NUR 211 EXAM 3 QUESTIONS AND
CORRECT ANSWERS
Sickle cell how to diagnosis ANSW✅✅CBC - low hematocrit
Hgb electrophoresis
What is sickle cell acute Vaso-occlusive crisis? ANSW✅✅Very painful, rbc and WBC entrapment
causing tissue hypoxia, inflammation, and necrosis due to inadequate blood flow
What is sickle cell aplastic crisis? ANSW✅✅Due to parvovirus, rapid fall in HgB were bone marrow
cannot compensate
What is sickle cell sequestration crisis? ANSW✅✅Other organs (specifically spleen) affected by
pooling of sickle cells
What triggers a sickle cell crisis? ANSW✅✅Illness
Stress
Alcohol
Dehydration
Cold weather
High altitude
Complications of sickle cell anemia ANSW✅✅Anemia, Pulmonary hypertension, Acute chest
syndrome, heart/renal failure, CVA/Stroke, infection, leg ulcers, eye damage, substance abuse
How do you treat sickle cell anemia? ANSW✅✅Management of symptoms, therapies (rx,
procedural, supportive)
Sickle cell anemia predisposition ANSW✅✅African american
Central africa
The near east
Mesiterranean
, Aboriginals
Hispanics (caribbean, central and south america)
Sickle cell anemia clinical manifestations ANSW✅✅Fatigue
Weakness
Pain
Swelling
Tachycardia
Murmur
Enlargement of bones in face and skull
What are procedural therapies to treat sickle cell anemia? ANSW✅✅Hematopoietic stem cell
transplantation, transcranial doppler studies
What RX therapy is used to treat sickle cell anemia? ANSW✅✅Hydroxyurea
Nsaids
Morphine
Opioids
Antibiotics (pcn)
Corticosteroids
What class of drugs is hydroxyurea to treat sickle cell anemia ANSW✅✅Antineoplastic
What is the typical dose for sickle cell patients using hydroxyurea? ANSW✅✅15-35mg/kg/day
How does hydroxyurea work for sickle cell anemia? ANSW✅✅Increases fetal hgb in children,
decreased number of circulating lymphocytes, decreases pain with crisis
What are the adverse reactions associated with hydroxyurea used for sickle cell disease?
ANSW✅✅Thrombocytopenia
Leukopenia
CORRECT ANSWERS
Sickle cell how to diagnosis ANSW✅✅CBC - low hematocrit
Hgb electrophoresis
What is sickle cell acute Vaso-occlusive crisis? ANSW✅✅Very painful, rbc and WBC entrapment
causing tissue hypoxia, inflammation, and necrosis due to inadequate blood flow
What is sickle cell aplastic crisis? ANSW✅✅Due to parvovirus, rapid fall in HgB were bone marrow
cannot compensate
What is sickle cell sequestration crisis? ANSW✅✅Other organs (specifically spleen) affected by
pooling of sickle cells
What triggers a sickle cell crisis? ANSW✅✅Illness
Stress
Alcohol
Dehydration
Cold weather
High altitude
Complications of sickle cell anemia ANSW✅✅Anemia, Pulmonary hypertension, Acute chest
syndrome, heart/renal failure, CVA/Stroke, infection, leg ulcers, eye damage, substance abuse
How do you treat sickle cell anemia? ANSW✅✅Management of symptoms, therapies (rx,
procedural, supportive)
Sickle cell anemia predisposition ANSW✅✅African american
Central africa
The near east
Mesiterranean
, Aboriginals
Hispanics (caribbean, central and south america)
Sickle cell anemia clinical manifestations ANSW✅✅Fatigue
Weakness
Pain
Swelling
Tachycardia
Murmur
Enlargement of bones in face and skull
What are procedural therapies to treat sickle cell anemia? ANSW✅✅Hematopoietic stem cell
transplantation, transcranial doppler studies
What RX therapy is used to treat sickle cell anemia? ANSW✅✅Hydroxyurea
Nsaids
Morphine
Opioids
Antibiotics (pcn)
Corticosteroids
What class of drugs is hydroxyurea to treat sickle cell anemia ANSW✅✅Antineoplastic
What is the typical dose for sickle cell patients using hydroxyurea? ANSW✅✅15-35mg/kg/day
How does hydroxyurea work for sickle cell anemia? ANSW✅✅Increases fetal hgb in children,
decreased number of circulating lymphocytes, decreases pain with crisis
What are the adverse reactions associated with hydroxyurea used for sickle cell disease?
ANSW✅✅Thrombocytopenia
Leukopenia
