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ABSITE Exam Questions And Answers 2025 Update.

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©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM. 1 ABSITE Exam Questions And Answers 2025 Update. Which nutrient is poorly absorbed in achlorhydria? a.) Vitamin D b.) Vitamin B12 c.) Bile salts d.) Proteins e.) Fats - Answer(b) Vitamin B12 Hypophosphatemia has been associated with all of the following EXCEPT: a.) impaired diaphragmatic contractility b.) treated diabetic ketoacidosis c.) malabsorption coupled with carbohydrate refeeding d.) chronic alcoholism e.) respiratory muscle hyperresponsiveness - Answer(e) It is seen in patients with chronic alcoholism, diabetic ketoacidosis, sepsis, and severe malnutrition after carbohydrate refeeding. It can also be seen in surgical patients who are not receiving enough phosphate repletion from parenteral nutrition. Hypophosphatemia causes ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM. 2 muscle weakness, and probably affects the diaphragm more than other muscles, therefore leading to respiratory failure. Studies have shown lower contractility of the diaphragm Phosphorus deficiency may lead to insulin resistance as well What is the main nutrient for colonocytes? a.) Glutamine b.) Alanine c.) Short chain fatty acids d.) Glucose - Answer(c) Short chain fatty acids (Note: the primary fuel source though for enterocytes is glutamine) What chemotherapy agent leads to pulmonary fibrosis? a.) Doxorubicin b.) Methotrexate c.) Bleomycin d.) Vincristine e.) Cyclophosphamide - Answer(c) What is the most useful serum marker for cancer screening? a.) PSA b.) CEA c.) AFP d.) CA 19-9 e.) CA 15-3 - Answer(a) ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM. 3 All others are used for follow-up or diagnosis What is the embryologic origin of the inferior parathyroid gland? a.) 4th arch b.) 4th pouch c.) 3rd arch d.) 3rd pouch - Answer(d) Derivatives of the 3rd pouch include the inferior parathyroid glands and the thymus. The main nerve supply is the glossopharyngeal nerve. Superior parathyroids come from the 4th pouch What is the cause of hypotension and decreased EtCO2 during laparoscopic surgery a.) Tension pneumothorax b.) Inferior vena cava compression c.) CO2 embolus d.) Anesthetic overdose - Answer(c) Increased levels of glutamine are associated with all of the following EXCEPT: a.) decreased incidence of clinical infections in patients receiving bone marrow transplantation b.) vitro suppression of hepatoma growth c.) alleviation of depletion of muscle glutamine stores d.) decreased glutathione levels in tumor cells during radiation therapy or chemotherapy e.) increased tumor growth in patients with advanced malignant disease - Answer(e) ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM. 4 Glutamine, the most abundant amino acid in the body, can be trapped by a growing tumor, depleting the body's glutamine stores and producing cachexia. A prospective, randomized, double-blind trial demonstrated that patients undergoing bone marrow transplantation had significantly decreased clinical infections when they received supplemental glutamine. Glutamine also reduced the glutathione levels in tumor cells of patients undergoing chemotherapy or radiation therapy. The concern that administering glutamine would promote tumor growth has proven unfounded. Which of the following is an inhibitor of wound contraction? a.) Aspirin b.) d-penicillamine c.) Colchicine d.) Glucocorticoids - Answer(c) In contrast to adults, fetal wound healing biochemistry is characterized by which of the following? a.) ↑ inflmmatory phase b.) ↑ content of type III collagen c.) ↑ level of transforming growth factor-B d.) ↓ hyaluronic acid synthesis - Answer(a) Death from postoperative renal failure is most commonly due to? a.) Myocardial infarction b.) Bleeding c.) Sepsis d.) Liver failure - Answer(c) ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM. 5 In hyperacute rejection of a recently transplanted kidney, the event associated with organ loss is: a.) Direct antibody effect on interstitial stromal cells. b.) Ischemia. c.) Antigen antibody complexes

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©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM.




