Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton

Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton
Complete

,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
x. x. x. x. x. x. x. x.




Clayton’sBasicPharmacology forNurses,19thEdition
x. x. x. x. x. x. x.




MULTIPLECHOICE x.




1. Whichname identifies a druglisted bythe US Food and
x. x. x. x. x. x. x. x. x. x.




x. Drug Administration (FDA)?x. x.




a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C x.




The official name is the name under which a drug is listed by
x. x. x. x. x . x. x. x. x. x. x. x.




the FDA. The brand name, or trademark, is the name given to
x. x. x. x. x. x. x. x. x. x. x. x.




a drug by its manufacturer. The nonproprietary, or generic,
x. x. x. x. x. x. x. x. x.




name is provided by the United States Adopted Names
x. x. x. x. x. x. x. x. x.




Council.
x.




DIF: Cognitive Level: Knowledge REF: p. 9 x. x. x . x.




OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care x. x. x. x. x. x. x. x.




Environment TOP: Nursing Process Step: Assessment
x. CON: x. x . x. x. x.




Patient Education
x. x.




2. Whichsource contains information specific to nutritional supplements?
x. x. x. x. x. x. x.




a. USPDictionary of USAN &International Drug Names x. x. x. x. .x x. x.




b. NaturalMedicines Comprehensive Database x. x. x.




c. UnitedStatesPharmacopoeia/National Formulary (USPNF) x. x. x. x. x.




d. DrugInteraction Facts .x x.




ANS: C x.




UnitedStatesPharmacopoeia/National Formularycontains information specificto nutritional
x. x. x. x. x. x. x. x.




supplements. USP Dictionary of USAN &International Drug Names is a compilation of drug
x. x. x. x. x. x. x. x. x. x. x. x. x. x.




names, pronunciation guide, and possible future FDA approved drugs; it does not include
x. x. x. x. x. x. x. x. x. x. x. x. x.




nutritional supplements. Natural Medicines Comprehensive Database contains
x. x. x. x. x. x. x.




evidence-based information onherbal medicines and herbal combination products; it doesnot x. x. x. x. x. x. x. x. x. x. x.




include information specific to nutritional supplements. Drug Interaction Facts contains
x. x. x. x. x. x. x. x. x. x.




comprehensive information on drug interaction facts; it does not include nutritional
x. x. x. x. x. x. x. x. x. x. x.




supplements.
x.




DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 x. x. x . x. x.




NAT: NCLEX Client Needs Category: Physiological Integrity
x. x . x. x. x. x. x.




TOP: NursingProcess Step: Assessment CON: Nutrition |Patient Education
x . x. x. x. x . x. x. x.




3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
x. x. x. x. x. x. x. x. x. x. x. x. x.




a. Drug Facts and Comparisons x. x. x.

,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
x. x. x. x. x. x. x. x. x. 3

b. DrugInteraction Facts .x x.




c. Handbook on Injectable Drugs x. x. x.




d. Martindale—TheCompleteDrug Reference x. x. x.




ANS: A x.




Drug Facts and Comparisons contains drug monographs that describe all drugs in a
x. x. x. x. x. x. x. x. x. x. x. x.




therapeutic class. Monographs are formatted as tablesto allow comparison ofsimilar
x. x. x. x. x. x. x. x. x. x. x. x.




products, brand names, manufacturers, cost indices, and available dosage forms Online
x. x. x. x. x. x. x. x. x. x. x.




version is available.
x. x. x.




DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 x. x. x . x. x. x.




OBJ: 3 x . NAT: NCLEXClient NeedsCategory:Physiological Integrity
x . x. x. x. x. x. x.




TOP: NursingProcess Step: Assessment CON: Safety|Patient Education |Clinical Judgment
x . x. x. x. x . x. x. x. x. x. x.




4. Whichdrugreference contains monographs about virtuallyeverysingle-entitydrug available in
x. x. x. x. x. x. x. x. x. x. x.




the United States and describes therapeutic uses of drugs, including approved and unapproved
x. x. x. x. x. x. x. x. x. x. x. x. x.




uses?
x.




a. Martindale: TheComplete DrugReference x. x. x. x.




b. AHFSDrug Information x. x.




c. DrugReference x.




d. DrugFacts and Comparisons x. x. x.




ANS: B x.




AHFS Drug Information contains monographs about virtually every single-entity drug
x. x. x. x. x. x. x. x. x.




available inthe United States and describes therapeutic uses ofdrugs, including approved and
x. x. x. x. x. x. x. x. x. x. x. x. x. x.




unapproved uses.
x. x.




DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 x. x. x . x. x. x.




OBJ: 3 x . NAT: NCLEXClientNeedsCategory:Physiological Integrity
x . x. x. x. x. x. x.




TOP: NursingProcess Step: Planning
x . CON: Safety|Patient Education |Clinical Judgment x. x. x. x . x. x. x. x. x. x.




