Genetic Analysis-An Integrated Approach, 3rd Edition by
Mark f Sanders.
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,Genetics:`An`Integrated`Approach`(Sanders)
Chapter`1` ` The`Molecular`Basis`of`Heredity,`Variation,`and`Evolution
1.1` ` Multiple-Choice`Questions
1) Bacteria`are`single-celled`organisms`with`a`single`chromosome`found`in`which`cell`space?
A) nucleus
B) nucleolus
C) nucleoid
D) nuclear`envelope
E) mitochondria
Answer:` C`Sectio
n:` 1.1
Skill:` Knowledge/Comprehension
2) Sexual`reproduction`uses` to`generate` gametes,`which`join`at`fertilization.
A) meiosis;`haploid
B) mitosis;`haploid
C) meiosis;`diploid
D) mitosis;`diploid
E) mitosis;`identical
Answer:` A`Sectio
n:` 1.1
Skill:` Knowledge/Comprehension
3) When`a`diploid`cell`divides`by`mitosis,`the`result`is` .
A) identical`haploid`cells
B) identical`diploid`cells
C) unique`diploid`cells
D) unique`haploid`cells
E) a`zygote.
Answer:` B`Sectio
n:` 1.1
Skill:` Knowledge/Comprehension
4) Modern`genetics`consists`of`three`major`branches.`Which`of`these`branches,`also`known`as`―t
ransmission`genetics,‖`involves`the`study`of`the`transmission`of`traits`and`characteristics`in`su
ccessive`generations?
A) evolutionary
B) Mendelian
C) molecular
D) population
E) reproductive
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, Answer:` B`Sectio
n:` 1.1
Skill:` Knowledge/Comprehension
5) You`identify`a`new`unicellular`organism`with`multiple`chromosomes`organized`by`proteins`within`t
he`cell’s`nucleus.`Into`which`of`the`three`domains`of`life`might`this`organism`fit?
A) Archaea
B) Bacteria
C) Eukarya
D) Archaea`or`Bacteria
E) Archaea`or`Eukarya
Answer:` C`Sectio
n:` 1.1
Skill:` Application/Analysis
6) Watson`and`Crick`used`evidence`from`several`studies`to`determine`the`structure`of`DNA.`What`c
onclusion`were`they`able`to`draw`from`Rosalind`Franklin’s`X-ray`diffraction`data,`specifically?
A) DNA`consists`of`four`types`of`nucleotide`bases:`A,`T,`C,`and`G.
B) DNA`nucleotides`form`complementary`base`pairs.
C) Adenine`pairs`with`thymine`and`cytosine`pairs`with`guanine`when`they`are`on`opposite`DNA`
strands.
D) DNA`is`a`duplex,`with`two`strands`forming`a`double`helix.
E) The`DNA`strands`are`antiparallel,`and`the`strands`are`held`together`by`hydrogen`bonds.
Answer:` D`Sectio
n:` 1.2
Skill:` Knowledge/Comprehension
7) What`kind`of`bond`is`formed`between`the`5′`phosphate`group`of`one`nucleotide`and`the`3′`hydroxyl`(
OH)`group`of`the`adjacent`nucleotide?
A) ionic`bond
B) phosphodiester`bond
C) hydrogen`bond
D) disulfide`bond
E) hydroxyl`bond
Answer:` B`Sectio
n:` 1.2
Skill:` Knowledge/Comprehension
8) What`kind`of`bond`is`formed`between`complementary`base`pairs`to`join`the`two`DNA`strands`into`a`
double`helix?
A) ionic`bond
B) phosphodiester`bond
C) hydrogen`bond
D) disulfide`bond
E) peptide`bond
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, Answer:` C`Sectio
n:` 1.2
Skill:` Knowledge/Comprehension
9) Which`type(s)`of`RNA`is/are`translated`into`proteins?
A) mRNA
B) rRNA
C) tRNA
D) mRNA`and`rRNA
E) mRNA,`rRNA,`and`tRNA
Answer:` A`Sectio
n:` 1.3
Skill:` Knowledge/Comprehension
10) Which`enzyme`is`active`in`DNA`replication?
A) DNA`polymerase
B) RNA`polymerase
C) reverse`transcriptase
D) aminoacyl-tRNA`synthetase
E) RNase
Answer:` A`Sectio
n:` 1.2
Skill:` Knowledge/Comprehension
11) The`promoter`is`bound`by`which`enzyme?
A) DNA`polymerase
B) RNA`polymerase
C) Reverse`transcriptase
D) DNase
E) RNase
Answer:` B`Sectio
n:` 1.3
Skill:` Knowledge/Comprehension
12) What`is`the`process`of`synthesizing`proteins`from`mRNA`sequences?
A) replication
B) transcription
C) translation
D) transformation
E) transduction
Answer:` C`Sectio
n:` 1.3
Skill:` Knowledge/Comprehension
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