Psychiatry Shelf Exam Flashcards
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Bipolar symptoms in an older patient occurring for first time?
Ans: Right frontal hemisphere stroke
What drugs may cause lithium toxicity?
Ans: NSAIDs
Coarse tremor, ataxia, confusion, slurred speech, t-wave
flattening/inversion + U waves
Ans: Lithium toxicity
Mxn of lithium
Ans: Suppresses inositol triphosphate
Malformed tricuspid valve atrializes RV
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Ans: Ebstein's anomaly (Lithium toxicity)
Preferred treatment of bipolar in pregnant pt?
Ans: Clonazepam
Bipolar disorder with elevated LFTs and hepatitis
Ans: Valproate use
Bipolar disorder with SJS?
Ans: Lamotrigine
Bipolar disorder with agranulocytosis?
Ans: Carbamazepine
Shortened REM latency, more frequent REM
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Ans: Depression
Medications w/ side effect of with depression
Ans: IFN, BB, alpha-methyldopa, L-dopa, OCPs, EtOH, cocaine/amp
withdrawal, opiates
Medical diseases that may present w/ depression
Ans: HIV, Lyme disease, MS, hypothyroidism, acute intermittent porphyria,
uremia, Cushing's, Huntington's, MCA stroke
Leaden paralysis
Ans: Atypical depression
SSRI with most drug-drug interactions
Ans: Paroxetine
SSRIs most likely to have discontinuation syndrome
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Ans: Sertraline and fluvoxamine
Widened QRS complexes and prolonged QT interval
Ans: TCA overdose
Treatment for TCA overdose
Ans: Activated charcoal and IV sodium bicarb
Low potency anti-psychotics
Ans: Chlorpromazine and thioridazine
High potency anti-psychotics
Ans: Haloperidol and fluphenazine
Purple, grey metallic rash over sun-exposed areas and jaundice