Questions & Answers New Update
Rotigotine - Answers -✔✔ Neupro patch: do not heat/ use during MRI
HLA b1502 - Answers -✔✔ Test in Asians. Rash for carbamazepine (tegretol),
phenytoin (Dilantin), fos phenytoin (cerebyx)
Trastuzumab - Answers -✔✔ Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib
(tykerb) pertuzumab (perjeta)
Hla- b 5701 - Answers -✔✔ Don't give abacavir (ziagen), epzicom, trizivir
Not cross reactive a/ opioid allergy - Answers -✔✔ Fentanyl, meperidine (Demerol),
methadone (dolophine), tramadol (ultram), tapentadol (nucynta)
Inducers - Answers -✔✔ Ps porcs (phenytoin, smoking, phenobarbital, oxcarbazepine,
rifampin, carbamazepine, St. John's wort)
Inhibitors - Answers -✔✔ Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine,
macrolides- erytho/clarithro, amiodarone, non dihydro (dilt, verapamil)
If on amiodarone, decrease these drugs by 30-50% - Answers -✔✔ Digoxin, warfarin,
quinidine, procainanide, statins
Statins with high risk of inhibition - Answers -✔✔ Las (lova, atorva, simva)
Entecavir - Answers -✔✔ Baraclude. Empty stomach for hep B that fail lamivudime and
adefovir- se: peripheral edema, nephrotoxic
Ribavirin - Answers -✔✔ Copegus. W/ food bid for hep c, hepatotoxic, hemolytic
anemia, preg x, psych disorders, ci: renal disfxn
Glipizide - Answers -✔✔ Glucotrol 30 min before break & dinner
Glimeprimide - Answers -✔✔ Amaryl 1-2 mg qd w/ 1st meal
Glyburide - Answers -✔✔ Diabeta, + metformin = glucovance, do not use w/ renal
failure 2.5-5mg qd
Rosiglitazone - Answers -✔✔ Avandia 4-8mg qd (tzd, exacerbate hf, liver damage,
increases hdl, decreases tg/total cholesterol) similar: pioglitazone (actos)
, Repaglinide - Answers -✔✔ Prandin 0.5-2mg TID 15-30 min before a meal,
hypoglycemia- do not take with su's
Nateglinide - Answers -✔✔ Starlix injection- 15-30 min before meals
Acarbose - Answers -✔✔ Precose- w/ 1st bite of meal and water
Miglitol - Answers -✔✔ Glyset w/ 1st bite of meal and water
Linagliptan - Answers -✔✔ Tradjenta- 5 mg qd in morning with or without food, no renal
adjustment
Saxagliptin - Answers -✔✔ OnglyZa 2.5-5mg qd
Canaglifozin - Answers -✔✔ Invokana 100mg qd before first meal of day for DM. Se:
female genital mycotic infxn, increased urination, hyperkalemia, can increase dig levels,
ci: renal dx
Exenatide - Answers -✔✔ Byetta 30-60 min before am & pm meals,medguide,
pancreatitis, thyroid c-cell carcinoma xr= bydureon
Liraglutide - Answers -✔✔ Victoza QD thyroid c-cell carcinoma, more weight loss, less
pancreatitis
Pramlintide - Answers -✔✔ Symlin - injection, skip if no meals, weight loss
Insulin aspart - Answers -✔✔ Novolog rapid
Insulin glulisine - Answers -✔✔ Apidra rapid
Insulin lispro - Answers -✔✔ Humalog rapid
Detemir - Answers -✔✔ Levemir long acting
Insulin glargine - Answers -✔✔ Lantus long acting
Ibandronate - Answers -✔✔ Boniva 150 monthly
Zolendrenic acid - Answers -✔✔ Reclast iv - pretreat w/nsaids
Teriparatide - Answers -✔✔ Forteo SC daily: osteosarcoma, kidney stones, orthostatic
hypotension, hypocalcemia- must take ca starting 2 weeks before time- fridge after each
dose, sit while giving