SEROQUEL
GENERIC NAME: QUETIAPINE
Drug Class: Antipsychotics, 2nd Generation, Antimanic Agents
NAMES PURPOSE/THERAPEUTIC USES
Generic Name: Quetiapine • Rebalances dopamine and serotonin to improve thinking,
mood, and behavior
Brand Name(s): Seroquel, • Can help treat the following: hallucinations, delusions,
Seroquel XR disorganized thinking, acute mania, depression
• Treats adults and children 13 & up
DIAGNOSES TREATED
Side Effects/Adverse Reactions
◦ SCHIZOPHRENIA
Neuroleptic malignant syndrome Tachycardia
◦ BIPOLAR DISORDER (fever, altered mental status, Akathisia (restlessness)
muscle rigidity, autonomic
◦ MAJOR DEPRESSIVE dysfunction, HTN, hypotension) Dystonia
Seizures
DISORDER (WITH Pseudoparkinsonism (mask-like face
rigidity, tremors, drooling, Syncope
ANTIDEPRESSENT) shuffling gait, dysphasia)
Increased thirst; dry mouth
◦ ADHD Orthostatic Hypotension
Mouth or skin sores
Involuntary rhythmic movement of
Trouble breathing
mouth, face, and extremities
Severe constipation
Weight gain
DOSAGING Diaphoresis
Stevens-Johnson syndrome (rash)
Tablet (immediate release)
25mg, 50mg, 100mg, 200mg, 300mg, 400mg Nursing Considerations
BEERS drug--Use with caution in elderly patients
Tablet (extended release) QT interval prolongation
25mg, 50mg, 100mg, 200mg, 300mg, 400mg Do not use with CNS depressants (ex. benzodiazepines)
Assess weight frequently
Max Daily Dose Monitor liver function test (LFT) and CBC
800mg of IR May increase cholesterol
Caution with patients who have a history of cardiac arrythmia, hypokalemia,
hypomagnesemia
ADDITIONAL INFO Contraindications
Not recommended for individuals who are No known FDA contraindications
pregnant or breastfeeding
GENERIC NAME: QUETIAPINE
Drug Class: Antipsychotics, 2nd Generation, Antimanic Agents
NAMES PURPOSE/THERAPEUTIC USES
Generic Name: Quetiapine • Rebalances dopamine and serotonin to improve thinking,
mood, and behavior
Brand Name(s): Seroquel, • Can help treat the following: hallucinations, delusions,
Seroquel XR disorganized thinking, acute mania, depression
• Treats adults and children 13 & up
DIAGNOSES TREATED
Side Effects/Adverse Reactions
◦ SCHIZOPHRENIA
Neuroleptic malignant syndrome Tachycardia
◦ BIPOLAR DISORDER (fever, altered mental status, Akathisia (restlessness)
muscle rigidity, autonomic
◦ MAJOR DEPRESSIVE dysfunction, HTN, hypotension) Dystonia
Seizures
DISORDER (WITH Pseudoparkinsonism (mask-like face
rigidity, tremors, drooling, Syncope
ANTIDEPRESSENT) shuffling gait, dysphasia)
Increased thirst; dry mouth
◦ ADHD Orthostatic Hypotension
Mouth or skin sores
Involuntary rhythmic movement of
Trouble breathing
mouth, face, and extremities
Severe constipation
Weight gain
DOSAGING Diaphoresis
Stevens-Johnson syndrome (rash)
Tablet (immediate release)
25mg, 50mg, 100mg, 200mg, 300mg, 400mg Nursing Considerations
BEERS drug--Use with caution in elderly patients
Tablet (extended release) QT interval prolongation
25mg, 50mg, 100mg, 200mg, 300mg, 400mg Do not use with CNS depressants (ex. benzodiazepines)
Assess weight frequently
Max Daily Dose Monitor liver function test (LFT) and CBC
800mg of IR May increase cholesterol
Caution with patients who have a history of cardiac arrythmia, hypokalemia,
hypomagnesemia
ADDITIONAL INFO Contraindications
Not recommended for individuals who are No known FDA contraindications
pregnant or breastfeeding
