Exam Questions and CORRECT Answers
Management of BMI >/= 25 - CORRECT ANSWER - Diet, Exercise, Behavior
Management of BMI >/=30 - CORRECT ANSWER - Diet, exercise, behavior +
pharmacotherapy
Management of BMI >/= 27 + comorbidity - CORRECT ANSWER - Diet, exercise,
behavior + pharmacotherapy
Management of BMI >/=35 + cormorbidity - CORRECT ANSWER - Bariatric surgery
Management of BMI >/=40 - CORRECT ANSWER - Bariatric surgery
Co-morbidities - CORRECT ANSWER - T2DM
HTN
OSA and other respiratory disorders
NAFLD
OA
lipid abnormalities
gastrointestinal disorders
heart disease
Medication assessment - CORRECT ANSWER - Every month x3 months, then every 3
months
Effective weight loss % - CORRECT ANSWER - >/=5% in 3 months
,Avoid these wt loss meds with HTN/HD - CORRECT ANSWER - Sympathomimetics
(phentermine/diethylproprion)
Avoid these wt loss medications with CVD - CORRECT ANSWER - Sypathomimetics
T2DM treatment + medications to support weight loss - CORRECT ANSWER - GLP-1
analog (mitigates associated weight gain due to insulin) or SGLT-2 inhibitors + metformin. If
using insulin, recommend basal instead of combo
Drugs that induce weight gain - CORRECT ANSWER - Tricyclic antidepressants
(Amitriptyline)
oral contraceptives (Ortho Tri-Cyclen, Yaz)
antipsychotics (Risperidone)
anticonvulsants
glucocorticoids (cortisol)
sulfonyureas- ( Glimepiride, Glipizide)
glitazones (Actos)
B-blockers (Propranolol, Metoprolol, Atenolol)
Hormonal signals for appetite - CORRECT ANSWER - CCK- duodenum
K cells- duodenum and jejunum: gatric inhibitory polypeptide
PYY- ileum and colon
GLP-1 -ileum
Pancreas- Insulin
Adipose tissue: Leptin
, Liver- glucagon
GLP-1 - CORRECT ANSWER - Secreted in response to glucose and promotes insulin
release from pancreas and satiety
Ghrelin - CORRECT ANSWER - produced in the stomach, orexigenic
Leptin - CORRECT ANSWER - proportional to fat mass, anorexigenic
Inhibits appetite
PYY - CORRECT ANSWER - Ileum and colon, anorexigenic
CCK - CORRECT ANSWER - duodenum, anorexigenic
Insulin - CORRECT ANSWER - Pancreas, anorexigenic
Phentermine - CORRECT ANSWER - noradrenergic, dopaminergic sympathomimetic
amine
Start with 7.5-15mg/d, increase only with no results
Do not prescribe for someone with hx of psych dz or substance abuse
Lorcaserin (Belviq) - CORRECT ANSWER - Seratonin agent, stimulates seratonin type 2
receptor
Brand name: Phentermine/Topiramate - CORRECT ANSWER - Qysemia