NBMEl 27l Testl V2l (Latestl 2025/l 2026l
Update)l Questionsl &l Answers|l Gradel A|l
100%l Correctl (Verifiedl Solution)
Q:l 35-year-oldl withl HIVl hasl firstl generalizedl tonicl seizure,l MRIl showsl al small,l
solitaryl enhancingl lesionl inl thel rightl frontall lobe,l biopsyl wouldl showl intensel
infiltrationl ofl lymphocytes,l plasmal cells,l macrophages,l andl numerousl 3X7l mml crescentl
shapedl organismsl withl al centrall nuclei,l thel lesionl regressl isl slowlyl afterl treatmentl withl
TMP-l SMX,l whichl ofl thel followingl isl mostl likelyl motivel transmissionl ofl thel infection?
Answer:
Ingestion-l catl fecesl orl infectedl meatl
Toxoplasmosisl Gondii
Q:l Nine-year-oldl hasl hairl lossl onl thel scalp.l Shel recentlyl startedl atl al newl privatel
schooll forl giftedl childrenl threel monthsl ago.l Scalpl showsl twol irregularlyl shaped,l quarterl
sizedl areasl ofl alopecial onl thel rightl sidel ofl thel head,l short,l brokenl hairsl arel notedl
withinl thesel areas,l nol scalingl orl erythema
Answer:
Trichotillomania
Q:l 20l year-oldl withl sicklel celll hasl chronicl hemolyticl anemial hasl frequentl painfull
crisisl thatl requirel transfusions,l hydroxyl treatmentl significantlyl decreasesl hisl painfull
crisisl andl transfusionl requirements,l whichl ofl thel followingl isl mostl likelyl mechanisml ofl
beneficiall effectsl ofl thisl treatment
Answer:
Increasedl hemoglobinl Fl concentration
Q:l Five-year-oldl withl introl uterinel growthl restrictionl isl continuingl tol growl slowly.l
Psychomotorl developmentl isl normal.l Geneticl thatl hasl uniparentall maternall heterodisomyl
,forl chromosomel seven.l Whichl ofl thel followingl mechanismsl bestl explainsl hisl slowl
growth?
Answer:
Genomicl imprintingl ofl growthl genes
Q:l Femalel newbornl isl foundl tol havel al clubl palettel withl cleftl lipl bilaterally,l nol
abnormalities,l failurel fusionl whichl ofl thel followingl prominencesl thel primaryl causesl ofl
thisl patient'sl cleftl lip?
Answer:
Maxillaryl andl nasall prominences
Q:l 48-year-oldl manl withl threel dayl historyl ofl fever,l chills,l headache,l nonproductive,l
off,l underwentl renall transplantationl fivel yearsl ago,l currentl medication'sl includel
corticosteroids,l coursel bronchi,l orl overl thel rightl lowerl lobe.l CXRl showsl al rightl lowerl
pneumonial withl smalll plurall effusion,l patientl isl treatedl withl anl antibioticl thatl inhibitsl
DNAl Gyrasel (Topioisomerase)l whatl isl it?
Answer:
Flouroquinolonesl |l Ciprofloxacin
Q:l 55-year-oldl womanl withl al historyl ofl alcoholl dependencel hasl severel epigastricl painl
andl isl vomitingl largel amountsl ofl blood,l hasl slightlyl ill.l Skinl andl conjunctiva,l abdomenl
isl largel andl distended,l bleedingl vesselsl arel mostl likelyl enlargedl duel tol increasel bloodl
flowl directlyl suppliedl byl whichl ofl thel followingl veins?
Answer:
Leftl Gastric
Q:l 60-year-oldl manl undergol tol Transrectall biopsyl ofl thel prostatel inl hospital,l fourl
hoursl laterl he'sl unablel tol urinate,l requiringl al placementl ofl al fullyl catheter.l Whichl ofl
thel followingl portionsl ofl thel eurol genitall tractl isl atl greatestl riskl forl rupturel duringl
placementl ofl thisl catheterl inl thisl patient?
Answer:
Membranousl urethral **Foleyl catheterl commonl injury**
,Q:l 25-year-oldl comesl tol thel officel whol isl pregnantl feelsl healthy.l Shel hasl noticedl
thatl herl RRl hasl increasedl froml 16l tol 22,l andl herl bloodl pressurel isl 100/60,l
examinationl showsl al normall fetusl size.l Whyl doesl shel havel increasedl respirations?
Answer:
Respiratoryl compensationl forl fetall metabolicl productionl ofl CO2
Q:l 13-year-oldl girll hasl fivel monthl historyl ofl behaviorall problems,l alternatesl froml
beingl sadl andl sociallyl withdrawnl Beingl extremelyl angryl andl aggressive,l diagnosisl ofl
bipolarl disorderl isl made,l treatmentl withl valproicl acid,l whichl inhibitsl histonel acetylasel
isl started.l Thel drugl isl mostl likelyl tol affect,l whichl ofl thel followingl processesl inl thisl
patient?
