(LIBRIUM)
GENERIC NAME: (CHLORDIAZEPOXIDE HYDROCHLORIDE)
Drug Class: Benzodiazepine anxiolytics
NAMES PURPOSE/THERAPEUTIC USES
Generic Name: • Management of anxiety disorders
• Short-term relief of symptoms of anxiety
Chlordiazepoxide HCl • Withdrawal symptoms of acute alcoholism
Brand Name(s): Librium • Preoperative apprehension and anxiety
DIAGNOSES TREATED
Side Effects/Adverse Reactions
◦ ANXIETY
Drowsiness Blood dyscrasias and agranulocytos
◦ ACUTE ALCOHOL Dizziness Jaundice
WITHDRAWAL Ataxia Hepatic and renal dysfunction
Confusion Blurred vision
Edema Skin rash
Menstrual irregularities Headache
DOSAGING Nausea and vomiting Paradoxical reactions
Constipation Depression
Capsule, gelatin coated
EPS Hallucinations
5mg, 10mg, 20mg, 25mg
Increased and decreased libido Sleep disturbances
IM/IV
* Used initially for relief of withdrawal
symptoms of acute alcoholism; 100mg
Nursing Considerations
Hold medication if BP falls 20mm Hg or more or if pulse rate above 120 bpm
Monitor liver function and blood counts periodically for prolonged treatment
ADDITIONAL INFO Monitor for orthostatic hypotension and tachycardia with parenteral administration
Withdrawal symptoms may occur after Contraindications
discontinuation and sudden discontinuation
may be life threatening Pregnancy and breast feeding
Gradual tapering scheduled should be Alcohol and opioid use
followed Hypersensitivity
May interact with barbiturates, blood Under 6 years of age
thinners, MAO inhibitors, psychiatric Primary depressive disorder or psychoses
medications, narcotics, or antidepressants
Impaired hepatic or renal function
GENERIC NAME: (CHLORDIAZEPOXIDE HYDROCHLORIDE)
Drug Class: Benzodiazepine anxiolytics
NAMES PURPOSE/THERAPEUTIC USES
Generic Name: • Management of anxiety disorders
• Short-term relief of symptoms of anxiety
Chlordiazepoxide HCl • Withdrawal symptoms of acute alcoholism
Brand Name(s): Librium • Preoperative apprehension and anxiety
DIAGNOSES TREATED
Side Effects/Adverse Reactions
◦ ANXIETY
Drowsiness Blood dyscrasias and agranulocytos
◦ ACUTE ALCOHOL Dizziness Jaundice
WITHDRAWAL Ataxia Hepatic and renal dysfunction
Confusion Blurred vision
Edema Skin rash
Menstrual irregularities Headache
DOSAGING Nausea and vomiting Paradoxical reactions
Constipation Depression
Capsule, gelatin coated
EPS Hallucinations
5mg, 10mg, 20mg, 25mg
Increased and decreased libido Sleep disturbances
IM/IV
* Used initially for relief of withdrawal
symptoms of acute alcoholism; 100mg
Nursing Considerations
Hold medication if BP falls 20mm Hg or more or if pulse rate above 120 bpm
Monitor liver function and blood counts periodically for prolonged treatment
ADDITIONAL INFO Monitor for orthostatic hypotension and tachycardia with parenteral administration
Withdrawal symptoms may occur after Contraindications
discontinuation and sudden discontinuation
may be life threatening Pregnancy and breast feeding
Gradual tapering scheduled should be Alcohol and opioid use
followed Hypersensitivity
May interact with barbiturates, blood Under 6 years of age
thinners, MAO inhibitors, psychiatric Primary depressive disorder or psychoses
medications, narcotics, or antidepressants
Impaired hepatic or renal function