5. Which online drug reference makes available to healthcare providers and the public a
x. x. x. x. x. x. x. x. x. x. x. x.




standard, comprehensive, up-to-datelook upand downloadable resource about medicines?
x. x. x. x. x. x. x. x. x. x.




a. AmericanDrug Index x. x.




b. AmericanHospital Formulary x. x.




c. DailyMed
d. DrugReference x.




ANS: C x.




DailyMed makes available to healthcare providers and the public astandard, comprehensive, up-
x. x. x. x. x. x. x. x. x. x. x. x.




to-datelook up and downloadable resource about medicines. The American Drug Indexis not
x. x. x. x. x. x. x. x. x. x. x. x. x.




appropriate for patient use. The American Hospital Formulary is not appropriate for patient
x. x. x. x. x. x. x. x. x. x. x. x. x.




use. The drug reference is not appropriate for patient use.
x. x. x. x. x. x. x. x. x. x.




DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 x. x. x . x. x. x. x. OBJ:3 x.




NAT: NCLEX Client Needs Category: Physiological Integrity
x. x . x. x. x. x. x.




TOP: NursingProcess Step: Implementation
x. x. x. x.




CON: Safety |Patient Education |Clinical Judgment
x . x. x
. x. x. x. x.




6. Which legislation authorizes the FDA to determine the safetyofadrug before its marketing?
x. x. x. x. x. x. x. x. x. x. x. x. x. x.




a. Federal Food, Drug, and Cosmetic Act (1938) x. x. x. x. x. x.




b. DurhamHumphreyAmendment (1952) x. x. x.

, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
x. x. x. x. x. x. x. x. x. 4

c. ControlledSubstances Act (1970) x. x. x.




d. KefauverHarrisDrugAmendment (1962) x. x. x. x.




ANS: A x.




The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety
x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




of all drugs before marketing. Later amendments and acts helped tighten FDA control and
x. x. x. x. x. x. x. x. x. x. x. x. x. x.




ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot
x. x. x. x. x. x. x. x. x. x. x. x. x. x.




be used safely without medical supervision and restricts their sale to prescription by a licensed
x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




practitioner. The Controlled Substances Act addresses onlycontrolled substances and their
x. x. x. x. x. x. x. x. x. x. x.




categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
x. x. x. x. x. x. x. x. x. x. x. x.




safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




before marketing them.
x. x. x.




DIF: Cognitive Level: Knowledge REF: p. 5Table l.3 x. x. x . x. x. x.




OBJ: x . 5 NAT: NCLEX Client Needs Category: Physiological Integrity x. x. x. x. x. x.




TOP:
x. x . Nursing Process Step: Assessment x. x. x.




CON: Safety |Patient Education |Evidence |Health Care Law
x . x. x
. x. x. x. x. x. x. x.




7. Whichclassificationdoes meperidine (Demerol) fallunder?
x. x. x. x. x. x.




a. I
b. II
c. III
d. IV
ANS: B x.




Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to x. x. x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




severepsychological and physical dependence. Schedule Idrugs have high potential forabuse and
x. x. x. x. x. x. x. x. x. x. x. x. x. x.




no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to
x. x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




low to moderate physical dependence or high psychological dependence. Schedule IV drugs
x. x. x. x. x. x. x. x. x. x. x. x.




have low potential for abuse. Use may lead to limited physical or psychological dependence.
x. x. x. x. x. x. x. x. x. x. x. x. x. x.




DIF: Cognitive Level: Knowledge REF: p. 10 OBJ:2 x. x. x . x. x.




NAT: NCLEX Client Needs Category: Safe, Effective CareEnvironment
x. x . x. x. x. x. x. x. x.




TOP: NursingProcess Step: Assessment CON: Patient Education |Addiction |Pain
x . x. x. x. x . x. x. x. x. x.




8. Which action would the FDAtake to expedite drugdevelopment and approval for an outbreak of
x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




x. smallpox?
a. List smallpox as a health orphandisease. x. x. x. x. x. x.




b. Omit thepreclinical research phase. x. x. x. x.




c. Extendthe clinicalresearch phase. x. x. x. x.




d. Fasttrackthe investigationaldrug. x. x. x. x.




ANS: D x.




Once the Investigational New Drug Application has been approved, the drug can receive
x. x. x. x. x. x. x. x. x. x. x. x.




highest priority within the agency, which is called fast tracking. A smallpox outbreak would
x. x. x. x. x. x. x. x. x. x. x. x. x. x.




become a priority concern in the world. Orphan diseases are not researched in a priority
x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




manner. Preclinical research is not omitted. Extending any phase of the research would mean a
x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




longer time to develop avaccine. The FDAmust ensurethat all phases of the preclinical and
x. x. x. x. x. x. x. x. x. x. x. x. x. x. x. x. x.




clinical research phase have been completed in a safe manner.
x. x. x. x. x. x. x. x. x. x.




DIF: Cognitive Level: Knowledge x. x. REF: x . x . p. 7 x. OBJ: 5 x.