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NURS 5315 Test 5 (Module 10) 2024/2025 Exam Questions and Answers | A+ Score Assured

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NURS 5315 Test 5 (Module 10) 2024/2025 Exam Questions and Answers | A+ Score Assured Nephron structure -

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NURS 5315 Test 5 (Module 10) 2024/2025
Exam Questions and Answers | A+
Score Assured



Nephron structure - 🧠 ANSWER ✔✔- Glomerulus- collection of capillaries

and is responsible for filtering blood, reabsorbs amino acids, bicarb,

sodium, chloride, phosphate, potassium, water

- Proximal tubule- can excrete phosphate, site of action for angiotensin II

which stimulates sodium, water and bicarb reabsorption.

- Descending loop of Henle- passively reabsorbs water, concentrates urine.

- Ascending loop of Henle- actively reabsorbs sodium, potassium, chloride,

induces reabsorption of magnesium and calcium, impermeable to water,

therefore, makes water more dilute.

Distal convoluted tubule- actively reabsorbs sodium, permeable to water,

causes urine to be more dilute. Site of action for ADH hormone and

aldosterone




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,Renal blood vessels - 🧠 ANSWER ✔✔Autoregulation- autoregulation

affects amount of blood flow to kidneys and also rate of filtration. Decrease

in arterial blood pressure and decrease in arterial blood volume causes a

decrease in renal perfusion. Decreased perfusion causes reduced GFR,

and decrease in fluid and sodium in distal tubule. This decrease is senses

by JGA which sends signals to relax blood vessels in order to help bring

blood to glomeruli, JGA releases renin which converts angiotenison to

angio I, this passes through lungs and stimulates release of angiotensin

converting enzyme. ACE converts angio I to angio II, which stimulates

vasoconstriction to help increase glomerular back pressure and increase

GFR. Angio II also responsible for stimulating release of aldosterone. This

results in additional reabsorption of water, increased BP and increased GF

rate.


aging effect on kidneys - 🧠 ANSWER ✔✔Reach adult size by adolescence


Hypertrophy with older age, reduced ability to excrete urine, kyperkalemia

from reduced excretion, more glucose excreted because of decreased

reabsorption (not necessarily indicator of diabetes), drugs not clearing as

easily, harder to activate vitamin d, which affects calcium absorption.




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, GFR- increased directly after birth, reaches adult levels by age 2, more

dilute urine up to 6mo of age, renal blood flow and GFR decrease with

older age (d/t atherosclerosis)




Nephron- decrease in number and size with age (atherosclerosis), number

of nephrons at age 75 decreased by 30%.




Tubular system- immature in infants (harder to excrete potassium, reabsorb

bicarb, buffer hydrogen), matures by age 2. Tubular atrophy is common

with age.




Bladder- descends into pelvis after birth, may not void for 12-24 hours

following birth. Frequency and nocturia are common with age.


Renal injury - 🧠 ANSWER ✔✔Focal- localized, <50% of glomeruli affected




Diffuse- >50% of glomeruli affected *most common*




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STATEMENT. ALL RIGHTS RESERVED

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