UNDERSTANDING PATHOPHYSIOLOGY p p
6th EDITION HUETHER
p
p p
CHAPTER 1-42 TEST BANK p p p
Chapterp01:pCellularpBiology
Huetherp&pMcCance:pUnderstandingpPathophysiology,p6thpEdition
MULTIPLEpCHOICE
1. Apstudentpispobservingpapcellpunderpthepmicroscope.pItpispobservedptophavepsuperco
iledpDNAwithphistones.pWhichpofpthepfollowingpwouldpalsopbepobservedpbypthepstu
dent?
a. Apsinglepcircularpchromosome
b. Apnucleus
c. Free-floatingpnuclearpmaterial
d. Noporganelles
ANS:p B
Thepcellpdescribedpispapeukaryoticpcell,psopitphasphistonespandpapsupercoiledpDNAp
withinpitsnucleus;pthus,pthepnucleuspshouldpbepobserved.pApsinglepcircularpchrom
osomepcalledpapprokaryotepcontainspfree-
floatingpnuclearpmaterialpbutphaspnoporganelles.
REF:p p.p2
2. Apnursepispinstructingpthepstaffpaboutpcellularpfunctions.pWhichpcellularpfunctionpisp
thepnursepdescribingpwhenpanpisolatedpcellpabsorbspoxygenpandpusespitptoptransformp
nutrientsptopenergy?
,a. Metabolicpabsorption
b. Communication
c. Secretion
d. Respiration
ANS:p D
Thepcell’spabilityptopabsorbpoxygenpispreferredptopasprespirationpwhilepitspcommuni
cationpabilityinvolvespmaintenancepofpapsteadypdynamicpstate,pmetabolicpabsorptio
npprovidespnutrition,pandpsecretionpallowspforpthepsynthesizingpofpnewpsubstances.
REF:p p.p2
,3. ApeukaryoticpcellpispundergoingpDNApreplication.pInpwhichpregionpofpthepcellpwouldp
mostpofthepgeneticpinformationpbepcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleuspCytoplasm
ANS:p C
Thepregionpofpthepcellpthatpcontainspgeneticpmaterial,pincludingpaplargepamountpofprib
onucleicacid,pmostpofpthepDNA,pandpDNA-
bindingpproteins,pispthepnucleolus,pwhichpisplocatedpwithinthepcell’spnucleus.pMitocho
ndriapispassociatedpwithpcellularprespiration,pwhilepribosomesparepinvolvedpwithpprot
einpmanufacturing.pCytoplasmpispapfluidpfillingpthatpispapcomponentpofpthep cell.
REF:p p.p2
, 4. Whichpofpthepfollowingpcanpremovepproteinspattachedptopthepcell’spbilayerpbyp
dissolvingpthelayerpitself?
a. Peripheralpmembranepproteins
b. Integralpmembranepproteins
c. Glycoproteins
d. Cellpadhesionpmolecules
ANS:p B
Proteinspdirectlypattachedptopthepmembranepbilayerpcanpbepremovedpbypthepactionpofp
integralmembranepproteinspthatpdissolvepthepbilayer.pPeripheralpmembranepproteinsp
residepatpthepsurfacepwhilepcellpadhesionpmoleculespareponpthepoutsidepofpthepmembr
ane.pGlycoproteinpmarkspcellspandpdoespnotp float.
REF:p p.p7
5. Whichpofpthepfollowingpcanpbindptopplasmapmembranepreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicplipids
d. Ligands
ANS:p D
Ligandspareptheponlypspecificpmoleculespthatpcanpbindpwithpreceptorsponpthepcellpmembran
e.
REF:p p.p9
6. Apnursepispreviewingpapreportpfrompappatientpwithpmetastaticpcancer.pWhatpalter
nationpinptheextracellularpmatrixpwouldpsupportpthepdiagnosispofpmetastaticpcanc
er?
a. Decreasedpfibronectin
b. Increasedpcollagen
c. Decreasedpelastin
d. Increasedpglycoproteins
ANS:p A
Onlypapreducedpamountpofpfibronectinpispfoundpinpsomeptypespofpcancerouspcells,pallowingt
hemptoptravelporpmetastasize.
