-
AcorrectAanswersClientAstatesAchestApainAisArelieved.A




Rationale:ANitroglycerinAreducesAmyocardialAoxygenAconsumptionAwhichAdecreasesAischemiaA
andAreducesAchestApainA(A).A(BAandAD)AwouldAalsoAoccurAifAtheAanginaAwasArelieved,AbutAareAno
tAasAsignificantAasAtheAclient'sAsubjectiveAreportAofAdecreasedApain.A(C)AmayAindicateAaAreducti
onAinApain,AorAaApotentiallyAseriousAsideAeffectAofAtheAmedication.

FollowingAheparinAtreatmentAforAaApulmonaryAembolism,AaAclientAisAbeingAdischargedAwithAaAp
rescriptionAforAwarfarinACoumadin.AInAconductingAdischargeAteaching,AtheAnurseAadvisesAtheAc
lientAtoAhaveAwhichAdiagnosticAtestAmonitoredAregularlyAafterAdischarge?A



A)APerfusionAscan.A

B)AProthrombinATimeA(PT/INR).A

C)AActivatedApartialAthromboplastinA(APTT).A

D)ASerumACoumadinAlevelA(SCL).A-AcorrectAanswersProthrombinATimeA(PT/INR)A



Rationale:AWhenAusedAforAaAclientAwithApulmonaryAembolus,AtheAtherapeuticAgoalAforAwarfari
nAtherapyAisAaAPTA1½AtoA2½AtimesAgreaterAthanAtheAcontrol,AorAanAINRAofA2AtoA3A(B).AAAperfusio
nAmightAbeAperformedAtoAmonitorAlungAfunction,AbutAnotAmonthlyA(A).AAPTTAisAmonitoredAforA
theAclientAreceivingAheparinAtherapyA(C).AAAbloodAlevelAforACoumadinAcannotAbeAmeasuredA(D)
.

,AAhealthcareAproviderAprescribesAcephalexinAmonohydrateAKeflexAforAaAclientAwithAaApostoper
ativeAinfection.AItAisAmostAimportantAforAtheAnurseAtoAassessAforAwhatAadditionalAdrugAallergyAb
eforeAadministeringAthisAprescription?



A)APenicillins.

B)AAminoglycosides.

C)AErythromycins.

D)ASulfonamides.A-AcorrectAanswersPenicillin



Rationale:ACross-
allergiesAexistAbetweenApenicillinsA(A)AandAcephalosporins,AsuchAasAcephalexinAmonohydrateA(
Keflex),AsoAcheckingAforApenicillinAallergyAisAaAwiseAprecautionAbeforeAadministeringAthisAdrug.

AAclientAisAadmittedAtoAtheAcoronaryAcareAunitAwithAaAmedicalAdiagnosisAofAacuteAmyocardialAi
nfarction.AWhichAmedicationAprescriptionAdecreasesAbothApreloadAandAafterload?A



A)ANitroglycerin.A

B)APropranololA(Inderal).A

C)AMorphine.A

D)ACaptoprilA(Capoten).A-AcorrectAanswersNitroglycerinA



Rationale:ANitroglycerinA(A)AisAaAnitrateAthatAcausesAperipheralAvasodilationAandAdecreasesAco
ntractility,AtherebyAdecreasingAbothApreloadAandAafterload.A(B)AisAaAbetaAadrenergicAblockerAth
atAdecreasesAbothAheartArateAandAcontractility,AbutAonlyAdecreasesAafterload.AMorphineA(C)Ade
creasesAmyocardialAoxygenAconsumptionAandApreload.ACapotenA(D)AisAanAangiotensinAconverti
ngAenzymeA(ACE)AinhibitorAthatAactsAtoApreventsAvasoconstriction,AtherebyAdecreasingAbloodA
pressureAandAafterload.

WhichAdosingAscheduleAshouldAtheAnurseAteachAtheAclientAtoAobserveAforAaAcontrolled-
releaseAoxycodoneAprescription?A



A)AAsAneeded.

B)AEveryA12Ahours.A

,C)AEveryA24Ahours.A

D)AEveryA4AtoA6Ahours.A-AcorrectAanswersEveryA12AhoursA



Rationale:AAAcontrolled-releaseAoxycodoneAprovidesAlong-
actingAanalgesiaAtoArelieveAmoderateAtoAsevereApain,AsoAaAdosingAscheduleAofAeveryA12AhoursA(
B)AprovidesAtheAbestAaround-the-clockApainAmanagement.AControlled-
releaseAoxycodoneAisAnotAprescribedAforAbreakthroughApainAonAaAPRNAorAasAneededAscheduleA
(A).A(C)AisAinadequateAforAcontinuousApainAmanagement.AUsingAaAscheduleAofAeveryA4AtoA6Ahou
rsA(D)AmayAjeopardizeApatientAsafetyAdueAtoAcumulativeAeffects.

