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PHAR 100 Questions and Correct
Answers/ Latest Update / Already
Graded
What 3 civilizations were mentioned in the module about the history
of drugs and what drug was associated with them?
Ans: Ancient Greece (opium and codeine), Ancient China (ma Huang),
and Ancient Egypt (purgatives)
What poisons were mentioned in the module?
Ans: Curare and Ergot
What is peyote?
Ans: Peyote is a small, spineless cactus, and has a mescaline which
causes halluciantions
Who invented complexes of arsenic and organic molecules which
later led to the cure for Syplihlis in 1900s
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Ans: Paul Ehrlich
who introduced sulfa drugs in 1930s
Ans: Gerhard Domagk
Who created penicillin in 1940s
Ans: Alexander Fleming
Who created streptomycin in 1950s
Ans: Selman Waksman
What are the 5 steps of drug development
Ans: Basic research, Preclinical trials, Clinical trials, Health Canada review
and manufacturing, and post market surveillance and phase IV clinical
trial
What 2 parts are in basic research and drug discovery
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Ans: Identification of target, and studying the target
What are the 2 types of preclinical trials
Ans: Toxicology studies, and pharmacology studies
What 3 things are a part of clinical trials?
Ans: Proof of safety, Methodology, and investigation
What are the 3 pahses of clinical trials
Ans: Phase 1 - lookds at ADME in small group
Phase 2 - looks at patients to see effects in medium sized group
Phase 3 - RCT with 1000's of people
What is a gold standard drug?
Ans: A drug which is the current treatment for a condition
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Why is it safe to take a drug which was just rebranded?
Ans: The rebrand drug and original must be bioequivalent which
basically means the same. The only thing that changes is the name.
Why are post-market surveillance and phase IV clinical trials so
important
Ans: Helps identify and new side effects specific to certain people.
What are drug targets?
Ans: Usually receptors and drug goes towards this thing to produce an
effect as either an agonist or antagonist
What is an agonist?
Ans: It is a drug that is capable of binding to, and activating, a receptor
What is an antagonist?
PHAR 100 Questions and Correct
Answers/ Latest Update / Already
Graded
What 3 civilizations were mentioned in the module about the history
of drugs and what drug was associated with them?
Ans: Ancient Greece (opium and codeine), Ancient China (ma Huang),
and Ancient Egypt (purgatives)
What poisons were mentioned in the module?
Ans: Curare and Ergot
What is peyote?
Ans: Peyote is a small, spineless cactus, and has a mescaline which
causes halluciantions
Who invented complexes of arsenic and organic molecules which
later led to the cure for Syplihlis in 1900s
,2 | Page
Ans: Paul Ehrlich
who introduced sulfa drugs in 1930s
Ans: Gerhard Domagk
Who created penicillin in 1940s
Ans: Alexander Fleming
Who created streptomycin in 1950s
Ans: Selman Waksman
What are the 5 steps of drug development
Ans: Basic research, Preclinical trials, Clinical trials, Health Canada review
and manufacturing, and post market surveillance and phase IV clinical
trial
What 2 parts are in basic research and drug discovery
,3 | Page
Ans: Identification of target, and studying the target
What are the 2 types of preclinical trials
Ans: Toxicology studies, and pharmacology studies
What 3 things are a part of clinical trials?
Ans: Proof of safety, Methodology, and investigation
What are the 3 pahses of clinical trials
Ans: Phase 1 - lookds at ADME in small group
Phase 2 - looks at patients to see effects in medium sized group
Phase 3 - RCT with 1000's of people
What is a gold standard drug?
Ans: A drug which is the current treatment for a condition
, 4 | Page
Why is it safe to take a drug which was just rebranded?
Ans: The rebrand drug and original must be bioequivalent which
basically means the same. The only thing that changes is the name.
Why are post-market surveillance and phase IV clinical trials so
important
Ans: Helps identify and new side effects specific to certain people.
What are drug targets?
Ans: Usually receptors and drug goes towards this thing to produce an
effect as either an agonist or antagonist
What is an agonist?
Ans: It is a drug that is capable of binding to, and activating, a receptor
What is an antagonist?
