rau-s respiratory care pharmacology 9th edition gardenhire test bank.

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RAU’s Respiratory Care Pharmacology
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9TH EDITIONr




BY GARDENHIRE
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TESTBANK r

,Description
Test Bank for Rau’s Respiratory Care Pharmacology 9th Edition Gardenhire
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Test Bank for Rau’s Respiratory Care Pharmacology, 9th Edition, Gardenhire, ISBN-
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10: 0323299687, ISBN-13: 9780323299688
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Table of Contents
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Unit I: Basic Concepts and Principles in Pharmacology
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1. Introduction to Respiratory Care Pharmacology
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2. Principles of Drug Action
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3. Administration of Aerosolized Agents
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4. Calculating Drug Doses
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5. The Central and Peripheral Nervous Systems
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Unit II: Drugs Used to Treat the Respiratory System
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6. Adrenergic (Sympathomimetic) Bronchodilators
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7. Anticholinergic (Parasympatholytic) Bronchodilators
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8. Xanthines
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9. Mucus-Controlling Drug Therapy
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10. Surfactant Agents
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11. Corticosteriods in Respiratory Care
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12. Nonsteroidal Antiasthma Agents
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13. Aerosolized Antiinfective Agents
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14. Antimicrobial Agents
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15. Cold and Cough Agents
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16. Selected Agents of Pulmonary Value
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17. Neonatal and Pediatric Aerosolized Drug Therapy
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Unit III: Critical Care, Cardiovascular, and Polysomnography Agents
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18. Skeletal Muscle Relaxants (Neuromuscular Blocking Agents)
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19. Diuretic Agents
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20. Drugs Affecting the Central Nervous System
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21. Vasopressors, Inotropes, and Antiarrythmic Agents
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22. Drugs Affecting Circulation: Antihypertensives, Antianginals, Antithrombotics
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23. Sleep and Sleep Pharmacology
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,Chapter 01: Introduction to Respiratory Care Pharmacology Gardenhire:
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Rau’s Respiratory Care Pharmacology, 9th Edition
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MULTIPLE CHOICE r




1. What is the name of the receptor sites that are located in the peripheral vasculature, the heart, bronchial musc
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le, and bronchial blood vessels?
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a. Beta 2 receptors r r c. Alpha receptors r


b. Gamma receptors d. Beta 1 receptors
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ANS: C r


Alpha receptors are located in the peripheral vasculature, the heart, bronchial muscle, and bronchial blood
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vessels.

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2. Which receptor site results in tachycardia, an increased potential for arrhythmias, and an increased card
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iac output? r


a. Beta 1 receptor r r c. Alpha receptor r


b. Beta 2 receptor r r d. Delta receptor r r




ANS: A r


Stimulation of the beta- r r r



1 receptors results in tachycardia, an increased potential for arrhythmias, and an increased cardiac output. I
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n administering drugs to the pulmonary system, stimulation of the beta-
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1 sites is not desired. However, most respiratory pharmacologic agents have some beta-
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1 stimulatory effect.
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3. Stimulation of the beta 2 receptors causes r r r r r r r


a. peripheral vasoconstriction and mild bronchoconstriction in the lungs.
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b. tachycardia, an increased potential for arrhythmias, and an increased cardiac output.
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c. bronchodilation.
d. peripheral vasodilation, bradycardia, and decreased cardiac output.
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ANS: C r


Stimulation of the beta-2 receptors in the lungs causes bronchodilation.
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4. Acetylcholine stimulates r r


a. the Vagus nerve. r r


b. the adrenergic receptors. r r


c. the sympathetic nervous system.
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d. the cholinergic receptors.r r




ANS: D r


Acetylcholine stimulates the cholinergic receptors. r r r r




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5. What immunoglobulin antibody sensitizes the mast cell?
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a. Leukotrienes c. Histamine

, b. IgE d. Prostaglandins
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ANS: B r


The IgE (reagin) antibodies sensitize the mast cell. Repeated exposure to the antigen causes the degranulati
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on of the mast cell.
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6. Which of the following is caused by histamine release from the mast cells?
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I. Bronchodilation
II. Increased bronchial gland secretion r r r


III. Increased amount of mucus present in the airways r r r r r r r


a. I and II only r c. III only
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b. II and III only r d. I, II, III
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ANS: B r


Histamine is also a potent bronchoconstrictor. In addition to its bronchoconstrictive activity, histamine
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II) increases bronchial gland secretion, causing III) an increase in the amount of mucus present in
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the airways. Histamine may also have an effect on vascular permeability similar to the effect of- SRS-A.
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7. A sympathomimetic drug would cause
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a. bronchodilation. c. Histamine release. r


b. bronchoconstriction. d. Vagus nerve stimulation.
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ANS: A r


A sympathomimetic drug would cause bronchodilation. Sympathomimetic agents are the drugs most commonly us
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ed to reverse bronchospasm.
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8. Stimulation of the sympathetic nervous system causes r r r r r r r


a. vascular permeability. c. bronchodilation. r


b. decreased blood pressure. d. bronchoconstriction. r r r




ANS: C r


Sympathetic nervous system stimulation causes bronchodilation. r r r r r




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9. Which of the following would NOT cause a bronchospasm or bronchoconstriction?
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a. Leukotrienes c. Histamine
b. Beta 1 receptors d. Prostaglandins
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ANS: B r


Beta-
1 receptors would not cause a bronchospasm or bronchoconstriction. Leukotrienes are one of many ch
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emical mediators released by the mast cells. Leukotrienes cause a direct, strong bronchoconstriction. Hista
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mine is also a potent bronchoconstrictor. Prostaglandins cause a strong bronchospasm, especially in asthm
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atic patients. r




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