AApeakAandAtroughAlevelAmustAbeAdrawnAforAaAclientAreceivingAantibioticAtherapy.AWhatAisAtheA
optimumAtimeAforAtheAnurseAtoAobtainAtheAtroughAlevel?A



A)ASixtyAminutesAafterAtheAantibioticAdoseAisAadministered.AB)AImmediatelyAbeforeAtheAnextAan
tibioticAdoseAisAgiven.A

C)AWhenAtheAnextAbloodAglucoseAlevelAisAtoAbeAchecked.A

D)AThirtyAminutesAbeforeAtheAnextAantibioticAdoseAisAgiven.A-
AcorrectAanswersImmediatelyAbeforeAtheAnextAantibioticAdoseAisAgivenA




Rationale:ATroughAlevelsAareAdrawnAwhenAtheAbloodAlevelAisAatAitsAlowest,AwhichAisAtypicallyAju
stAbeforeAtheAnextAdoseAisAgivenA(B).A(A,AC,AandAD)AdoAnotAdescribeAtheAoptimumAtimeAforAobta
iningAaAtroughAlevelAofAanAantibiotic.

AfterAabdominalAsurgery,AaAmaleAclientAisAprescribedAlowAmolecularAweightAheparinALMWH.AD
uringAadministrationAofAtheAmedication,AtheAclientAasksAtheAnurseAwhyAheAisAreceivingAthisAme
dication.AWhichAisAtheAbestAresponseAforAtheAnurseAtoAprovide?A



A)AThisAmedicationAisAaAbloodAthinnerAgivenAtoApreventAbloodAclotAformation.A

B)AThisAmedicationAenhancesAantibioticsAtoApreventAinfection.A

C)AThisAmedicationAdissolvesAanyAclotsAthatAdevelopAinAtheAlegs.A

D)AThisAabdominalAinjectionAassistsAinAtheAhealingAofAtheAabdominalAwound.A-
AcorrectAanswersThisAmedicationAisAaAbloodAthinnerAgivenAtoApreventAbloodAclotAformationA

, Rationale:AUnfractionatedAheparinAorAlowAmolecularAweightAheparinA(LMWH)AisAanAanticoagul
antAthatAinhibitsAthrombin-
mediatedAconversionAofAfibrinogenAtoAfibrinAandAisAgivenAprophylacticallyAtoApreventApostoper
ativeAvenousAthrombosisA(A)AorAtoAtreatApulmonaryAembolismAorAdeepAveinAthrombosisAfollow
ingAkneeAandAabdominalAsurgeries.AHeparinAdoesAnotAdissolveAclotsAbutApreventsAclotAextensi
onAorAfurtherAclotAformationA(C).ATheAanticoagulantAheparinAdoesAnotApreventAinfectionA(B)AorA
influenceAoperativeAwoundAhealingA(D).

AAclientAwithAParkinson'sAdiseaseAisAtakingAcarbidopa-
levodopaA(Sinemet).AWhichAobservationAbyAtheAnurseAshouldAindicateAthatAtheAdesiredAoutco
meAofAtheAmedicationAisAbeingAachieved?A



A)ADecreasedAbloodApressure.A

B)ALesseningAofAtremors.A

C)AIncreasedAsalivation.A

D)AIncreasedAattentionAspan.A-AcorrectAanswersLesseningAofAtremorsA



Rationale:ASinemetAincreasesAtheAamountAofAlevodopaAtoAtheACNSA(dopamineAtoAtheAbrain).AIn
creasedAamountsAofAdopamineAimproveAtheAsymptomsAofAParkinson's,AsuchAasAinvoluntaryAm
ovements,ArestingAtremorsA(B),AshufflingAgait,Aetc.A(A)AisAaAsideAeffectAofASinemet.ADecreasedAd
roolingAwouldAbeAaAdesiredAeffect,AnotA(C).ASinemetAdoesAnotAaffectA(D).

AAclientAisAreceivingAmetoprololALopressorASR.AWhatAassessmentAisAmostAimportantAforAtheAnu
rseAtoAobtain?A

A)ATemperature.A

B)ALungAsounds.A

C)ABloodApressure.A

D)AUrinaryAoutput.A-AcorrectAanswersBloodApressureA



Rationale:AItAisAmostAimportantAtoAmonitorAtheAbloodApressureA(C)AofAclientsAtakingAthisAmedic
ationAbecauseALopressorAisAanAantianginal,Aantiarrhythmic,AantihypertensiveAagent.AWhileA(AA
andAB)AareAimportantAdataAtoAobtainAonAanyAclient,AtheyAareAnotAasAimportantAforAaAclientArece
ivingALopressorAasA(C).AIntakeAandAoutputAratiosAandAdailyAweightsAshouldAbeAmonitoredAwhile
AtakingALopressorAtoAassessAforAsignsAandAsymptomsAofAcongestiveAheartAfailure,AbutA(D)AaloneA


doesAnotAhaveAtheAimportanceAofA(C).