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N5315 Advanced Pathophysiology Renal 2024/2025 Exam Questions Marking Scheme New Update | A+ Rated $12.49
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N5315 Advanced Pathophysiology Renal 2024/2025 Exam Questions Marking Scheme New Update | A+ Rated

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  • Course
  • Advanced pathophysiology
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  • Advanced Pathophysiology

N5315 Advanced Pathophysiology Renal 2024/2025 Exam Questions Marking Scheme New Update | A+ Rated Calcitriol -

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  • March 24, 2025
  • 25
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Advanced pathophysiology
  • Advanced pathophysiology
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NinjaNerd
N5315 Advanced Pathophysiology Renal
2024/2025 Exam Questions Marking
Scheme New Update | A+ Rated



Calcitriol - 🧠 ANSWER ✔✔active form of vitamin D which is converted in

the kidneys

-helps with the absorption of calcium

-decreases renal calcium excretion


podocytes - 🧠 ANSWER ✔✔epithelial cells in the bowman capsule which

wrap around the capillaries of the glomeruli. They form long processes (foot

projections) called pedicels which wrap around the glomerular capillaries

and leave slits between them. Blood is filtered through these slits


JGA (juxtaglomerular apparatus) - 🧠 ANSWER ✔✔collection of cells

consisting of the juxtaglomerular cells, the macula densa, and the

mesangial cells


mesangial cells - 🧠 ANSWER ✔✔function as macrophages




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,-cells the monitor renal pressure and help maintain normal GFR through

the release of renin


release of renin - 🧠 ANSWER ✔✔helps increase GFR by releasing

angiotensin II which constricts the efferent arteriole thereby increasing

pressure to the glomerulus


macula densa cells - 🧠 ANSWER ✔✔group of epithelial cells located in the

distal convoluted tubule that are in close contact with afferent and efferent

arterioles. They help to regulate GFR


Renal blood flow - 🧠 ANSWER ✔✔-1000-1200mL/min of blood


-20% is filtered out and of the capillaries and enters the Bowman's capsule

-filtrate then enters proximal tubule at 125mL/min = GFR

-80% flows out of glomerular space and into efferent arterioles

-efferent arterioles divide into capillaries that surround the tubules =

peritubular capillaries

-network of capillaries in conjunction with epithelial cells of the tubules is

responsible for solute exchange and water regulation




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, ACE inhibitors - 🧠 ANSWER ✔✔blocks the action of angiotensin II on the

efferent arterioles and therefore have a renal protective quality in diabetics

because it decreases the pressure within the glomeruli; however, this mode

of action may also result in an acute kidney injury, particularly in someone

with renal artery stenosis


Calcium stones - 🧠 ANSWER ✔✔-most common stone


-frequently calcium oxalate or calcium phosphate

-caused by hyperparathyroidism=increased osteoclast activity which break

down bone


renal calculi - 🧠 ANSWER ✔✔-AKA nephrolithiasis


-AKA kidney stones

-made up of calcium, struvite, uric acid or cystine (an amino acid found in

most proteins)


Struvite stones - 🧠 ANSWER ✔✔-second most common


-most troubling ones because they frequently cause complications with

intractable urinary tract infections, pain, bleeding, and abscess

-made of magnesium, ammonium, and phosphate salts



COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
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STATEMENT. ALL RIGHTS RESERVED

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