Answer:
Transcription
Q:l Patientl withl weightl loss,l feelingsl ofl uneasy,l onl edge,l palpitations,l increasedl vitals.l
Examl showsl exophthalmos.l Thyroidl isl enlarged,l smooth,l nontender,l seruml studyl showl
TSHl 0.1,l T4l ofl 20xl whatl isl thel dxl ?
Answer:
TSHl antibodies
Q:l 13-year-oldl girll hasl severall blemishesl onl facel andl backl forl eightl months,l
examinationl showl scatteredl comedonesl andl papulesl onl facel andl back.l Treatmentl withl
thel medicationl thatl decreasesl cohesionl betweenl epidermall cellsl andl increasesl epidermall
celll turnoverl isl initiated,l whichl drugl isl this?
Answer:
Tretinonin
Q:l 69-year-oldl manl withl hepaticl diseasel andl increasedl PTl isl scheduledl forl hipl
replacement,l thel manl receivesl al transfusionl ofl 1000l MLl ofl freshl frozenl plasma,l twol
hoursl laterl isl heat,l develops,l chills,l abdominall cramps,l SOB,l vomiting,l diarrhea,l whatl isl
thel causel ofl thisl reaction?l Whatl deficiency?
, Answer:
IgAl *theyl alsol havel recurrentl inflections*
Q:l 58l manl w/l HTNl (onl dieuriticzsl andl ACE),l osteoarthritis,l goutl (onl NSAIDs)l nowl
hasl fever,l fatigue,l andl malaise.l Allopurinoll wasl addedl tol regimenl 2l weeksl ago.l Hel hasl
al fever.l Erythematousl rashl overl thel interiorl trunk.l Labsl show:
Kl 5.6
Cal 8.5
BUNl 55
Creatininel 2.4
Phosl 4.9
Utical acidl 8.4l
Urine
pHl 7.5
Proteinl 1+
WBCl 5-7
RBCl 15-20
biopsyl showsl normall glomerulil andl al prominentl lymphocytic/Histeocyticl infiltratel thel
periglomerularl andl peritubularl tissues.l Occasionall eosinophill orl PMNS.l Nol necrosis.
Answer:
Immunel reaction
AIN-l AKIl w/l fever,l pyuria,l eosinophilia,l rash
NSAIDs
Diureticsl
Sulfonamidesl
Biopsyl showingl prominentl lymphocytic/histiocyticl infiltratel isl pathological
Q:l 27l year-oldl whol worksl inl al boilerl rooml isl notl ablel tol conceivel al childl forl thel
pastl threel years.l Hel hadl MUMPSl atl thel agel ofl 12.l Hisl wifel isl normal.l Muscularl andl
Update)l Questionsl &l Answers|l Gradel A|l
100%l Correctl (Verifiedl Solution)
Q:l 35-year-oldl withl HIVl hasl firstl generalizedl tonicl seizure,l MRIl showsl al small,l
solitaryl enhancingl lesionl inl thel rightl frontall lobe,l biopsyl wouldl showl intensel
infiltrationl ofl lymphocytes,l plasmal cells,l macrophages,l andl numerousl 3X7l mml crescentl
shapedl organismsl withl al centrall nuclei,l thel lesionl regressl isl slowlyl afterl treatmentl withl
TMP-l SMX,l whichl ofl thel followingl isl mostl likelyl motivel transmissionl ofl thel infection?
Answer:
Ingestion-l catl fecesl orl infectedl meatl
Toxoplasmosisl Gondii
Q:l Nine-year-oldl hasl hairl lossl onl thel scalp.l Shel recentlyl startedl atl al newl privatel
schooll forl giftedl childrenl threel monthsl ago.l Scalpl showsl twol irregularlyl shaped,l quarterl
sizedl areasl ofl alopecial onl thel rightl sidel ofl thel head,l short,l brokenl hairsl arel notedl
withinl thesel areas,l nol scalingl orl erythema
Answer:
Trichotillomania
Q:l 20l year-oldl withl sicklel celll hasl chronicl hemolyticl anemial hasl frequentl painfull
crisisl thatl requirel transfusions,l hydroxyl treatmentl significantlyl decreasesl hisl painfull
crisisl andl transfusionl requirements,l whichl ofl thel followingl isl mostl likelyl mechanisml ofl
beneficiall effectsl ofl thisl treatment
Answer:
Increasedl hemoglobinl Fl concentration
Q:l Five-year-oldl withl introl uterinel growthl restrictionl isl continuingl tol growl slowly.l
Psychomotorl developmentl isl normal.l Geneticl thatl hasl uniparentall maternall heterodisomyl
,forl chromosomel seven.l Whichl ofl thel followingl mechanismsl bestl explainsl hisl slowl
growth?
Answer:
Genomicl imprintingl ofl growthl genes
Q:l Femalel newbornl isl foundl tol havel al clubl palettel withl cleftl lipl bilaterally,l nol
abnormalities,l failurel fusionl whichl ofl thel followingl prominencesl thel primaryl causesl ofl
thisl patient'sl cleftl lip?
