NBMEl 29l Testl V1l (Latestl 2025/l 2026l
Update)l Questionsl &l Answers|l Gradel A|l
100%l Correctl (Verifiedl Solution)
Q:l Whatl canl causel atrophicl vaginitisl inl breastfeedingl women?
Answer:
l Lowl Estrogenl levelsl (Prolactinl increasel =>l GnRHl inhibition)
Q:l Aspirinl inhibitsl thel conversionl ofl whatl moleculel vial COXl 1l andl COXl 2l
inhibition
Answer:
l Arachidonatel (arachidonicl acid)l =>l Cyclicl Endoperoxidases
Q:l Substancel foundl inl pufferfishl thatl bindsl fastl voltage-gatedl sodiuml channelsl inl
nervel tissuel preventingl depolarization
Answer:
l Tetrodotoxin
Q:l Tamoxifenl MOA
Answer:
l Competitivel inhibitionl ofl estrogenl receptorl (SERM)
Q:l Whatl formsl thel crystalsl inl gout?
Answer:
l Sodiuml Monouratel (AKA:l monosodiuml urate)
,Q:l Increasedl levelsl ofl whatl stubtancel thatl isl commonl inl statesl ofl starvationl andl
untreatedl T1DMl whichl triggersl ketogenesisl andl formationl ofl ketonel bodies.
Answer:
l Increasedl Acetyll CoA
Q:l Whichl ofl thel followingl domainsl isl exchangedl froml IgMl forl anotherl Igl subclassl
inl isotypel switching?
Answer:
l Constantl Region:l 2,3,l andl 4
Q:l Whatl regionl ofl thel kidneyl isl mostl susceptiblel tol anoxicl injuryl (100%l nitrogenl
ventilation)
Answer:
,l Proximall Tubulel (highestl metabolicl demand)
Q:l Homovanillicl Acidl thel productl ofl thel degradationl ofl whatl sybstance(s)
Answer:
l Dopamine,l NE,l EPI
Q:l Deficiencyl ofl whatl enzymel essentiall forl catecholaminel synthesisl resultsl inl
progressivel dystonial andl possiblel cognitivel impairment?
Answer:
l Tyrosinel Hydroxylase
Q:l Cholinergicl receptorsl thatl arel locatedl postsynapticallyl inl thel effectorl organsl suchl
asl smoothl muscle,l cardiacl muscle,l andl glandsl suppliedl byl parasympatheticl fibers.
Answer:
l Muscarinicl Receptors
Q:l Onl alll ANSl postganglionicl neurons,l inl thel adrenall medulla,l andl atl neuromuscularl
junctionsl ofl skeletall muscle
Excitatoryl whenl AChl bindingl occurs
Answer:
l Nicotinel Receptors
Q:l Highlyl polarl moleculel withl manyl negativel chargesl thatl thereforel hasl highl affinityl
forl waterl andl functionsl asl al shockl absorberl atl thel molecularl inl thel artilagel
surroundingl thel knee.
Answer:
l Chondroitinl sulfate
Q:l MOAl forl treatmentl ofl influenzal infection?
, Answer:
l Neuraminidasel inhibitors:l preventl relesel ofl virusl forml infectedl cells
Q:l Whatl moleculel isl responsiblel forl thel heart'sl abilityl tol restorel lowl basall calciuml
concentrationsl duringl diastole
Answer:
l Sodium-Calciuml Exchanger
Q:l Whatl arel thel findingsl ofl ferritin,l iron,l andl totall ironl bindingl capacityl inl al patientl
withl anemial duel tol SLE?
Answer:
l Highl Ferritin
Lowl Iron
Lowl Totall iron-bindingl capacity
Q:l Whatl protienl buildsl upl inl parkinsonl disease?
Answer:
l Alpha-synuclein
Q:l Treatmentl withl CPAPl forl OSAl isl mostl usefull inl addressingl whatl majorl
complication?