6th EDITION HUETHER
p
p p
CHAPTER 1-42 TEST BANK p p p
Chapterp01:pCellularpBiology
Huetherp&pMcCance:pUnderstandingpPathophysiology,p6thpEdition
MULTIPLEpCHOICE
1. Apstudentpispobservingpapcellpunderpthepmicroscope.pItpispobservedptophavepsuperco
iledpDNAwithphistones.pWhichpofpthepfollowingpwouldpalsopbepobservedpbypthepstu
dent?
a. Apsinglepcircularpchromosome
b. Apnucleus
c. Free-floatingpnuclearpmaterial
d. Noporganelles
ANS:p B
Thepcellpdescribedpispapeukaryoticpcell,psopitphasphistonespandpapsupercoiledpDNAp
withinpitsnucleus;pthus,pthepnucleuspshouldpbepobserved.pApsinglepcircularpchrom
osomepcalledpapprokaryotepcontainspfree-
floatingpnuclearpmaterialpbutphaspnoporganelles.
REF:p p.p2
2. Apnursepispinstructingpthepstaffpaboutpcellularpfunctions.pWhichpcellularpfunctionpisp
thepnursepdescribingpwhenpanpisolatedpcellpabsorbspoxygenpandpusespitptoptransformp
nutrientsptopenergy?
,a. Metabolicpabsorption
b. Communication
c. Secretion
d. Respiration
ANS:p D
Thepcell’spabilityptopabsorbpoxygenpispreferredptopasprespirationpwhilepitspcommuni
cationpabilityinvolvespmaintenancepofpapsteadypdynamicpstate,pmetabolicpabsorptio
npprovidespnutrition,pandpsecretionpallowspforpthepsynthesizingpofpnewpsubstances.
REF:p p.p2
,3. ApeukaryoticpcellpispundergoingpDNApreplication.pInpwhichpregionpofpthepcellpwouldp
mostpofthepgeneticpinformationpbepcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleuspCytoplasm
ANS:p C
Thepregionpofpthepcellpthatpcontainspgeneticpmaterial,pincludingpaplargepamountpofprib
onucleicacid,pmostpofpthepDNA,pandpDNA-
bindingpproteins,pispthepnucleolus,pwhichpisplocatedpwithinthepcell’spnucleus.pMitocho
ndriapispassociatedpwithpcellularprespiration,pwhilepribosomesparepinvolvedpwithpprot
einpmanufacturing.pCytoplasmpispapfluidpfillingpthatpispapcomponentpofpthep cell.
REF:p p.p2
, 4. Whichpofpthepfollowingpcanpremovepproteinspattachedptopthepcell’spbilayerpbyp
dissolvingpthelayerpitself?
a. Peripheralpmembranepproteins
b. Integralpmembranepproteins
c. Glycoproteins
d. Cellpadhesionpmolecules
ANS:p B
Proteinspdirectlypattachedptopthepmembranepbilayerpcanpbepremovedpbypthepactionpofp
integralmembranepproteinspthatpdissolvepthepbilayer.pPeripheralpmembranepproteinsp
residepatpthepsurfacepwhilepcellpadhesionpmoleculespareponpthepoutsidepofpthepmembr
ane.pGlycoproteinpmarkspcellspandpdoespnotp float.
REF:p p.p7
5. Whichpofpthepfollowingpcanpbindptopplasmapmembranepreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicplipids
d. Ligands
ANS:p D
Ligandspareptheponlypspecificpmoleculespthatpcanpbindpwithpreceptorsponpthepcellpmembran
e.
REF:p p.p9
6. Apnursepispreviewingpapreportpfrompappatientpwithpmetastaticpcancer.pWhatpalter
nationpinptheextracellularpmatrixpwouldpsupportpthepdiagnosispofpmetastaticpcanc
er?
a. Decreasedpfibronectin
b. Increasedpcollagen
c. Decreasedpelastin
d. Increasedpglycoproteins
ANS:p A
Onlypapreducedpamountpofpfibronectinpispfoundpinpsomeptypespofpcancerouspcells,pallowingt
hemptoptravelporpmetastasize.