ABSITE Exam Questions And Answers 2025
Update.


Which nutrient is poorly absorbed in achlorhydria?


a.) Vitamin D
b.) Vitamin B12
c.) Bile salts
d.) Proteins

e.) Fats - Answer✔(b)


Vitamin B12


Hypophosphatemia has been associated with all of the following EXCEPT:


a.) impaired diaphragmatic contractility
b.) treated diabetic ketoacidosis
c.) malabsorption coupled with carbohydrate refeeding
d.) chronic alcoholism

e.) respiratory muscle hyperresponsiveness - Answer✔(e)


It is seen in patients with chronic alcoholism, diabetic ketoacidosis, sepsis, and severe
malnutrition after carbohydrate refeeding. It can also be seen in surgical patients who are not
receiving enough phosphate repletion from parenteral nutrition. Hypophosphatemia causes



1

, ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM.


muscle weakness, and probably affects the diaphragm more than other muscles, therefore
leading to respiratory failure. Studies have shown lower contractility of the diaphragm
Phosphorus deficiency may lead to insulin resistance as well


What is the main nutrient for colonocytes?


a.) Glutamine
b.) Alanine
c.) Short chain fatty acids

d.) Glucose - Answer✔(c)


Short chain fatty acids
(Note: the primary fuel source though for enterocytes is glutamine)


What chemotherapy agent leads to pulmonary fibrosis?


a.) Doxorubicin
b.) Methotrexate
c.) Bleomycin
d.) Vincristine

e.) Cyclophosphamide - Answer✔(c)


What is the most useful serum marker for cancer screening?


a.) PSA
b.) CEA
c.) AFP
d.) CA 19-9

e.) CA 15-3 - Answer✔(a)

2

, ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM.




All others are used for follow-up or diagnosis


What is the embryologic origin of the inferior parathyroid gland?


a.) 4th arch
b.) 4th pouch
c.) 3rd arch

d.) 3rd pouch - Answer✔(d)


Derivatives of the 3rd pouch include the inferior parathyroid glands and the thymus. The main
nerve supply is the glossopharyngeal nerve. Superior parathyroids come from the 4th pouch


What is the cause of hypotension and decreased EtCO2 during laparoscopic surgery


a.) Tension pneumothorax
b.) Inferior vena cava compression
c.) CO2 embolus

d.) Anesthetic overdose - Answer✔(c)


Increased levels of glutamine are associated with all of the following EXCEPT:


a.) decreased incidence of clinical infections in patients receiving bone marrow transplantation
b.) vitro suppression of hepatoma growth
c.) alleviation of depletion of muscle glutamine stores
d.) decreased glutathione levels in tumor cells during radiation therapy or chemotherapy

e.) increased tumor growth in patients with advanced malignant disease - Answer✔(e)




3

, ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11AM.


Glutamine, the most abundant amino acid in the body, can be trapped by a growing tumor,
depleting the body's glutamine stores and producing cachexia. A prospective, randomized,
double-blind trial demonstrated that patients undergoing bone marrow transplantation had
significantly decreased clinical infections when they received supplemental glutamine.
Glutamine also reduced the glutathione levels in tumor cells of patients undergoing
chemotherapy or radiation therapy. The concern that administering glutamine would promote
tumor growth has proven unfounded.


Which of the following is an inhibitor of wound contraction?


a.) Aspirin
b.) d-penicillamine
c.) Colchicine

d.) Glucocorticoids - Answer✔(c)


In contrast to adults, fetal wound healing biochemistry is characterized by which of the
following?


a.) ↑ inflmmatory phase
b.) ↑ content of type III collagen
c.) ↑ level of transforming growth factor-B

d.) ↓ hyaluronic acid synthesis - Answer✔(a)


Death from postoperative renal failure is most commonly due to?


a.) Myocardial infarction
b.) Bleeding
c.) Sepsis

d.) Liver failure - Answer✔(c)




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