Answer:
l Loweringl Bloodl Pressure
Q:l Craniall Nervel IXl (afferentl limbl ofl gagl reflex)
Answer:
l Glossopharyngeal
Q:l Craniall Nervel Xl (efferentl limbl ofl gagl reflex)
Update)l Questionsl &l Answers|l Gradel A|l
100%l Correctl (Verifiedl Solution)
Q:l Whatl canl causel atrophicl vaginitisl inl breastfeedingl women?
Answer:
l Lowl Estrogenl levelsl (Prolactinl increasel =>l GnRHl inhibition)
Q:l Aspirinl inhibitsl thel conversionl ofl whatl moleculel vial COXl 1l andl COXl 2l
inhibition
Answer:
l Arachidonatel (arachidonicl acid)l =>l Cyclicl Endoperoxidases
Q:l Substancel foundl inl pufferfishl thatl bindsl fastl voltage-gatedl sodiuml channelsl inl
nervel tissuel preventingl depolarization
Answer:
l Tetrodotoxin
Q:l Tamoxifenl MOA
Answer:
l Competitivel inhibitionl ofl estrogenl receptorl (SERM)
Q:l Whatl formsl thel crystalsl inl gout?
Answer:
l Sodiuml Monouratel (AKA:l monosodiuml urate)
,Q:l Increasedl levelsl ofl whatl stubtancel thatl isl commonl inl statesl ofl starvationl andl
untreatedl T1DMl whichl triggersl ketogenesisl andl formationl ofl ketonel bodies.
Answer:
l Increasedl Acetyll CoA
Q:l Whichl ofl thel followingl domainsl isl exchangedl froml IgMl forl anotherl Igl subclassl
inl isotypel switching?
Answer:
l Constantl Region:l 2,3,l andl 4
Q:l Whatl regionl ofl thel kidneyl isl mostl susceptiblel tol anoxicl injuryl (100%l nitrogenl
ventilation)
Answer:
,l Proximall Tubulel (highestl metabolicl demand)
Q:l Homovanillicl Acidl thel productl ofl thel degradationl ofl whatl sybstance(s)
Answer:
l Dopamine,l NE,l EPI
Q:l Deficiencyl ofl whatl enzymel essentiall forl catecholaminel synthesisl resultsl inl
progressivel dystonial andl possiblel cognitivel impairment?
Answer:
l Tyrosinel Hydroxylase
Q:l Cholinergicl receptorsl thatl arel locatedl postsynapticallyl inl thel effectorl organsl suchl
asl smoothl muscle,l cardiacl muscle,l andl glandsl suppliedl byl parasympatheticl fibers.
Answer:
l Muscarinicl Receptors
Q:l Onl alll ANSl postganglionicl neurons,l inl thel adrenall medulla,l andl atl neuromuscularl
junctionsl ofl skeletall muscle
Excitatoryl whenl AChl bindingl occurs
Answer:
l Nicotinel Receptors
Q:l Highlyl polarl moleculel withl manyl negativel chargesl thatl thereforel hasl highl affinityl
forl waterl andl functionsl asl al shockl absorberl atl thel molecularl inl thel artilagel
surroundingl thel knee.
Answer:
l Chondroitinl sulfate
Q:l MOAl forl treatmentl ofl influenzal infection?
, Answer:
l Neuraminidasel inhibitors:l preventl relesel ofl virusl forml infectedl cells
Q:l Whatl moleculel isl responsiblel forl thel heart'sl abilityl tol restorel lowl basall calciuml
concentrationsl duringl diastole
Answer:
l Sodium-Calciuml Exchanger
Q:l Whatl arel thel findingsl ofl ferritin,l iron,l andl totall ironl bindingl capacityl inl al patientl
withl anemial duel tol SLE?
Answer:
l Highl Ferritin
Lowl Iron
Lowl Totall iron-bindingl capacity
Q:l Whatl protienl buildsl upl inl parkinsonl disease?
Answer:
l Alpha-synuclein
Q:l Treatmentl withl CPAPl forl OSAl isl mostl usefull inl addressingl whatl majorl
complication?
Answer:
l Loweringl Bloodl Pressure
Q:l Craniall Nervel IXl (afferentl limbl ofl gagl reflex)
Answer:
l Glossopharyngeal
Q:l Craniall Nervel Xl (efferentl limbl ofl gagl reflex)