Answer:
Maxillaryl andl nasall prominences
Q:l 48-year-oldl manl withl threel dayl historyl ofl fever,l chills,l headache,l nonproductive,l
off,l underwentl renall transplantationl fivel yearsl ago,l currentl medication'sl includel
corticosteroids,l coursel bronchi,l orl overl thel rightl lowerl lobe.l CXRl showsl al rightl lowerl
pneumonial withl smalll plurall effusion,l patientl isl treatedl withl anl antibioticl thatl inhibitsl
DNAl Gyrasel (Topioisomerase)l whatl isl it?
Answer:
Flouroquinolonesl |l Ciprofloxacin
Q:l 55-year-oldl womanl withl al historyl ofl alcoholl dependencel hasl severel epigastricl painl
andl isl vomitingl largel amountsl ofl blood,l hasl slightlyl ill.l Skinl andl conjunctiva,l abdomenl
isl largel andl distended,l bleedingl vesselsl arel mostl likelyl enlargedl duel tol increasel bloodl
flowl directlyl suppliedl byl whichl ofl thel followingl veins?
Answer:
Leftl Gastric
Q:l 60-year-oldl manl undergol tol Transrectall biopsyl ofl thel prostatel inl hospital,l fourl
hoursl laterl he'sl unablel tol urinate,l requiringl al placementl ofl al fullyl catheter.l Whichl ofl
thel followingl portionsl ofl thel eurol genitall tractl isl atl greatestl riskl forl rupturel duringl
placementl ofl thisl catheterl inl thisl patient?
Answer:
Membranousl urethral **Foleyl catheterl commonl injury**
,Q:l 25-year-oldl comesl tol thel officel whol isl pregnantl feelsl healthy.l Shel hasl noticedl
thatl herl RRl hasl increasedl froml 16l tol 22,l andl herl bloodl pressurel isl 100/60,l
examinationl showsl al normall fetusl size.l Whyl doesl shel havel increasedl respirations?
Answer:
Respiratoryl compensationl forl fetall metabolicl productionl ofl CO2
Q:l 13-year-oldl girll hasl fivel monthl historyl ofl behaviorall problems,l alternatesl froml
beingl sadl andl sociallyl withdrawnl Beingl extremelyl angryl andl aggressive,l diagnosisl ofl
bipolarl disorderl isl made,l treatmentl withl valproicl acid,l whichl inhibitsl histonel acetylasel
isl started.l Thel drugl isl mostl likelyl tol affect,l whichl ofl thel followingl processesl inl thisl
patient?
Answer:
Transcription
Q:l Patientl withl weightl loss,l feelingsl ofl uneasy,l onl edge,l palpitations,l increasedl vitals.l
Examl showsl exophthalmos.l Thyroidl isl enlarged,l smooth,l nontender,l seruml studyl showl
TSHl 0.1,l T4l ofl 20xl whatl isl thel dxl ?
Answer:
TSHl antibodies
Q:l 13-year-oldl girll hasl severall blemishesl onl facel andl backl forl eightl months,l
examinationl showl scatteredl comedonesl andl papulesl onl facel andl back.l Treatmentl withl
thel medicationl thatl decreasesl cohesionl betweenl epidermall cellsl andl increasesl epidermall
celll turnoverl isl initiated,l whichl drugl isl this?
Answer:
Tretinonin
Q:l 69-year-oldl manl withl hepaticl diseasel andl increasedl PTl isl scheduledl forl hipl
replacement,l thel manl receivesl al transfusionl ofl 1000l MLl ofl freshl frozenl plasma,l twol
hoursl laterl isl heat,l develops,l chills,l abdominall cramps,l SOB,l vomiting,l diarrhea,l whatl isl
thel causel ofl thisl reaction?l Whatl deficiency?
, Answer:
IgAl *theyl alsol havel recurrentl inflections*
Q:l 58l manl w/l HTNl (onl dieuriticzsl andl ACE),l osteoarthritis,l goutl (onl NSAIDs)l nowl
hasl fever,l fatigue,l andl malaise.l Allopurinoll wasl addedl tol regimenl 2l weeksl ago.l Hel hasl
al fever.l Erythematousl rashl overl thel interiorl trunk.l Labsl show:
Kl 5.6
Cal 8.5
BUNl 55
Creatininel 2.4
Phosl 4.9
Utical acidl 8.4l
Urine
pHl 7.5
Proteinl 1+
WBCl 5-7
RBCl 15-20
biopsyl showsl normall glomerulil andl al prominentl lymphocytic/Histeocyticl infiltratel thel
periglomerularl andl peritubularl tissues.l Occasionall eosinophill orl PMNS.l Nol necrosis.
Answer:
Immunel reaction
AIN-l AKIl w/l fever,l pyuria,l eosinophilia,l rash
NSAIDs
Diureticsl
Sulfonamidesl
Biopsyl showingl prominentl lymphocytic/histiocyticl infiltratel isl pathological
Q:l 27l year-oldl whol worksl inl al boilerl rooml isl notl ablel tol conceivel al childl forl thel
pastl threel years.l Hel hadl MUMPSl atl thel agel ofl 12.l Hisl wifel isl normal.l Muscularl andl
