PHAR 100 - Midterm Questions and Correct Answers/ Latest Update / Already Graded

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PHAR 100 - Midterm Questions and
Correct Answers/ Latest Update /
Already Graded
Key historical influences to pharmacology


Ans: -Civilizations: Greece, Egypt, China


-Poison: Curare, Ergot


-Religion




Why was zinc oxide an important compound


Ans: currently found in topical creams (i.e. calamine)




What did ancient greece, egypt, and china contribute


Ans: greece - opium - codeine + morphine


egypt - senna, purgatives


china - ephedrine (asthma)

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What is Curare's function as a poison + pharmaceutical


Ans: poison = paralysis/death, drug = anesthesia




What is Ergot's function as a poison + pharmaceutical


Ans: poison = mental frenzy, burning limbs, uterus contraction


pharm = ergotamine: treats migraines, ergonovine: arrests uterine

bleeding after childbirth




What did Paul Ehrlich design


Ans: organoarsenicals - binds to parasites = cure for syphillis




Name 9 basic drug development steps

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Ans: 1- drug discovery


2- pre-clinical


3- clinical trial: initial steps


4- phase 1: young healthy people


5- phase 2: people affected by disesase (~500 ppl)


6- phase 3: people affected by disease (1000+)


7- Health Canda review


8- Manufacturing


9 - Phase 4: tests over long period/taken concurrently w/ other drugs




Name 6 advertising techniques

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Ans: -before/after


-fear


-offer an easy solution


-attention catching


-celeb endorsement


-discredit other manufacturers




Name 3 drug targets


Ans: -receptors


-chemical rxn


-physical/chemical forces




Explain ED50


Ans: The dose that gives 50% of max. response