Nagelhout Pharmacology Exam 1|
96 Complete Questions and
Answers
Pharmacology - -the study of the effect of chemicals on living tissue
- Pharmacokinetics - -the study of the absorption, distribution, metabolism
and excretion of drugs
- Pharmaceutics - -the formulation and preparation of drugs.
- Pharmacoeconomics - -the study of the economic impact of drugs
- Toxicology - -the study of the harmful effects of chemicals.
- Pharmacognosy - -the study of the medicinal uses of naturally occurring
compounds
- Pharmacy - -the preparation and dispensing of drugs
- Pharmacogenetics - -genetic influences by and on drugs
- Pharmacodynamics - -physiological and biochemical mechanism of action
of drugs
- Pharmacogenomics - -identifies discrete genetic differences among
individuals that play a critical role in drug response
- Pharmacoepidemiology - -the study of the use and effects of drugs on
large groups of people.
- receptor theory - -pharmacodynamics
- Pharmacokinetics - -Drug absorption, distribution, metabolism, excretion
- 1. Receptor theory: pharmacodynamics
2. Pharmacokinetics: Drug absorption, distribution, metabolism, excretion
3. Autonomic nervous system terminology
4. Anesthetic goals - -What are the four introductory areas of anesthesia
pharmacology?
- LIGANDS for that receptor - -Chemical substances that bind to a specific
receptor are referred to as:
, - 1. agonists
2, antagonists - -What are the two types of ligands?
- agonists - -what binds to a receptor and stimulate the function that
receptor serves
- antagonists - -binds to a receptor and block the function that receptor
serves
- reversible - -Competitive binding =
- nonreversible - -Noncompetitive binding =
- ED50 - -EFFECTIVE DOSE IN 50% OF THE POPULATION
- TD50 - -TOXIC DOSE IN 50% OF THE POPULATION
- LD50 - -LETHAL DOSE IN 50% OF THE POPULATION
- LD50/ED50 - -THERAPEUTIC INDEX
- Therapeutic window (or pharmaceutical window) TD50/ED50 - -an index
for estimation of drug dosage which can treat disease effectively while
staying within the safety range.
OR EXPRESSED AS .....
- covalent
ionic
hydrogen
hydrophobic
van der waals - -types of bonds from strongest to weakest:
- (1) Affinity (potency)
(2) Efficacy
(3) Variability
(4) Slope - -Dose Response Curves allow you to determine:
- Therapeutic window - -a range of doses or plasma concentrations that
produces therapeutic response without causing any significant adverse effect
in patients.
- desensitization, also referred to as refractoriness or down-regulation - -
Continued stimulation of cells with agonists generally results in a state of
_____, such that the effect that follows continued or subsequent exposure to
the same concentration of drug is diminished
96 Complete Questions and
Answers
Pharmacology - -the study of the effect of chemicals on living tissue
- Pharmacokinetics - -the study of the absorption, distribution, metabolism
and excretion of drugs
- Pharmaceutics - -the formulation and preparation of drugs.
- Pharmacoeconomics - -the study of the economic impact of drugs
- Toxicology - -the study of the harmful effects of chemicals.
- Pharmacognosy - -the study of the medicinal uses of naturally occurring
compounds
- Pharmacy - -the preparation and dispensing of drugs
- Pharmacogenetics - -genetic influences by and on drugs
- Pharmacodynamics - -physiological and biochemical mechanism of action
of drugs
- Pharmacogenomics - -identifies discrete genetic differences among
individuals that play a critical role in drug response
- Pharmacoepidemiology - -the study of the use and effects of drugs on
large groups of people.
- receptor theory - -pharmacodynamics
- Pharmacokinetics - -Drug absorption, distribution, metabolism, excretion
- 1. Receptor theory: pharmacodynamics
2. Pharmacokinetics: Drug absorption, distribution, metabolism, excretion
3. Autonomic nervous system terminology
4. Anesthetic goals - -What are the four introductory areas of anesthesia
pharmacology?
- LIGANDS for that receptor - -Chemical substances that bind to a specific
receptor are referred to as:
, - 1. agonists
2, antagonists - -What are the two types of ligands?
- agonists - -what binds to a receptor and stimulate the function that
receptor serves
- antagonists - -binds to a receptor and block the function that receptor
serves
- reversible - -Competitive binding =
- nonreversible - -Noncompetitive binding =
- ED50 - -EFFECTIVE DOSE IN 50% OF THE POPULATION
- TD50 - -TOXIC DOSE IN 50% OF THE POPULATION
- LD50 - -LETHAL DOSE IN 50% OF THE POPULATION
- LD50/ED50 - -THERAPEUTIC INDEX
- Therapeutic window (or pharmaceutical window) TD50/ED50 - -an index
for estimation of drug dosage which can treat disease effectively while
staying within the safety range.
OR EXPRESSED AS .....
- covalent
ionic
hydrogen
hydrophobic
van der waals - -types of bonds from strongest to weakest:
- (1) Affinity (potency)
(2) Efficacy
(3) Variability
(4) Slope - -Dose Response Curves allow you to determine:
- Therapeutic window - -a range of doses or plasma concentrations that
produces therapeutic response without causing any significant adverse effect
in patients.
- desensitization, also referred to as refractoriness or down-regulation - -
Continued stimulation of cells with agonists generally results in a state of
_____, such that the effect that follows continued or subsequent exposure to
the same concentration of drug is diminished
